Author results

6NUR
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SARS-CORONAVIRUS NSP12 BOUND TO NSP7 AND NSP8 CO-FACTORS
Descriptor:NSP12, NSP8, NSP7, ...
Authors:Kirchdoerfer, R.N., Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-29
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NUS
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SARS-CORONAVIRUS NSP12 BOUND TO NSP8 CO-FACTOR
Descriptor:NSP12, NSP8, ZINC ION
Authors:Kirchdoerfer, R.N., Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-29
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NUT
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EBOLA VIRUS NUCLEOPROTEIN - RNA COMPLEX
Descriptor:Nucleoprotein, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
Authors:Kirchdoerfer, R.N., Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-01
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex
Acta Crystallogr.,Sect.F, 75, 2019
6CRV
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, SINGLE UPWARDS S1 CTD CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRX
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, TWO S1 CTDS IN THE UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRZ
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS0
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, ONE S1 CTD IN AN UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS1
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, TWO S1 CTDS IN AN UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS2
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SARS SPIKE GLYCOPROTEIN - HUMAN ACE2 COMPLEX, STABILIZED VARIANT, ALL ACE2-BOUND PARTICLES
Descriptor:Spike glycoprotein,Fibritin, Angiotensin-converting enzyme 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6BP2
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THERAPEUTIC HUMAN MONOCLONAL ANTIBODY MR191 BOUND TO A MARBURGVIRUS GLYCOPROTEIN
Descriptor:Envelope glycoprotein, Envelope glycoprotein GP2, MR191 Fab Heavy Chain, ...
Authors:King, L.B., Fusco, M.L., Flyak, A.I., Ilinykh, P.A., Huang, K., Gunn, B., Kirchdoerfer, R.N., Hastie, K.M., Sangha, A.K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J.E.J., Saphire, E.O.
Deposit date:2017-11-21
Release date:2018-01-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.172 Å)
Cite:The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Cell Host Microbe, 23, 2018
5VYH
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CRYSTAL STRUCTURE OF MERS-COV S1 N-TERMINAL DOMAIN
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE, FOLIC ACID, ...
Authors:Wang, N., Wrapp, D., Pallesen, J., Ward, A.B., McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VZR
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CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G4 FAB
Descriptor:G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N., Wrapp, D., McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9H
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9I
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9J
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9K
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9L
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9M
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9N
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9O
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9P
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TOH
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CRYSTAL STRUCTURE OF THE MARBURG VIRUS VP35 OLIGOMERIZATION DOMAIN I2
Descriptor:Polymerase cofactor VP35
Authors:Bruhn, J.F., Kirchdoerfer, R.N., Tickle, I.J., Bricogne, G., Saphire, E.O.
Deposit date:2016-10-17
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Structure of the Marburg Virus VP35 Oligomerization Domain.
J. Virol., 91, 2017
5TOI
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CRYSTAL STRUCTURE OF THE MARBURG VIRUS VP35 OLIGOMERIZATION DOMAIN P4222
Descriptor:Polymerase cofactor VP35
Authors:Bruhn, J.F., Tickle, I.J., Bricogne, G., Saphire, E.O.
Deposit date:2016-10-17
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure of the Marburg Virus VP35 Oligomerization Domain.
J. Virol., 91, 2017
5T3T
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EBOLA VIRUS VP30 CTD BOUND TO NUCLEOPROTEIN
Descriptor:Fusion protein of Nucleoprotein and Minor nucleoprotein VP30, SULFATE ION
Authors:Kirchdoerfer, R.N., Moyer, C.L., Abelson, D.M., Saphire, E.O.
Deposit date:2016-08-26
Release date:2016-09-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
Plos Pathog., 12, 2016
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