2D1N

Collagenase-3 (MMP-13) complexed to a hydroxamic acid inhibitor

Summary for 2D1N

• Entry DOI: 10.2210/pdb2d1n/pdb
• Related: 2D1O
• Descriptor: Collagenase 3, ZINC ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hydorolase metalloprotease, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 38887.93

Authors

Kohno, T.,Hochigai, H.,Yamashita, E.,Tsukihara, T.,Kanaoka, M. (deposition date: 2005-08-29, release date: 2006-06-27, Last modification date: 2023-10-25)

• Primary citation: Kohno, T.,Hochigai, H.,Yamashita, E.,Tsukihara, T.,Kanaoka, M.; Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453; Biochem.Biophys.Res.Commun., 344:315-322, 2006; PubMed: 16603129; DOI: 10.1016/j.bbrc.2006.03.098

Experimental method

X-RAY DIFFRACTION (2.37 Å)