Author results

6EY0
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N-TERMINAL PART (RESIDUES 30-212) OF PORM WITH THE LLAMA NANOBODY NB01
Descriptor:T9SS component cytoplasmic membrane protein PorM, llama nanobody nb01
Authors:Leone, P., Roche, J., Cambillau, C., Roussel, A.
Deposit date:2017-11-10
Release date:2018-02-07
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.
Nat Commun, 9, 2018
6EY5
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C-TERMINAL PART (RESIDUES 224-515) OF PORM
Descriptor:T9SS component cytoplasmic membrane protein PorM, ZINC ION
Authors:Leone, P., Cambillau, C., Roussel, A.
Deposit date:2017-11-10
Release date:2018-02-07
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.
Nat Commun, 9, 2018
6EY6
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C-TERMINAL PART (RESIDUES 315-516) OF PORM WITH THE LLAMA NANOBODY NB130
Descriptor:T9SS component cytoplasmic membrane protein PorM, nb130
Authors:Leone, P., Cambillau, C., Roussel, A.
Deposit date:2017-11-10
Release date:2018-02-07
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.
Nat Commun, 9, 2018
2XB6
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REVISITED CRYSTAL STRUCTURE OF NEUREXIN1BETA-NEUROLIGIN4 COMPLEX
Descriptor:NEUROLIGIN-4, X-LINKED, NEUREXIN-1-BETA, ...
Authors:Leone, P., Comoletti, D., Ferracci, G., Conrod, S., Garcia, S.U., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2010-04-07
Release date:2010-06-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights Into the Exquisite Selectivity of Neurexin-Neuroligin Synaptic Interactions
Embo J., 29, 2010
1Z3Q
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RESOLUTION OF THE STRUCTURE OF THE ALLERGENIC AND ANTIFUNGAL BANANA FRUIT THAUMATIN-LIKE PROTEIN AT 1.7A
Descriptor:Thaumatin-like Protein, 1,2-ETHANEDIOL
Authors:Leone, P., Menu-Bouaouiche, L., Peumans, W.J., Barre, A., Payan, F., Roussel, A., Van Damme, E.J.M., Rouge, P.
Deposit date:2005-03-14
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Resolution of the structure of the allergenic and antifungal banana fruit thaumatin-like protein at 1.7-A
Biochimie, 88, 2006
2VU8
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CRYSTAL STRUCTURE OF AN INSECT INHIBITOR WITH A FUNGAL TRYPSIN
Descriptor:TRYPSIN, PACIFASTIN-RELATED SERINE PROTEASE INHIBITOR
Authors:Leone, P., Roussel, A., Kellenberger, C.
Deposit date:2008-05-21
Release date:2008-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Locusta Migratoria Protease Inhibitor 3 (Lmpi-3) in Complex with Fusarium Oxysporum Trypsin.
Acta Crystallogr.,Sect.D, 64, 2008
4MJT
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CRYSTAL STRUCTURE OF THE OLIGOMERIC PORE-FORMING TOXIN PRO-MONALYSIN
Descriptor:MONALYSIN, Monalysin, ZINC ION
Authors:Leone, P., Roussel, A.
Deposit date:2013-09-04
Release date:2015-03-11
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.
J.Biol.Chem., 290, 2015
4MKO
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CRYSTAL STRUCTURE OF THE MONOMERIC, CLEAVED FORM OF THE PORE-FORMING TOXIN MONALYSIN
Descriptor:Monalysin, MERCURY (II) ION, ZINC ION, ...
Authors:Leone, P., Roussel, A.
Deposit date:2013-09-05
Release date:2015-03-11
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.
J.Biol.Chem., 290, 2015
4MKQ
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CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN MONALYSIN MUTANT DELETED OF THE MEMBRANE-SPANNING DOMAIN
Descriptor:MONALYSIN, Monalysin
Authors:Leone, P., Roussel, A.
Deposit date:2013-09-05
Release date:2015-03-11
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.
J.Biol.Chem., 290, 2015
6EY4
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PERIPLASMIC DOMAIN (RESIDUES 36-513) OF GLDM
Descriptor:GldM, 1,2-ETHANEDIOL
Authors:Leone, P., Roche, J., Cambillau, C., Roussel, A.
Deposit date:2017-11-10
Release date:2018-02-07
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.
Nat Commun, 9, 2018
4MNS
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CRYSTAL STRUCTURE OF THE MAJOR POLLEN ALLERGEN BET V 1-A IN COMPLEX WITH P303
Descriptor:Major pollen allergen Bet v 1-A, (3R,4R,5aR,11aR)-3-methyl-6,11-dioxo-2,3,4,5,5a,6,11,11a-octahydrothiepino[3,2-g]isoquinoline-4-carboxylic acid
Authors:Leone, P., Roussel, A.
Deposit date:2013-09-11
Release date:2015-03-11
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen-allergic patients.
Allergy, 70, 2015
2RKQ
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CRYSTAL STRUCTURE OF DROSOPHILA PEPTIDOGLYCAN RECOGNITION PROTEIN SD (PGRP-SD)
Descriptor:Peptidoglycan-recognition protein-SD
Authors:Roussel, A., Royet, J., Leone, P., Kellenberger, C.
Deposit date:2007-10-17
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Drosophila PGRP-SD suggests binding to DAP-type but not lysine-type peptidoglycan
Mol.Immunol., 45, 2008
5FWO
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LLAMA NANOBODY PORM_130
Descriptor:NANOBODY
Authors:Leone, P., Roussel, A.
Deposit date:2016-02-18
Release date:2017-05-03
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5LMJ
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LLAMA NANOBODY PORM_19
Descriptor:nanobody, PHOSPHATE ION
Authors:Leone, P., Cambillau, C., Roussel, A.
Deposit date:2016-08-01
Release date:2017-05-03
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2WQZ
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CRYSTAL STRUCTURE OF SYNAPTIC PROTEIN NEUROLIGIN-4 IN COMPLEX WITH NEUREXIN-BETA 1: ALTERNATIVE REFINEMENT
Descriptor:NEUROLIGIN 4, X-LINKED, NEUREXIN-1-BETA, ...
Authors:Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2009-08-28
Release date:2009-09-08
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Analysis of the Synaptic Protein Neuroligin and its Beta-Neurexin Complex: Determinants for Folding and Cell Adhesion.
Neuron, 56, 2007
3BE8
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CRYSTAL STRUCTURE OF THE SYNAPTIC PROTEIN NEUROLIGIN 4
Descriptor:Neuroligin-4, X-linked, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2007-11-16
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of the Synaptic Protein Neuroligin and Its beta-Neurexin Complex: Determinants for Folding and Cell Adhesion
Neuron, 56, 2007
1TA3
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CRYSTAL STRUCTURE OF XYLANASE (GH10) IN COMPLEX WITH INHIBITOR (XIP)
Descriptor:xylanase inhibitor protein I, Endo-1,4-beta-xylanase, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Payan, F., Leone, P., Furniss, C., Tahir, T., Durand, A., Porciero, S., Manzanares, P., Williamson, G., Gilbert, H.J., Juge, N., Roussel, A.
Deposit date:2004-05-19
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Dual Nature of the Wheat Xylanase Protein Inhibitor XIP-I: STRUCTURAL BASIS FOR THE INHIBITION OF FAMILY 10 AND FAMILY 11 XYLANASES.
J.Biol.Chem., 279, 2004
1TE1
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CRYSTAL STRUCTURE OF FAMILY 11 XYLANASE IN COMPLEX WITH INHIBITOR (XIP-I)
Descriptor:xylanase inhibitor protein I, endo-1,4-xylanase, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Payan, F., Leone, P., Furniss, C., Tahir, T., Durand, A., Porciero, S., Manzanares, P., Williamson, G., Gilbert, H.J., Juge, N., Roussel, A.
Deposit date:2004-05-24
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Dual Nature of the Wheat Xylanase Protein Inhibitor XIP-I: STRUCTURAL BASIS FOR THE INHIBITION OF FAMILY 10 AND FAMILY 11 XYLANASES.
J.Biol.Chem., 279, 2004
2V8Q
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-13
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-20
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-23
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
1WO9
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SELECTIVE INHIBITION OF TRYPSINS BY INSECT PEPTIDES: ROLE OF P6-P10 LOOP
Descriptor:trypsin inhibitor
Authors:Kellenberger, C., Ferrat, G., Leone, P., Darbon, H., Roussel, A.
Deposit date:2004-08-12
Release date:2004-09-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Selective inhibition of trypsins by insect peptides: role of P6-P10 loop
Biochemistry, 42, 2003
2XXL
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CRYSTAL STRUCTURE OF DROSOPHILA GRASS CLIP SERINE PROTEASE OF TOLL PATHWAY
Descriptor:GRAM-POSITIVE SPECIFIC SERINE PROTEASE, ISOFORM B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kellenberger, C., Leone, P., Coquet, L., Jouenne, T., Reichhart, J.M., Roussel, A.
Deposit date:2010-11-10
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Function Analysis of Grass Clip Serine Protease Involved in Drosophila Toll Pathway Activation.
J.Biol.Chem., 286, 2011
2XZ4
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CRYSTAL STRUCTURE OF THE LFZ ECTODOMAIN OF THE PEPTIDOGLYCAN RECOGNITION PROTEIN LF
Descriptor:PEPTIDOGLYCAN-RECOGNITION PROTEIN LF, COPPER (II) ION, 1,2-ETHANEDIOL, ...
Authors:Basbous, N., Coste, F., Leone, P., Vincentelli, R., Royet, J., Kellenberger, C., Roussel, A.
Deposit date:2010-11-23
Release date:2011-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The Drosophila Peptidoglycan-Recognition Protein Lf Interacts with Peptidoglycan-Recognition Protein Lc to Downregulate the Imd Pathway.
Embo Rep., 12, 2011
2XZ8
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CRYSTAL STRUCTURE OF THE LFW ECTODOMAIN OF THE PEPTIDOGLYCAN RECOGNITION PROTEIN LF
Descriptor:PEPTIDOGLYCAN-RECOGNITION PROTEIN LF, TETRAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Basbous, N., Coste, F., Leone, P., Vincentelli, R., Royet, J., Kellenberger, C., Roussel, A.
Deposit date:2010-11-24
Release date:2011-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Drosophila Peptidoglycan-Recognition Protein Lf Interacts with Peptidoglycan-Recognition Protein Lc to Downregulate the Imd Pathway.
Embo Rep., 12, 2011
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