Author results

1FU3
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THREE-DIMENSIONAL STRUCTURE IN SOLUTION OF THE SODIUM CHANNEL AGONIST/ANTAGONIST DELTA-CONOTOXIN TXVIA
Descriptor:DELTA-CONOTOXIN TXVIA
Authors:Kohno, T., Sasaki, T., Fainzilber, M., Sato, K.
Deposit date:2000-09-14
Release date:2002-09-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the sodium channel agonist/antagonist delta-conotoxin TxVIA.
J.Biol.Chem., 277, 2002
1OMG
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NMR STUDY OF OMEGA-CONOTOXIN MVIIA
Descriptor:OMEGA-CONOTOXIN MVIIA
Authors:Kohno, T., Kim, J.-I., Kobayashi, K., Kodera, Y., Maeda, T., Sato, K.
Deposit date:1995-04-26
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure in solution of the calcium channel blocker omega-conotoxin MVIIA.
Biochemistry, 34, 1995
1QCM
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AMYLOID BETA PEPTIDE (25-35), NMR, 20 STRUCTURES
Descriptor:AMYLOID BETA PEPTIDE
Authors:Kohno, T., Kobayashi, K., Maeda, T., Sato, K., Takashima, A.
Deposit date:1996-07-19
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structures of the amyloid beta peptide (25-35) in membrane-mimicking environment.
Biochemistry, 35, 1996
1V5A
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SOLUTION STRUCTURE OF COVALITOXIN I
Descriptor:Covalitoxin-I
Authors:Kohno, T., Sasaki, T., Sato, K.
Deposit date:2003-11-21
Release date:2005-03-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Covalitoxin I
To be Published
2D1N
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COLLAGENASE-3 (MMP-13) COMPLEXED TO A HYDROXAMIC ACID INHIBITOR
Descriptor:Collagenase 3, ZINC ION, CALCIUM ION, ...
Authors:Kohno, T., Hochigai, H., Yamashita, E., Tsukihara, T., Kanaoka, M.
Deposit date:2005-08-29
Release date:2006-06-27
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453
Biochem.Biophys.Res.Commun., 344, 2006
2D1O
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STROMELYSIN-1 (MMP-3) COMPLEXED TO A HYDROXAMIC ACID INHIBITOR
Descriptor:Stromelysin-1, ZINC ION, CALCIUM ION, ...
Authors:Kohno, T., Hochigai, H., Yamashita, E., Tsukihara, T., Kanaoka, M.
Deposit date:2005-08-30
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453
Biochem.Biophys.Res.Commun., 344, 2006
4PK5
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CRYSTAL STRUCTURE OF THE INDOLEAMINE 2,3-DIOXYGENAGSE 1 (IDO1) COMPLEXED WITH AMG-1
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, N-(1,3-benzodioxol-5-yl)-2-{[5-(4-methylphenyl)[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl]sulfanyl}acetamide
Authors:Kohno, T., Tojo, S., Ishii, T.
Deposit date:2014-05-13
Release date:2014-09-03
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Crystal Structures and Structure-Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors.
Acs Med.Chem.Lett., 5, 2014
4PK6
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CRYSTAL STRUCTURE OF THE INDOLEAMINE 2,3-DIOXYGENAGSE 1 (IDO1) COMPLEXED WITH IMIDAZOTHIAZOLE DERIVATIVE
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, N-[2-(3-chlorophenyl)ethyl]-3-(4-methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carboxamide
Authors:Kohno, T., Tojo, S., Ishii, T., Kamioka, S.
Deposit date:2014-05-13
Release date:2014-09-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Crystal Structures and Structure-Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors.
Acs Med.Chem.Lett., 5, 2014
2D51
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PENTAKETIDE CHROMONE SYNTHASE (M207G MUTANT)
Descriptor:pentaketide chromone synthase
Authors:Kohno, T., Morita, H.
Deposit date:2005-10-27
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insight into Chain-Length Control and Product Specificity of Pentaketide Chromone Synthase from Aloe arborescens
Chem.Biol., 14, 2007
2D52
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PENTAKETIDE CHROMONE SYNTHASE (M207G MUTANT COMPLEXED WITH COA)
Descriptor:pentaketide chromone synthase, COENZYME A
Authors:Kohno, T., Morita, H.
Deposit date:2005-10-27
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insight into Chain-Length Control and Product Specificity of Pentaketide Chromone Synthase from Aloe arborescens
Chem.Biol., 14, 2007
1J1B
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BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH AMPPNP
Descriptor:Glycogen synthase kinase-3 beta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Kohno, T., Sugio, S., Matsuzaki, T.
Deposit date:2002-12-03
Release date:2003-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
1J1C
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BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH ADP
Descriptor:Glycogen synthase kinase-3 beta, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Kohno, T., Sugio, S., Matsuzaki, T.
Deposit date:2002-12-03
Release date:2003-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
1J1J
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CRYSTAL STRUCTURE OF HUMAN TRANSLIN
Descriptor:Translin
Authors:Sugiura, I., Sasaki, C., Hasegawa, T., Kohno, T., Sugio, S., Moriyama, H., Kasai, M., Matsuzaki, T.
Deposit date:2002-12-06
Release date:2003-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human translin at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1NC8
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HIGH-RESOLUTION SOLUTION NMR STRUCTURE OF THE MINIMAL ACTIVE DOMAIN OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE-2 NUCLEOCAPSID PROTEIN, 15 STRUCTURES
Descriptor:NUCLEOCAPSID PROTEIN, ZINC ION
Authors:Kodera, Y., Sato, K., Tsukahara, T., Komatsu, H., Maeda, T., Kohno, T.
Deposit date:1998-05-14
Release date:1999-05-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-resolution solution NMR structure of the minimal active domain of the human immunodeficiency virus type-2 nucleocapsid protein.
Biochemistry, 37, 1998
2DI2
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NMR STRUCTURE OF THE HIV-2 NUCLEOCAPSID PROTEIN
Descriptor:Nucleocapsid protein p7, ZINC ION
Authors:Matsui, T., Kodera, Y., Endoh, H., Miyauchi, E., Komatsu, H., Sato, K., Tanaka, T., Kohno, T., Maeda, T.
Deposit date:2006-03-27
Release date:2007-03-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:RNA Recognition Mechanism of the Minimal Active Domain of the Human Immunodeficiency Virus Type-2 Nucleocapsid Protein
J.Biochem.(Tokyo), 141, 2007
2E1X
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NMR STRUCTURE OF THE HIV-2 NUCLEOCAPSID PROTEIN
Descriptor:Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION
Authors:Matsui, T., Kodera, Y., Miyauchi, E., Tanaka, H., Endoh, H., Komatsu, H., Tanaka, T., Kohno, T., Maeda, T.
Deposit date:2006-11-03
Release date:2007-06-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural role of the secondary active domain of HIV-2 NCp8 in multi-functionality
Biochem.Biophys.Res.Commun., 358, 2007
2EC7
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SOLUTION STRUCTURE OF HUMAN IMMUNODIFICIENCY VIRUS TYPE-2 NUCLEOCAPSID PROTEIN
Descriptor:Gag polyprotein (Pr55Gag), ZINC ION
Authors:Matsui, T., Kodera, Y., Tanaka, T., Endoh, H., Tanaka, H., Miyauchi, E., Komatsu, H., Kohno, T., Maeda, T.
Deposit date:2007-02-10
Release date:2008-02-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7
Biochemistry, 48, 2009
2MLO
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HUMAN CCR2 MEMBRANE-PROXIMAL C-TERMINAL REGION (PRO-C) IN A MEMBRANE BOUND FORM
Descriptor:MCP-1 receptor
Authors:Esaki, K., Yoshinaga, S., Tsuji, T., Toda, E., Terashima, Y., Saitoh, T., Kohda, D., Kohno, T., Osawa, M., Ueda, T., Shimada, I., Matsushima, K., Terasawa, H.
Deposit date:2014-03-04
Release date:2014-10-08
Last modified:2014-10-29
Method:SOLUTION NMR
Cite:Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT
Febs J., 2014
2MLQ
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HUMAN CCR2 MEMBRANE-PROXIMAL C-TERMINAL REGION (PRO-C) IN A FROUNT BOUND FORM
Descriptor:MCP-1 receptor
Authors:Esaki, K., Yoshinaga, S., Tsuji, T., Toda, E., Terashima, Y., Saitoh, T., Kohda, D., Kohno, T., Osawa, M., Ueda, T., Shimada, I., Matsushima, K., Terasawa, H.
Deposit date:2014-03-04
Release date:2014-10-08
Last modified:2014-10-29
Method:SOLUTION NMR
Cite:Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT
Febs J., 2014
2RRN
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SOLUTION STRUCTURE OF SECDF PERIPLASMIC DOMAIN P4
Descriptor:Probable SecDF protein-export membrane protein
Authors:Tanaka, T., Tsukazaki, T., Echizen, Y., Nureki, O., Kohno, T.
Deposit date:2011-01-30
Release date:2011-05-18
Last modified:2011-12-28
Method:SOLUTION NMR
Cite:Structure and function of a membrane component SecDF that enhances protein export
Nature, 474, 2011
3AQP
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CRYSTAL STRUCTURE OF SECDF, A TRANSLOCON-ASSOCIATED MEMBRANE PROTEIN, FROM THERMUS THRMOPHILUS
Descriptor:Probable SecDF protein-export membrane protein
Authors:Tsukazaki, T., Mori, H., Echizen, Y., Ishitani, R., Fukai, S., Tanaka, T., Perederina, A., Vassylyev, D.G., Kohno, T., Ito, K., Nureki, O.
Deposit date:2010-11-16
Release date:2011-05-18
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and function of a membrane component SecDF that enhances protein export
Nature, 474, 2011
4ZKF
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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 12
Descriptor:2',5'-phosphodiesterase 12, MAGNESIUM ION
Authors:Kim, S.Y., Kohno, T., Mori, T., Kitano, K., Hakoshima, T.
Deposit date:2015-04-30
Release date:2015-06-17
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of human phosphodiesterase
To Be Published
1A13
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G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES
Descriptor:MASTOPARAN-X
Authors:Kusunoki, H., Wakamatsu, K., Sato, K., Miyazawa, T., Kohno, T.
Deposit date:1997-12-20
Release date:1999-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:G protein-bound conformation of mastoparan-X: heteronuclear multidimensional transferred nuclear overhauser effect analysis of peptide uniformly enriched with 13C and 15N.
Biochemistry, 37, 1998
1F3K
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN L-TYPE CALCIUM CHANNEL BLOCKER
Descriptor:OMEGA-CONOTOXIN TXVII
Authors:Kobayashi, K., Sasaki, T., Sato, K., Kohno, T.
Deposit date:2000-06-05
Release date:2000-12-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of omega-conotoxin TxVII, an L-type calcium channel blocker.
Biochemistry, 39, 2000
1HD0
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HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 (HNRNP D0 RBD1), NMR
Descriptor:PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0)
Authors:Nagata, T., Kurihara, Y., Matsuda, G., Saeki, J., Kohno, T., Yanagida, Y., Ishikawa, F., Uesugi, S., Katahira, M.
Deposit date:1999-05-18
Release date:2000-05-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0.
J.Mol.Biol., 287, 1999
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