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1Y6D
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SOLUTION STRUCTURE AND DYNAMICS OF LUXU FROM VIBRIO HARVEYI, A PHOSPHOTRANSFERASE PROTEIN INVOLVED IN BACTERIAL QUORUM SENSING
Descriptor:Phosphorelay protein luxU
Authors:Ulrich, D.L., Kojetin, D., Bassler, B.L., Cavanagh, J., Loria, J.P.
Deposit date:2004-12-06
Release date:2004-12-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing.
J.Mol.Biol., 347, 2005
1U1B
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STRUCTURE OF BOVINE PANCREATIC RIBONUCLEASE A IN COMPLEX WITH 3'-PHOSPHOTHYMIDINE (3'-5')-PYROPHOSPHATE ADENOSINE 3'-PHOSPHATE
Descriptor:Ribonuclease, pancreatic, 5'-PHOSPHOTHYMIDINE (3'-5')-PYROPHOSPHATE ADENOSINE 3'-PHOSPHATE
Authors:Beach, H., Cole, R., Gill, M.L., Loria, J.P.
Deposit date:2004-07-15
Release date:2005-06-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conservation of mus-ms enzyme motions in the apo- and substrate-mimicked state.
J.Am.Chem.Soc., 127, 2005
2AKG
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THALLIUM FORM OF THE G-QUADRUPLEX FROM OXYTRICHA NOVA, D(G4T4G4)2
Descriptor:5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3'
Authors:Gill, M.L., Strobel, S.A., Loria, J.P.
Deposit date:2005-08-03
Release date:2005-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:(205)Tl NMR methods for the characterization of monovalent cation binding to nucleic acids
J.Am.Chem.Soc., 127, 2005
2HBN
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CRYSTALLIZATION OF THE TL+-FORM OF THE OXYTRICHA NOVA G-QUADRUPLEX
Descriptor:5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', THALLIUM (I) ION
Authors:Gill, M.L., Strobel, S.A., Loria, J.P.
Deposit date:2006-06-14
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystallization and characterization of the thallium form of the Oxytricha nova G-quadruplex.
Nucleic Acids Res., 34, 2006
2PCV
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SOLUTION STRUCTURE OF AN RRNA SUBSTRATE BOUND TO THE PSEUDOURIDYLATION POCKET OF A BOX H/ACA SNORNA
Descriptor:U65 Box H/ACA snoRNA
Authors:Jin, H., Loria, J.P., Moore, P.B.
Deposit date:2007-03-30
Release date:2007-05-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an rRNA substrate bound to the pseudouridylation pocket of a box H/ACA snoRNA.
Mol.Cell, 26, 2007
2PCW
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SOLUTION STRUCTURE OF AN RRNA SUBSTRATE BOUND TO THE PSEUDOURIDYLATION POCKET OF A BOX H/ACA SNORNA
Descriptor:U65 box H/ACA snoRNA, rRNA substrate of U65 box H/ACA snoRNA
Authors:Jin, H., Loria, J.P., Moore, P.B.
Deposit date:2007-03-30
Release date:2007-05-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of an rRNA substrate bound to the pseudouridylation pocket of a box H/ACA snoRNA.
Mol.Cell, 26, 2007
3LXO
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THE CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH THYMIDINE-3'-MONOPHOSPHATE
Descriptor:Ribonuclease pancreatic, THYMIDINE-3'-PHOSPHATE
Authors:Doucet, N., Jayasundera, T.B., Simonovic, M., Loria, J.P.
Deposit date:2010-02-25
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding.
Proteins, 78, 2010
6OLQ
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P188A MUTANT, APO STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, ACETATE ION, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-04-16
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6OLV
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P185A MUTANT, APO STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL, ACETATE ION
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-04-17
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6OMY
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P180A MUTANT, APO STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-04-19
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6PFW
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), T177A MUTANT, APO STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL, ACETATE ION
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-06-22
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6PG0
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P188A MUTANT, VANADATE BOUND STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-06-23
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6PGT
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), T177A MUTANT, VANADATE BOUND STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-06-24
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6PHA
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), F182A MUTANT, VANADATE BOUND STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION, GLYCEROL, ...
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-06-25
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6PHS
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P185A MUTANT, VANADATE BOUND STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-06-25
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.129 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
6PM8
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P180A MUTANT, VANADATE BOUND STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-07-01
Release date:2019-08-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B.
J.Am.Chem.Soc., 141, 2019
4P61
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CHICKEN TRIOSEPHOSPHATE ISOMERASE WITH LOOP6 MUTATIONS, V167P AND W168E.
Descriptor:Triosephosphate isomerase
Authors:Pegan, S.D., Mesecar, A.D.
Deposit date:2014-03-21
Release date:2014-08-27
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase.
Biochemistry, 53, 2014
4GUM
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CYSTAL STRUCTURE OF LOCKED-TRIMER OF HUMAN MIF
Descriptor:Macrophage migration inhibitory factor, CHLORIDE ION
Authors:Fan, C., Lolis, E.
Deposit date:2012-08-29
Release date:2013-07-03
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations.
Proc.Natl.Acad.Sci.USA, 110, 2013
5EIZ
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CRYSTAL STRUCTURE OF Y99A MUTANT OF HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, GLYCEROL, SULFATE ION, ...
Authors:Pantouris, G., Lolis, E.
Deposit date:2015-10-30
Release date:2015-11-11
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 2018
5UZY
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CRYSTAL STRUCTURE OF N97A MUTANT OF HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ...
Authors:Pantouris, G., Lolis, E.
Deposit date:2017-02-27
Release date:2018-02-28
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 57, 2018
6BG6
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CRYSTAL STRUCTURE OF S111A MUTANT OF HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ...
Authors:Pantouris, G., Lolis, E.
Deposit date:2017-10-27
Release date:2018-06-06
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 57, 2018
6BG7
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CRYSTAL STRUCTURE OF G107A MUTANT OF HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ...
Authors:Pantouris, G., Lolis, E.
Deposit date:2017-10-27
Release date:2018-06-06
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 57, 2018
6BTE
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DNA POLYMERASE BETA I260Q BINARY COMPLEX
Descriptor:DNA polymerase beta, DNA Template Strand, DNA Primer Strand, ...
Authors:Eckenroth, B.E., Doublie, S.
Deposit date:2017-12-06
Release date:2018-09-26
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity.
Nucleic Acids Res., 46, 2018
6BTF
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DNA POLYMERASE BETA I260Q TERNARY COMPLEX
Descriptor:DNA polymerase beta, DNA Template Strand, DNA Primer Strand, ...
Authors:Eckenroth, B.E., Doublie, S.
Deposit date:2017-12-06
Release date:2018-09-26
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity.
Nucleic Acids Res., 46, 2018
6DR1
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YOPH PTP1B CHIMERA 2 PTPASE
Descriptor:Targeted effector protein
Authors:Morales, Y., Johnson, S.J., Hengge, A.C.
Deposit date:2018-06-11
Release date:2018-08-29
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018
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