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3L79
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CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE DK1 COMPLEX
Descriptor:Glycogen phosphorylase, muscle form, 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione
Authors:Tsirkone, V.G., Lamprakis, C., Hayes, J.M., Skamnaki, V., Drakou, C., Zographos, S.E., Leonidas, D.D.
Deposit date:2009-12-28
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
Bioorg.Med.Chem., 18, 2010
3L7A
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CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE DK2 COMPLEX
Descriptor:Glycogen phosphorylase, muscle form, 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)-4-[(phenylcarbonyl)amino]pyrimidin-2(1H)-one
Authors:Tsirkone, V.G., Lamprakis, C., Hayes, J.M., Skamnaki, V., Drakou, C., Zographos, S.E., Leonidas, D.D.
Deposit date:2009-12-28
Release date:2010-10-20
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
Bioorg.Med.Chem., 18, 2010
3L7B
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CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE DK3 COMPLEX
Descriptor:Glycogen phosphorylase, muscle form, 4-amino-1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)pyrimidin-2(1H)-one
Authors:Tsirkone, V.G., Lamprakis, C., Hayes, J.M., Skamnaki, V., Drakou, C., Zographos, S.E., Leonidas, D.D.
Deposit date:2009-12-28
Release date:2010-10-20
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
Bioorg.Med.Chem., 18, 2010
3L7C
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CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE DK4 COMPLEX
Descriptor:Glycogen phosphorylase, muscle form, 1-(3-deoxy-3-fluoro-beta-D-glucopyranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
Authors:Tsirkone, V.G., Lamprakis, C., Hayes, J.M., Skamnaki, V., Drakou, C., Zographos, S.E., Leonidas, D.D.
Deposit date:2009-12-28
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
Bioorg.Med.Chem., 18, 2010
3L7D
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CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE DK5 COMPLEX
Descriptor:Glycogen phosphorylase, muscle form, 1-(2,3-dideoxy-3-fluoro-beta-D-arabino-hexopyranosyl)-4-[(phenylcarbonyl)amino]pyrimidin-2(1H)-one
Authors:Tsirkone, V.G., Lamprakis, C., Hayes, J.M., Skamnaki, V., Drakou, C., Zographos, S.E., Leonidas, D.D.
Deposit date:2009-12-28
Release date:2010-10-20
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
Bioorg.Med.Chem., 18, 2010
4OMJ
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CRYSTAL STRUCTURE OF SPF BOUND TO 2,3-OXIDOSQUALENE
Descriptor:SEC14-like protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Christen, M., Marcaida, M.J., Lamprakis, C., Cascella, M., Stocker, A.
Deposit date:2014-01-27
Release date:2015-04-15
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190, 2015
4OMK
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CRYSTAL STRUCTURE OF SPF BOUND TO SQUALENE
Descriptor:SEC14-like protein 2, SULFATE ION, CHLORIDE ION, ...
Authors:Christen, M., Marcaida, M.J., Lamprakis, C., Cascella, M., Stocker, A.
Deposit date:2014-01-27
Release date:2015-04-15
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190, 2015
3SYM
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH 3 -C-(HYDROXYMETHYL)-BETA-D-GLUCOPYRANONUCLEOSIDE OF 5-FLUOROURACIL
Descriptor:Glycogen phosphorylase, muscle form, 5-fluoro-1-[3-C-(hydroxymethyl)-beta-D-glucopyranosyl]pyrimidine-2,4(1H,3H)-dione
Authors:Skamnaki, V.T., Katsandi, A.L., Kontou, M., Leonidas, D.D.
Deposit date:2011-07-18
Release date:2012-02-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3'-Axial CH(2) OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest Why.
Chem.Biol.Drug Des., 79, 2012
3SYR
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH BETA-D-GLUCOPYRANONUCLEOSIDE 5-FLUOROURACIL
Descriptor:Glycogen phosphorylase, muscle form, 5-fluoro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione
Authors:Skamnaki, V.T., Kantsadi, A.L., Kontou, M., Leonidas, D.D.
Deposit date:2011-07-18
Release date:2012-02-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3'-Axial CH(2) OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest Why.
Chem.Biol.Drug Des., 79, 2012