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1J6U
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CRYSTAL STRUCTURE OF UDP-N-ACETYLMURAMATE-ALANINE LIGASE MURC (TM0231) FROM THERMOTOGA MARITIMA AT 2.3 A RESOLUTION
Descriptor:UDP-N-acetylmuramate-alanine ligase MurC
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2002-08-29
Release date:2002-11-06
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution.
Proteins, 55, 2004
1J7J
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CRYSTAL STRUCTURE OF THE HPRT FROM SALMONELLA TYPHIMURIUM
Descriptor:hypoxanthine phosphoribosyltransferase, MAGNESIUM ION
Authors:Lee, C.C., Focia, P.J., Spraggon, G., Eakin, A.E.
Deposit date:2001-05-16
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the HPRT from Salmonella Typhimurium at 2.3 A Resolution
To be Published
1KEX
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CRYSTAL STRUCTURE OF THE B1 DOMAIN OF HUMAN NEUROPILIN-1
Descriptor:Neuropilin-1
Authors:Lee, C.C., Kreusch, A., McMullan, D., Ng, K., Spraggon, G.
Deposit date:2001-11-18
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
1LM4
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STRUCTURE OF PEPTIDE DEFORMYLASE FROM STAPHYLOCOCCUS AUREUS AT 1.45 A
Descriptor:peptide deformylase PDF1, FE (III) ION, GLYCEROL
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A.
Deposit date:2002-04-30
Release date:2003-06-24
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1LM6
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:peptide deformylase DEFB, FE (III) ION, GLYCEROL
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A.
Deposit date:2002-04-30
Release date:2003-06-24
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1LME
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM THERMOTOGA MARITIMA
Descriptor:peptide deformylase
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A., Joint Center for Structural Genomics (JCSG)
Deposit date:2002-05-01
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1N5N
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Peptide deformylase, ZINC ION, GLYCEROL
Authors:Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A.
Deposit date:2002-11-06
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1NH1
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CRYSTAL STRUCTURE OF THE TYPE III EFFECTOR AVRB FROM PSEUDOMONAS SYRINGAE.
Descriptor:Avirulence B protein
Authors:Lee, C.C., Wood, M.D., Ng, K., Luginbuhl, P., Spraggon, G., Katagiri, F.
Deposit date:2002-12-18
Release date:2004-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae.
Structure, 12, 2004
1S17
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IDENTIFICATION OF NOVEL POTENT BICYCLIC PEPTIDE DEFORMYLASE INHIBITORS
Descriptor:Peptide deformylase, NICKEL (II) ION, 2-(3,4-DIHYDRO-3-OXO-2H-BENZO[B][1,4]THIAZIN-2-YL)-N-HYDROXYACETAMIDE, ...
Authors:Molteni, V., He, X., Nabakka, J., Yang, K., Kreusch, A., Gordon, P., Bursulaya, B., Ryder, N.S., Goldberg, R., He, Y.
Deposit date:2004-01-05
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification of novel potent bicyclic peptide deformylase inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
1ZLT
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CRYSTAL STRUCTURE OF CHK1 COMPLEXED WITH A HYMENALDISINE ANALOG
Descriptor:Serine/threonine-protein kinase Chk1, SULFATE ION, (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE
Authors:Lee, C.C., Ng, K., Wan, Y., Gray, N., Spraggon, G.
Deposit date:2005-05-09
Release date:2006-06-27
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog
To be Published
2DF7
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CRYSTAL STRUCTURE OF INFECTIOUS BURSAL DISEASE VIRUS VP2 SUBVIRAL PARTICLE
Descriptor:structural polyprotein VP2, CHLORIDE ION, CALCIUM ION
Authors:Ko, T.P., Lee, C.C., Wang, M.Y., Wang, A.H.
Deposit date:2006-02-27
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: Implications in virion assembly and immunogenicity.
J.Struct.Biol., 155, 2006
2ETM
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CRYSTAL STRUCTURE OF FOCAL ADHESION KINASE DOMAIN COMPLEXED WITH 7H-PYRROLO [2,3-D] PYRIMIDINE DERIVATIVE
Descriptor:Focal adhesion kinase 1, 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE
Authors:Lee, C.C.
Deposit date:2005-10-27
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds
To be Published
2IJM
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CRYSTAL STRUCTURE OF FOCAL ADHESION KINASE DOMAIN WITH 2 MOLECULES IN THE ASYMMETRIC UNIT COMPLEXED WITH ADP AND ATP
Descriptor:Focal Adhesion Kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE
Authors:Lee, C.C.
Deposit date:2006-09-29
Release date:2007-08-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds
To be Published
2Z94
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH TDT
Descriptor:Replicase polyprotein 1ab, ZINC ION, 4-methylbenzene-1,2-dithiol
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-17
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors
Febs Lett., 581, 2007
2Z9G
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH PMA
Descriptor:3C-like proteinase, MERCURY (II) ION, BENZENE
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-19
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9J
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH EPDTC
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE, zinc(II)hydrogensulfide
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9K
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1600
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE, (dimethylamino)(hydroxy)zinc'
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9L
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1586
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE, diaminozinc
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2ZTX
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COMPLEX STRUCTURE OF CVB3 3C PROTEASE WITH EPDTC
Descriptor:3C proteinase, zinc(II)hydrogensulfide
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-10
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZTY
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM CVB3 IN SPACE GROUP C2
Descriptor:3C proteinase
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-10
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZTZ
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM CVB3 IN SPACE GROUP P21
Descriptor:3C proteinase
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-11
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU1
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CRYSTAL STRUCTURE OF CVB3 3C PROTEASE MUTANT C147A
Descriptor:3C proteinase
Authors:Lee, C.C., Tsui, Y.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU2
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COMPLEX STRUCTURE OF COV 229E 3CL PROTEASE WITH EPDTC
Descriptor:3C-like proteinase, (4S)-2-METHYL-2,4-PENTANEDIOL, zinc(II)hydrogensulfide
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU3
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COMPLEX STRUCTURE OF CVB3 3C PROTEASE WITH TG-0204998
Descriptor:3C proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide
Authors:Lee, C.C., Tsui, Y.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU4
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COMPLEX STRUCTURE OF SARS-COV 3CL PROTEASE WITH TG-0204998
Descriptor:3C-like proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide
Authors:Hsu, M.F., Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
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