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PDGF-B blocking antibody bound to PDGF-BB
Descriptor:	Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain
Authors:	Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G.
Deposit date:	2014-05-12
Release date:	2015-03-11
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta. Biochemistry, 54, 2015

Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate
Authors:	Wei, J, Tong, L.
Deposit date:	2019-02-16
Release date:	2019-04-17
Last modified:	2024-03-20
Method:	ELECTRON MICROSCOPY (3.67 Å)
Cite:	An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Nature, 568, 2019