Author results

2MRA
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR459
Descriptor:De novo designed protein OR459
Authors:Pulavarti, S.V.S.R.K., Kipnis, Y., Sukumaran, D., Maglaqui, M., Janjua, H., Mao, L., Xiao, R., Kornhaber, G., Baker, D., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-07-02
Release date:2014-09-17
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR459
To be Published
3TC6
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR63.
Descriptor:Indole-3-glycerol phosphate synthase, PHOSPHATE ION, DI(HYDROXYETHYL)ETHER
Authors:Vorobiev, S., Su, M., Bjelic, S., Kipnis, Y., Wang, L., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-08-08
Release date:2011-08-24
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
J.Mol.Biol., 426, 2014
3TC7
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR62.
Descriptor:Indole-3-glycerol phosphate synthase, PHOSPHATE ION, ACETIC ACID
Authors:Vorobiev, S., Su, M., Bjelic, S., Kipnis, Y., Wang, L., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-08-08
Release date:2011-08-24
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
J.Mol.Biol., 426, 2014
4LNY
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR422
Descriptor:Engineered Protein OR422, CADMIUM ION, CHLORIDE ION
Authors:Vorobiev, S., Su, M., Bjelic, S., Kipnis, Y., Wang, L., Sahdev, S., Xiao, R., Maglaqui, M., Kogan, S., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-07-12
Release date:2013-08-07
Method:X-RAY DIFFRACTION (1.929 Å)
Cite:Crystal Structure of Engineered Protein OR422.
To be Published
4LT9
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR404
Descriptor:Engineered Protein OR404
Authors:Vorobiev, S., Su, M., Bjelic, S., Kipnis, Y., Wang, L., Sahdev, S., Xiao, R., Kogan, S., Maglaqui, M., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-07-23
Release date:2013-08-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Engineered Protein OR404.
To be Published
3T1G
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ENGINEERING OF ORGANOPHOSPHATE HYDROLASE BY COMPUTATIONAL DESIGN AND DIRECTED EVOLUTION
Descriptor:organophosphate hydrolase, ZINC ION, CALCIUM ION
Authors:Takeuchi, R., Stoddard, B.L.
Deposit date:2011-07-21
Release date:2012-02-08
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.
Nat.Chem.Biol., 8, 2012
4OU1
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CRYSTAL STRUCTURE OF A COMPUTATIONALLY DESIGNED RETRO-ALDOLASE COVALENTLY BOUND TO FOLDING PROBE 1 [(6-METHOXYNAPHTHALEN-2-YL)(OXIRAN-2-YL)METHANOL]
Descriptor:Retro-aldolase, design RA114, (1S,2S)-1-(6-methoxynaphthalen-2-yl)propane-1,2-diol, ...
Authors:Bhabha, G., Zhang, X., Ekiert, D.C.
Deposit date:2014-02-14
Release date:2014-03-05
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PEJ
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CRYSTAL STRUCTURE OF A COMPUTATIONALLY DESIGNED RETRO-ALDOLASE, RA110.4 (CYS FREE)
Descriptor:Retro-aldolase
Authors:Bhabha, G., Zhang, X., Liu, Y., Ekiert, D.C.
Deposit date:2014-04-23
Release date:2015-04-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
4PEK
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CRYSTAL STRUCTURE OF A COMPUTATIONALLY DESIGNED RETRO-ALDOLASE, RA114.3
Descriptor:Retro-aldolase
Authors:Bhabha, G., Zhang, X., Liu, Y., Ekiert, D.C.
Deposit date:2014-04-23
Release date:2015-04-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014