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2D1O

Stromelysin-1 (MMP-3) complexed to a hydroxamic acid inhibitor

Summary for 2D1O
Entry DOI10.2210/pdb2d1o/pdb
Related2D1N
DescriptorStromelysin-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywordshydorolase metalloprotease, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space, extracellular matrix (Probable): P08254
Total number of polymer chains2
Total formula weight39799.99
Authors
Kohno, T.,Hochigai, H.,Yamashita, E.,Tsukihara, T.,Kanaoka, M. (deposition date: 2005-08-30, release date: 2006-06-27, Last modification date: 2023-10-25)
Primary citationKohno, T.,Hochigai, H.,Yamashita, E.,Tsukihara, T.,Kanaoka, M.
Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453
Biochem.Biophys.Res.Commun., 344:315-322, 2006
Cited by
PubMed: 16603129
DOI: 10.1016/j.bbrc.2006.03.098
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.02 Å)
Structure validation

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