Author results

1FAS
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1.9 ANGSTROM RESOLUTION STRUCTURE OF FASCICULIN 1, AN ANTI-ACETYLCHOLINESTERASE TOXIN FROM GREEN MAMBA SNAKE VENOM
Descriptor:FASCICULIN 1
Authors:Le Du, M.H., Marchot, P., Bougis, P.E., Fontecilla-Camps, J.C.
Deposit date:1992-08-07
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.9-A resolution structure of fasciculin 1, an anti-acetylcholinesterase toxin from green mamba snake venom.
J.Biol.Chem., 267, 1992
1EW2
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CRYSTAL STRUCTURE OF A HUMAN PHOSPHATASE
Descriptor:PHOSPHATASE, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Le Du, M.H., Stigbrand, T., Taussig, M.J., Menez, A., Stura, E.A.
Deposit date:2000-04-21
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.
J.Biol.Chem., 276, 2001
1KH4
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E. COLI ALKALINE PHOSPHATASE MUTANT (D330N) IN COMPLEX WITH PHOSPHATE
Descriptor:ALKALINE PHOSPHATASE, ZINC ION, MAGNESIUM ION, ...
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E.
Deposit date:2001-11-29
Release date:2002-03-27
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KH5
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E. COLI ALKALINE PHOSPHATASE MUTANT (D330N) MIMIC OF THE TRANSITION STATES WITH ALUMINIUM FLUORIDE
Descriptor:ALKALINE PHOSPHATASE, ZINC ION, MAGNESIUM ION, ...
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E.
Deposit date:2001-11-29
Release date:2002-03-13
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KH7
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153GD330N)
Descriptor:alkaline phosphatase, ZINC ION, MAGNESIUM ION, ...
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E.
Deposit date:2001-11-29
Release date:2002-03-27
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KH9
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153GD330N) COMPLEX WITH PHOSPHATE
Descriptor:Alkaline phosphatase, ZINC ION, MAGNESIUM ION, ...
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E.
Deposit date:2001-11-29
Release date:2002-03-13
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHJ
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N) MIMIC OF THE TRANSITION STATES WITH ALUMINIUM FLUORIDE
Descriptor:Alkaline phosphatase, ZINC ION, ALUMINUM FLUORIDE
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E., Menez, A., Boulain, J.C.
Deposit date:2001-11-30
Release date:2002-03-13
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHK
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N)
Descriptor:Alkaline Phosphatase, ZINC ION, MAGNESIUM ION
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E., Menez, A., Boulain, J.C.
Deposit date:2001-11-30
Release date:2002-03-13
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHL
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N) COMPLEX WITH PHOSPHATE
Descriptor:Alkaline Phosphatase, ZINC ION, PHOSPHATE ION
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E., Menez, A., Boulain, J.C.
Deposit date:2001-11-30
Release date:2002-03-13
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHN
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N) ZINC FORM
Descriptor:Alkaline phosphatase, ZINC ION
Authors:Le Du, M.H., Lamoure, C., Muller, B.H., Bulgakov, O.V., Lajeunesse, E., Menez, A., Boulain, J.C.
Deposit date:2001-11-30
Release date:2002-03-13
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1QM7
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X-RAY STRUCTURE OF A THREE-FINGERED CHIMERIC PROTEIN, STABILITY OF A STRUCTURAL SCAFFOLD
Descriptor:R-CHII
Authors:Le Du, M.H., Ricciardi, A., Khayati, M., Menez, R., Boulain, J.C., Menez, A., Ducancel, F.
Deposit date:1999-09-21
Release date:2000-03-15
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stability of a Structural Scaffold Upon Activity Transfer : X-Ray Structure of a Three Fingers Chimeric Protein.
J.Mol.Biol., 296, 2000
1FSC
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CRYSTAL STRUCTURE OF FASCICULIN 2 FROM GREEN MAMBA SNAKE VENOM: EVIDENCE FOR UNUSUAL LOOP FLEXIBILITY
Descriptor:FASCICULIN 2, UNKNOWN LIGAND
Authors:Housset, D., Le Du, M.H., Fontecilla-Camps, J.C.
Deposit date:1995-03-27
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility.
Acta Crystallogr.,Sect.D, 52, 1996
1FF4
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X-RAY STRUCTURE OF MUSCARINIC TOXIN 2 AT 1.5 ANGSTROM RESOLUTION
Descriptor:MUSCARINIC TOXIN/ACETYLCHOLINE RECEPTOR BINDING PROTEIN, SULFATE ION
Authors:Menez, R., Le Du, M.H., Gaucher, J.F., Menez, A.
Deposit date:2000-07-25
Release date:2003-07-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray structure of muscarinic toxin 2 at 1.5 Angstrom resolution
To be Published
1GZE
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STRUCTURE OF THE CLOSTRIDIUM BOTULINUM C3 EXOENZYME (L177C MUTANT)
Descriptor:MONO-ADP-RIBOSYLTRANSFERASE C3, MERCURY (II) ION
Authors:Menetrey, J., Flatau, G., Stura, E.A., Charbonnier, J.B., Gas, F., Teulon, J.M., Le Du, M.H., Boquet, P., Menez, A.
Deposit date:2002-05-21
Release date:2002-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Nad Binding Induces Conformational Changes in Rho Adp-Ribosylating Clostridium Botulinum C3 Exoenzyme
J.Biol.Chem., 277, 2002
1GZF
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STRUCTURE OF THE CLOSTRIDIUM BOTULINUM C3 EXOENZYME (WILD-TYPE) IN COMPLEX WITH NAD
Descriptor:MONO-ADP-RIBOSYLTRANSFERASE C3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Menetrey, J., Flatau, G., Stura, E.A., Charbonnier, J.B., Gas, F., Teulon, J.M., Le Du, M.H., Boquet, P., Menez, A.
Deposit date:2002-05-21
Release date:2002-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Nad Binding Induces Conformational Changes in Rho Adp-Ribosylating Clostridium Botulinum C3 Exoenzyme
J.Biol.Chem., 277, 2002
1IQ9
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CRYSTAL STRUCTURE AT 1.8 A OF TOXIN A FROM NAJA NIGRICOLLIS VENOM
Descriptor:alpha-neurotoxin, SULFATE ION
Authors:Menez, R., Le Du, M.H., Menez, A.
Deposit date:2001-07-10
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Motions and structural variability within toxins: Implication for their use as scaffolds for protein engineering
Protein Sci., 12, 2003
1RCN
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CRYSTAL STRUCTURE OF THE RIBONUCLEASE A D(APTPAPAPG) COMPLEX : DIRECT EVIDENCE FOR EXTENDED SUBSTRATE RECOGNITION
Descriptor:DNA (5'-D(*AP*TP*AP*A)-3'), PROTEIN (RIBONUCLEASE A (E.C.3.1.27.5))
Authors:Fontecilla-Camps, J.C., De Llorens, R., Le Du, M.H., Cuchillo, C.M.
Deposit date:1994-05-27
Release date:1994-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition.
J.Biol.Chem., 269, 1994
1YNT
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STRUCTURE OF THE MONOMERIC FORM OF T. GONDII SAG1 SURFACE ANTIGEN BOUND TO A HUMAN FAB
Descriptor:4F11E12 Fab variable light chain region, 4F11E12 Fab variable heavy chain region, protein L, ...
Authors:Graille, M., Stura, E.A., Bossus, M., Muller, B.H., Letourneur, O., Battail-Poirot, N., Sibai, G., Rolland, D., Le Du, M.H., Ducancel, F.
Deposit date:2005-01-25
Release date:2005-12-27
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response
J.Mol.Biol., 354, 2005
1YWH
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CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR
Descriptor:Urokinase plasminogen activator surface receptor, antagonist peptide, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Llinas, P., Le Du, M.H., Gardsvoll, H., Dano, K., Ploug, M., Gilquin, B., Stura, E.A., Menez, A.
Deposit date:2005-02-18
Release date:2005-05-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
EMBO J., 24, 2005
1ZEB
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X-RAY STRUCTURE OF ALKALINE PHOSPHATASE FROM HUMAN PLACENTA IN COMPLEX WITH 5'-AMP
Descriptor:Alkaline phosphatase, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Llinas, P., Stura, E.A., Menez, A., Kiss, Z., Stigbrand, T., Millan, J.L., Le Du, M.H.
Deposit date:2005-04-18
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
J.Mol.Biol., 350, 2005
1ZED
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ALKALINE PHOSPHATASE FROM HUMAN PLACENTA IN COMPLEX WITH P-NITROPHENYL-PHOSPHONATE
Descriptor:Alkaline phosphatase, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Llinas, P., Stura, E.A., Menez, A., Kiss, Z., Stigbrand, T., Millan, J.L., Le Du, M.H.
Deposit date:2005-04-18
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
J.Mol.Biol., 350, 2005
1ZEF
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STRUCTURE OF ALKALINE PHOSPHATASE FROM HUMAN PLACENTA IN COMPLEX WITH ITS UNCOMPETITIVE INHIBITOR L-PHE
Descriptor:Alkaline phosphatase, N-ACETYL-D-GLUCOSAMINE, PHENYLALANINE, ...
Authors:Llinas, P., Stura, E.A., Menez, A., Kiss, Z., Stigbrand, T., Millan, J.L., Le Du, M.H.
Deposit date:2005-04-18
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
J.Mol.Biol., 350, 2005
2GLQ
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X-RAY STRUCTURE OF HUMAN ALKALINE PHOSPHATASE IN COMPLEX WITH STRONTIUM
Descriptor:Alkaline phosphatase, placental type, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Llinas, P., Masella, M., Stigbrand, T., Menez, A., Stura, E.A., Le Du, M.H.
Deposit date:2006-04-05
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural studies of human alkaline phosphatase in complex with strontium: Implication for its secondary effect in bones.
Protein Sci., 15, 2006
2H7Z
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CRYSTAL STRUCTURE OF IRDITOXIN
Descriptor:Irditoxin subunit A, Irditoxin subunit B
Authors:Pawlak, J., Kini, R.M., Stura, E.A., Le Du, M.H.
Deposit date:2006-06-06
Release date:2006-08-29
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.
Faseb J., 23, 2009
2HEO
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GENERAL STRUCTURE-BASED APPROACH TO THE DESIGN OF PROTEIN LIGANDS: APPLICATION TO THE DESIGN OF KV1.2 POTASSIUM CHANNEL BLOCKERS.
Descriptor:5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1
Authors:Magis, C., Gasparini, S., Charbonnier, J.B., Stura, E., Le Du, M.H., Menez, A., Cuniasse, P.
Deposit date:2006-06-21
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
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