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5ME0
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BU of 5me0 by Molmil
Structure of the 30S Pre-Initiation Complex 1 (30S IC-1) Stalled by GE81112
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S.
Deposit date:2016-11-14
Release date:2017-01-11
Last modified:2019-11-13
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
5ME1
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BU of 5me1 by Molmil
Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S.
Deposit date:2016-11-14
Release date:2017-01-11
Last modified:2019-11-13
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
5NO3
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BU of 5no3 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate without uS3)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO4
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BU of 5no4 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO2
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BU of 5no2 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-24
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
7ZZ4
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BU of 7zz4 by Molmil
Cryo-EM structure of "BC closed" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ8
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BU of 7zz8 by Molmil
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA and cyclic di-AMP
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ0
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BU of 7zz0 by Molmil
Cryo-EM structure of "CT empty" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Pyruvate carboxylase
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ2
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BU of 7zz2 by Molmil
Cryo-EM structure of "CT pyr" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZYZ
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BU of 7zyz by Molmil
Cryo-EM structure of "CT oxa" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MANGANESE (II) ION, OXALOACETATE ION, Pyruvate carboxylase
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ3
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BU of 7zz3 by Molmil
Cryo-EM structure of "BC react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ1
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BU of 7zz1 by Molmil
Cryo-EM structure of "CT react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: BIOTIN, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ5
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BU of 7zz5 by Molmil
Cryo-EM structure of "BC open" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, BICARBONATE ION, Pyruvate carboxylase
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZYY
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BU of 7zyy by Molmil
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-10-12
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.12 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ6
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BU of 7zz6 by Molmil
Cryo-EM structure of "CT-CT dimer" of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ...
Authors:Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
Deposit date:2022-05-25
Release date:2022-12-28
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.15 Å)
Cite:CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7JSR
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BU of 7jsr by Molmil
Crystal structure of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis
Descriptor: NAD-specific glutamate dehydrogenase
Authors:Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N.
Deposit date:2020-08-15
Release date:2021-06-09
Last modified:2021-07-14
Method:X-RAY DIFFRACTION (6.27 Å)
Cite:3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme.
Commun Biol, 4, 2021
7A1D
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BU of 7a1d by Molmil
Cryo-EM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis (open conformation)
Descriptor: NAD-specific glutamate dehydrogenase
Authors:Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N.
Deposit date:2020-08-12
Release date:2021-06-09
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (4.19 Å)
Cite:3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme.
Commun Biol, 4, 2021
4YHH
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BU of 4yhh by Molmil
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Dhimole, N, Zhou, S, Lopez-Alonso, J.P, Connell, S.R, Fucini, P.
Deposit date:2015-02-27
Release date:2015-04-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.417 Å)
Cite:Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
7NAX
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BU of 7nax by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAS
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BU of 7nas by Molmil
Bacterial 30S ribosomal subunit assembly complex state A (multibody refinement for body domain of 30S ribosome)
Descriptor: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-07-07
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAR
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BU of 7nar by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state F (+RsgA)(Consensus Refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAU
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BU of 7nau by Molmil
Bacterial 30S ribosomal subunit assembly complex state C (Consensus Refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAT
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BU of 7nat by Molmil
Bacterial 30S ribosomal subunit assembly complex state A (Consensus refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAV
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BU of 7nav by Molmil
Bacterial 30S ribosomal subunit assembly complex state D (Consensus refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7AF3
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BU of 7af3 by Molmil
Bacterial 30S ribosomal subunit assembly complex state M (head domain)
Descriptor: 16S rRNA (head), 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R.
Deposit date:2020-09-19
Release date:2021-07-07
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021

 

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