3P5T | | CFIM25-CFIM68 COMPLEX | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6 | | Authors: | Li, H., Tong, S., Li, X., Shi, H., Gao, Y., Ge, H., Niu, L., Teng, M. | | Deposit date: | 2010-10-11 | | Release date: | 2010-11-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
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3P6Y | | CF IM25-CF IM68-UGUAA COMPLEX | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 5, Cleavage and polyadenylation specificity factor subunit 6, 5'-R(*UP*GP*UP*AP*A)-3' | | Authors: | Li, H., Tong, S., Li, X., Shi, H., Gao, Y., Ge, H., Niu, L., Teng, M. | | Deposit date: | 2010-10-11 | | Release date: | 2010-11-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
To be Published
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3MD1 | | CRYSTAL STRUCTURE OF THE SECOND RRM DOMAIN OF YEAST POLY(U)-BINDING PROTEIN (PUB1) | | Descriptor: | Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1, GLYCEROL | | Authors: | Li, H., Shi, H., Li, Y., Cui, Y., Niu, L., Teng, M. | | Deposit date: | 2010-03-29 | | Release date: | 2010-05-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)
To be published
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5XF7 | |
2AXH | | CRYSTAL STRUCTURES OF T CELL RECEPTOR BETA CHAINS RELATED TO RHEUMATOID ARTHRITIS | | Descriptor: | T cell receptor beta chain | | Authors: | Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y. | | Deposit date: | 2005-09-05 | | Release date: | 2005-09-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
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2AXJ | | CRYSTAL STRUCTURES OF T CELL RECEPTOR BETA CHAINS RELATED TO RHEUMATOID ARTHRITIS | | Descriptor: | SF4 T cell receptor beta chain | | Authors: | Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y. | | Deposit date: | 2005-09-05 | | Release date: | 2005-09-20 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
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1ADB | | CRYSTALLOGRAPHIC STUDIES OF ISOSTERIC NAD ANALOGUES BOUND TO ALCOHOL DEHYDROGENASE: SPECIFICITY AND SUBSTRATE BINDING IN TWO TERNARY COMPLEXES | | Descriptor: | ALCOHOL DEHYDROGENASE, ZINC ION, 5-BETA-D-RIBOFURANOSYLNICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | Authors: | Li, H., Hallows, W.A., Punzi, J.S., Pankiewicz, K.W., Watanabe, K.A., Goldstein, B.M. | | Deposit date: | 1993-12-13 | | Release date: | 1995-06-03 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystallographic studies of isosteric NAD analogues bound to alcohol dehydrogenase: specificity and substrate binding in two ternary complexes.
Biochemistry, 33, 1994
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1ADC | | CRYSTALLOGRAPHIC STUDIES OF ISOSTERIC NAD ANALOGUES BOUND TO ALCOHOL DEHYDROGENASE: SPECIFICITY AND SUBSTRATE BINDING IN TWO TERNARY COMPLEXES | | Descriptor: | ALCOHOL DEHYDROGENASE, ZINC ION, 5-BETA-D-RIBOFURANOSYLPICOLINAMIDE ADENINE-DINUCLEOTIDE, ... | | Authors: | Li, H., Hallows, W.A., Punzi, J.S., Pankiewicz, K.W., Watanabe, K.A., Goldstein, B.M. | | Deposit date: | 1993-12-13 | | Release date: | 1995-06-03 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystallographic studies of isosteric NAD analogues bound to alcohol dehydrogenase: specificity and substrate binding in two ternary complexes.
Biochemistry, 33, 1994
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1LZX | | RAT NEURONAL NOS HEME DOMAIN WITH NG-HYDROXY-L-ARGININE BOUND | | Descriptor: | Nitric-oxide synthase, ACETATE ION, ZINC ION, ... | | Authors: | Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L. | | Deposit date: | 2002-06-11 | | Release date: | 2002-11-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide
Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
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1LZZ | | RAT NEURONAL NOS HEME DOMAIN WITH N-ISOPROPYL-N'-HYDROXYGUANIDINE BOUND | | Descriptor: | Nitric-oxide synthase, ACETATE ION, ZINC ION, ... | | Authors: | Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L. | | Deposit date: | 2002-06-11 | | Release date: | 2002-11-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide
Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
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1M00 | | RAT NEURONAL NOS HEME DOMAIN WITH N-BUTYL-N'-HYDROXYGUANIDINE BOUND | | Descriptor: | Nitric-oxide synthase, ACETATE ION, ZINC ION, ... | | Authors: | Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L. | | Deposit date: | 2002-06-11 | | Release date: | 2002-11-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide
Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
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1OM4 | | STRUCTURE OF RAT NEURONAL NOS HEME DOMAIN WITH L-ARGININE BOUND | | Descriptor: | Nitric-oxide synthase, brain, ZINC ION, ... | | Authors: | Li, H., Martasek, P., Shimizu, H., Masters, B.S.S., Poulos, T.L., Raman, C.S. | | Deposit date: | 2003-02-24 | | Release date: | 2003-03-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure of Rat Neuronal NOS Heme Domain with L-Arginine Bound
To be Published
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1ZZQ | | RAT NNOS D597N MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND | | Descriptor: | Nitric-oxide synthase, brain, ACETATE ION, ... | | Authors: | Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L. | | Deposit date: | 2005-06-14 | | Release date: | 2005-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
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1ZZR | | RAT NNOS D597N/M336V DOUBLE MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND | | Descriptor: | Nitric-oxide synthase, brain, ZINC ION, ... | | Authors: | Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L. | | Deposit date: | 2005-06-14 | | Release date: | 2005-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
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1ZZS | | BOVINE ENOS N368D SINGLE MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND | | Descriptor: | Nitric-oxide synthase, endothelial, ACETATE ION, ... | | Authors: | Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L. | | Deposit date: | 2005-06-14 | | Release date: | 2005-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
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1ZZT | | BOVINE ENOS N368D/V106M DOUBLE MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND | | Descriptor: | Nitric-oxide synthase, endothelial, ACETATE ION, ... | | Authors: | Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L. | | Deposit date: | 2005-06-14 | | Release date: | 2005-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
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1ZZU | | RAT NNOS D597N/M336V DOUBLE MUTANT WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND | | Descriptor: | Nitric-oxide synthase, brain, ACETATE ION, ... | | Authors: | Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L. | | Deposit date: | 2005-06-14 | | Release date: | 2005-12-06 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
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2OJE | | MYCOPLASMA ARTHRITIDIS-DERIVED MITOGEN COMPLEXED WITH CLASS II MHC MOLECULE HLA-DR1/HA COMPLEX IN THE PRESENCE OF EDTA | | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain precursor, DRB1-1 beta chain precursor, ... | | Authors: | Li, H., Zhao, Y., Guo, Y., Li, Z., Eisele, L., Mourad, W. | | Deposit date: | 2007-01-12 | | Release date: | 2007-01-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.
J.Biol.Chem., 282, 2007
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1ADF | | CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN | | Descriptor: | ALCOHOL DEHYDROGENASE, ZINC ION, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE | | Authors: | Li, H., Hallows, W.A., Punzi, J.S., Marquez, V.E., Carrell, H.L., Pankiewicz, K.W., Watanabe, K.A., Goldstein, B.M. | | Deposit date: | 1993-10-18 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
Biochemistry, 33, 1994
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1ADG | | CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN | | Descriptor: | ALCOHOL DEHYDROGENASE, ZINC ION, BETA-METHYLENE-SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE | | Authors: | Li, H., Hallows, W.A., Punzi, J.S., Marquez, V.E., Carrell, H.L., Pankiewicz, K.W., Watanabe, K.A., Goldstein, B.M. | | Deposit date: | 1993-10-18 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
Biochemistry, 33, 1994
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3MD3 | | CRYSTAL STRUCTURE OF THE FIRST TWO RRM DOMAINS OF YEAST POLY(U) BINDING PROTEIN (PUB1) | | Descriptor: | Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1, SULFATE ION, GLYCEROL | | Authors: | Li, H., Shi, H., Zhu, Z., Wang, H., Niu, L., Teng, M. | | Deposit date: | 2010-03-29 | | Release date: | 2010-05-05 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)
To be published
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1D1W | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 2-AMINOTHIAZOLINE (H4B BOUND) | | Descriptor: | NITRIC OXIDE SYNTHASE, ACETATE ION, ZINC ION, ... | | Authors: | Li, H., Raman, C.S., Martasek, P., Kral, V., Masters, B.S.S., Poulos, T.L. | | Deposit date: | 1999-09-21 | | Release date: | 2000-10-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
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1K2R | | STRUCTURE OF RAT BRAIN NNOS HEME DOMAIN COMPLEXED WITH NG-NITRO-L-ARGININE | | Descriptor: | nitric-oxide synthase, ACETATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L., Raman, C.S. | | Deposit date: | 2001-09-28 | | Release date: | 2003-03-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of rat brain nNOS heme domain
To be Published
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1K2S | | STRUCTURE OF RAT BRAIN NNOS HEME DOMAIN COMPLEXED WITH NG-ALLYL-L-ARGININE | | Descriptor: | nitric-oxide synthase, ACETATE ION, ZINC ION, ... | | Authors: | Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L., Raman, C.S. | | Deposit date: | 2001-09-28 | | Release date: | 2003-03-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure of rat brain nNOS heme domain
To be Published
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1K2T | | STRUCTURE OF RAT BRAIN NNOS HEME DOMAIN COMPLEXED WITH S-ETHYL-N-PHENYL-ISOTHIOUREA | | Descriptor: | nitric-oxide synthase, ACETATE ION, ZINC ION, ... | | Authors: | Li, H., Martasek, P., Masters, B.S.S., Poulos, T.L., Raman, C.S. | | Deposit date: | 2001-09-28 | | Release date: | 2003-03-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of rat brain nNOS heme domain
To be Published
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