8PHW

Human OATP1B1

Summary for 8PHW

• Entry DOI: 10.2210/pdb8phw/pdb
• Related: 8PG0
• EMDB information: 17677
• Descriptor: Solute carrier organic anion transporter family member 1B1, Fab18 (heavy chain, variable region), Fab18 (light chain, variable region), ... (5 entities in total)
• Functional Keywords: organic anion, e1s, e-3-s, estrone-3-sulphate, slco1b1, uptake, drug, transporter, polypeptide, liver, hepatocyte, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 124989.38

Authors

Ciuta, A.-D.,Nosol, K.,Kowal, J.,Mukherjee, S.,Ramirez, A.S.,Stieger, B.,Kossiakoff, A.A.,Locher, K.P. (deposition date: 2023-06-20, release date: 2023-09-27, Last modification date: 2024-03-20)

• Primary citation: Ciuta, A.D.,Nosol, K.,Kowal, J.,Mukherjee, S.,Ramirez, A.S.,Stieger, B.,Kossiakoff, A.A.,Locher, K.P.; Structure of human drug transporters OATP1B1 and OATP1B3.; Nat Commun, 14:5774-5774, 2023; PubMed: 37723174; DOI: 10.1038/s41467-023-41552-8

Experimental method

ELECTRON MICROSCOPY (3.6 Å)