Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1NTP
DownloadVisualize
BU of 1ntp by Molmil
USE OF THE NEUTRON DIFFRACTION H/D EXCHANGE TECHNIQUE TO DETERMINE THE CONFORMATIONAL DYNAMICS OF TRYPSIN
Descriptor: BETA-TRYPSIN, PHOSPHORYLISOPROPANE
Authors:Kossiakoff, A.A.
Deposit date:1987-09-16
Release date:1988-01-16
Last modified:2024-10-30
Method:NEUTRON DIFFRACTION (1.8 Å)
Cite:Use of the neutron diffraction--H/D exchange technique to determine the conformational dynamics of trypsin
Basic Life Sci., 27, 1984
1TGN
DownloadVisualize
BU of 1tgn by Molmil
STRUCTURE OF BOVINE TRYPSINOGEN AT 1.9 ANGSTROMS RESOLUTION
Descriptor: TRYPSINOGEN
Authors:Kossiakoff, A.A, Stroud, R.M.
Deposit date:1979-09-19
Release date:1979-10-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of bovine trypsinogen at 1.9 A resolution.
Biochemistry, 16, 1977
3PGF
DownloadVisualize
BU of 3pgf by Molmil
Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)
Descriptor: GLYCEROL, IMIDAZOLE, Maltose-binding periplasmic protein, ...
Authors:Kossiakoff, A.A, Duguid, E.M, Sandstrom, A.
Deposit date:2010-11-01
Release date:2011-03-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Nat.Struct.Mol.Biol., 18, 2011
8RQF
DownloadVisualize
BU of 8rqf by Molmil
Cryo-EM structure of human NTCP-Bulevirtide complex
Descriptor: Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ...
Authors:Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P.
Deposit date:2024-01-18
Release date:2024-03-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP.
Nat Commun, 15, 2024
5UEA
DownloadVisualize
BU of 5uea by Molmil
Structure of antigen-Fab complex with Histone chaperone ASF1
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2016-12-29
Release date:2018-01-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
7RTH
DownloadVisualize
BU of 7rth by Molmil
Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab "NabFab"
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fragment Antigen-Binding Heavy Chain, ...
Authors:Filippova, E.V, Mukherjee, S, Bloch, J.S, Locher, K.P, Kossiakoff, A.A.
Deposit date:2021-08-13
Release date:2021-09-01
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PHP
DownloadVisualize
BU of 7php by Molmil
Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM
Descriptor: Anti-Fab nanobody, Multidrug resistance protein NorM, NabFab HC, ...
Authors:Bloch, J.S, Mukherjee, S, Kowal, J, Niederer, M, Pardon, E, Steyaert, J, Kossiakoff, A.A, Locher, K.P.
Deposit date:2021-08-18
Release date:2021-09-01
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PIJ
DownloadVisualize
BU of 7pij by Molmil
Structure of Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM
Descriptor: Anti-Fab nanobody, DMTNb16_4, Divalent metal cation transporter MntH, ...
Authors:Bloch, J.S, Mukherjee, S, Kowal, J, Kossiakoff, A.A, Locher, K.P.
Deposit date:2021-08-20
Release date:2021-09-01
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PHQ
DownloadVisualize
BU of 7phq by Molmil
Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM
Descriptor: Anti-Fab nanobody, DMT-Nb16_4, Divalent metal cation transporter MntH, ...
Authors:Bloch, J.S, Mukherjee, S, Kowal, J, Kossiakoff, A.A, Locher, K.P.
Deposit date:2021-08-18
Release date:2021-09-01
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (8.45 Å)
Cite:Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
9AVO
DownloadVisualize
BU of 9avo by Molmil
The crystal structure of an engineered Protein GD with Human Kappa Fab
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1, ...
Authors:Slezak, T, Kossiakoff, A.A.
Deposit date:2024-03-04
Release date:2025-02-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Engineered protein G variants for multifunctional antibody-based assemblies.
Protein Sci., 34, 2025
9AWE
DownloadVisualize
BU of 9awe by Molmil
The crystal structure of an engineered Protein GF with Human Kappa Fab
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1, ...
Authors:Slezak, T, Kossiakoff, A.A.
Deposit date:2024-03-05
Release date:2025-02-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Engineered protein G variants for multifunctional antibody-based assemblies.
Protein Sci., 34, 2025
5CWW
DownloadVisualize
BU of 5cww by Molmil
Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD complex
Descriptor: Nucleoporin NUP145N, Nucleoporin NUP159, Nucleoporin NUP82
Authors:Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWV
DownloadVisualize
BU of 5cwv by Molmil
Crystal structure of Chaetomium thermophilum Nup192 TAIL domain
Descriptor: Nucleoporin NUP192
Authors:Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.155 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWU
DownloadVisualize
BU of 5cwu by Molmil
Crystal structure of Chaetomium thermophilum Nup188 TAIL domain
Descriptor: GLYCEROL, Nucleoporin NUP188
Authors:Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5UCB
DownloadVisualize
BU of 5ucb by Molmil
Structure of antigen-Fab complex with engineered switch residue region.
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
Deposit date:2016-12-22
Release date:2017-12-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
3BOG
DownloadVisualize
BU of 3bog by Molmil
Snow Flea Antifreeze Protein Quasi-racemate
Descriptor: 6.5 kDa glycine-rich antifreeze protein, UNKNOWN LIGAND
Authors:Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M.
Deposit date:2007-12-17
Release date:2008-09-23
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers
J.Am.Chem.Soc., 130, 2008
3BOI
DownloadVisualize
BU of 3boi by Molmil
Snow Flea Antifreeze Protein Racemate
Descriptor: 6.5 kDa glycine-rich antifreeze protein
Authors:Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M.
Deposit date:2007-12-17
Release date:2008-09-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers
J.Am.Chem.Soc., 130, 2008
7ZLH
DownloadVisualize
BU of 7zlh by Molmil
Cryo-EM structure of C-mannosyltransferase CeDPY19, in apo state, bound to CMT2-Fab and anti-Fab nanobody
Descriptor: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
Authors:Bloch, J.S, Mukherjee, S, Irobalieva, R, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
Deposit date:2022-04-15
Release date:2023-01-11
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
7ZLG
DownloadVisualize
BU of 7zlg by Molmil
Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with acceptor peptide and bound to CMT2-Fab and anti-Fab nanobody
Descriptor: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
Authors:Bloch, J.S, Mukherjee, S, Mao, R, Irobalieva, R, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
Deposit date:2022-04-15
Release date:2023-01-11
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
7ZLJ
DownloadVisualize
BU of 7zlj by Molmil
Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody
Descriptor: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
Authors:Bloch, J.S, Mao, R, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
Deposit date:2022-04-15
Release date:2023-01-11
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
7ZLI
DownloadVisualize
BU of 7zli by Molmil
Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody
Descriptor: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
Authors:Bloch, J.S, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
Deposit date:2022-04-15
Release date:2023-01-11
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
7ZYI
DownloadVisualize
BU of 7zyi by Molmil
Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody
Descriptor: CHOLESTEROL, GLYCOCHENODEOXYCHOLIC ACID, Nanobody, ...
Authors:Liu, H, Irobalieva, R.N, Bang-Sorensen, R, Nosol, K, Mukherjee, S, Agrawal, P, Stieger, B, Kossiakoff, A.A, Locher, K.P.
Deposit date:2022-05-24
Release date:2022-07-13
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
Cell Res., 32, 2022
8PG0
DownloadVisualize
BU of 8pg0 by Molmil
Human OATP1B3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHOLESTEROL, ...
Authors:Ciuta, A.-D, Nosol, K, Kowal, J, Mukherjee, S, Ramirez, A.S, Stieger, B, Kossiakoff, A.A, Locher, K.P.
Deposit date:2023-06-17
Release date:2023-09-27
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structure of human drug transporters OATP1B1 and OATP1B3.
Nat Commun, 14, 2023
8PHW
DownloadVisualize
BU of 8phw by Molmil
Human OATP1B1
Descriptor: CHOLESTEROL HEMISUCCINATE, Fab18 (heavy chain, variable region), ...
Authors:Ciuta, A.-D, Nosol, K, Kowal, J, Mukherjee, S, Ramirez, A.S, Stieger, B, Kossiakoff, A.A, Locher, K.P.
Deposit date:2023-06-20
Release date:2023-09-27
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of human drug transporters OATP1B1 and OATP1B3.
Nat Commun, 14, 2023
6RLX
DownloadVisualize
BU of 6rlx by Molmil
X-RAY STRUCTURE OF HUMAN RELAXIN AT 1.5 ANGSTROMS. COMPARISON TO INSULIN AND IMPLICATIONS FOR RECEPTOR BINDING DETERMINANTS
Descriptor: RELAXIN, A-CHAIN, B-CHAIN
Authors:Eigenbrot, C, Randal, M, Kossiakoff, A.A.
Deposit date:1991-06-21
Release date:1993-10-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants.
J.Mol.Biol., 221, 1991

238582

PDB entries from 2025-07-09

PDB statisticsPDBj update infoContact PDBjnumon