Author results

1JEZ
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THE STRUCTURE OF XYLOSE REDUCTASE, A DIMERIC ALDO-KETO REDUCTASE FROM CANDIDA TENUIS
分子名称:XYLOSE REDUCTASE
著者Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
登録日2001-06-19
公開日2002-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis.
Biochemistry, 41, 2002
1K8C
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CRYSTAL STRUCTURE OF DIMERIC XYLOSE REDUCTASE IN COMPLEX WITH NADP(H)
分子名称:xylose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
登録日2001-10-23
公開日2002-07-05
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis.
Biochemistry, 41, 2002
1LJ8
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CRYSTAL STRUCTURE OF MANNITOL DEHYDROGENASE IN COMPLEX WITH NAD
分子名称:mannitol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
登録日2002-04-19
公開日2002-11-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase binary and ternary complexes. Specificity and catalytic mechanism
J.Biol.Chem., 277, 2002
1M2W
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PSEUDOMONAS FLUORESCENS MANNITOL 2-DEHYDROGENASE TERNARY COMPLEX WITH NAD AND D-MANNITOL
分子名称:mannitol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, D-MANNITOL
著者Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
登録日2002-06-25
公開日2002-11-15
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Pseudomonas fluorescens Mannitol 2-Dehydrogenase Binary and Ternary Complexes. Specificity and Catalytic Mechanism
J.Biol.Chem., 277, 2002
1MI3
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1.8 ANGSTROM STRUCTURE OF XYLOSE REDUCTASE FROM CANDIDA TENUIS IN COMPLEX WITH NAD
分子名称:xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Klimacek, M., Nidetzky, B., Wilson, D.K.
登録日2002-08-21
公開日2003-08-05
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases
Biochem.J., 373, 2003
1PZE
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T.GONDII LDH1 APO FORM
分子名称:lactate dehydrogenase
著者Kavanagh, K.L., Elling, R.A., Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZF
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T.GONDII LDH1 TERNARY COMPLEX WITH APAD+ AND OXALATE
分子名称:lactate dehydrogenase, OXALATE ION, 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE
著者Kavanagh, K.L., Elling, R.A., Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZG
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T.GONDII LDH1 COMPLEXED WITH APAD AND SULFATE AT 1.6 ANGSTROMS
分子名称:lactate dehydrogenase, SULFATE ION, 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE
著者Kavanagh, K.L., Elling, R.A., Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZH
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T.GONDII LDH1 TERNARY COMPLEX WITH NAD AND OXALATE
分子名称:lactate dehydrogenase, OXALATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Elling, R.A., Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1SOV
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TOXOPLASMA GONDII BRADYZOITE-SPECIFIC LDH (LDH2) APO FORM
分子名称:L-lactate dehydrogenase
著者Kavanagh, K.L., Wilson, D.K.
登録日2004-03-15
公開日2005-03-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of apo and ternary forms of Toxoplasma gondii LDH2
To be Published
1SOW
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T. GONDII BRADYZOITE-SPECIFIC LDH (LDH2) IN COMPLEX WITH NAD AND OXALATE
分子名称:L-lactate dehydrogenase, OXALATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Wilson, D.K.
登録日2004-03-15
公開日2005-03-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of apo and ternary forms of Toxoplasma gondii LDH2
To be Published
1YQ7
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HUMAN FARNESYL DIPHOSPHATE SYNTHASE COMPLEXED WITH RISEDRONATE
分子名称:Farnesyl pyrophosphate synthetase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kavanagh, K.L., Guo, K., Von delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-02-01
公開日2005-02-22
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Human farnesyl diphosphate complexed with clinical inhibitor risedronate
To be Published
1YV5
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HUMAN FARNESYL DIPHOSPHATE SYNTHASE COMPLEXED WITH MG AND RISEDRONATE
分子名称:Farnesyl pyrophosphate synthetase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kavanagh, K.L., Guo, K., Von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-02-15
公開日2005-03-01
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
1ZW5
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X-RAY STRUCTURE OF FARNESYL DIPHOSPHATE SYNTHASE PROTEIN
分子名称:farnesyl diphosphate synthase, MAGNESIUM ION, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ...
著者Kavanagh, K.L., Guo, K., Wu, X., von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-06-03
公開日2005-06-28
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2F8A
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CRYSTAL STRUCTURE OF THE SELENOCYSTEINE TO GLYCINE MUTANT OF HUMAN GLUTATHIONE PEROXIDASE 1
分子名称:Glutathione peroxidase 1, MALONIC ACID
著者Kavanagh, K.L., Johansson, C., Smee, C., Gileadi, O., von Delft, F., Weigelt, J., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-12-02
公開日2005-12-13
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
To be Published
2I3Y
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE PEROXIDASE 5
分子名称:Epididymal secretory glutathione peroxidase, 1,2-ETHANEDIOL
著者Kavanagh, K.L., Johansson, C., Rojkova, A., Umeano, C., Bunkoczi, G., Gileadi, O., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-08-21
公開日2006-09-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human glutathione peroxidase 5
To be published
2I9P
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CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE COMPLEXED WITH NAD+
分子名称:3-hydroxyisobutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Papagrigoriou, E., Salah, E., Lukacik, P., Smee, C., Burgess, N., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-09-06
公開日2006-09-26
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
To be Published
2O23
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THE STRUCTURE OF WILD-TYPE HUMAN HADH2 (17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 10) BOUND TO NAD+ AT 1.2 A
分子名称:HADH2 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL
著者Kavanagh, K.L., Shafqat, N., Scholer, K., Debreczeni, J., Zschocke, J., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-11-29
公開日2006-12-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A
To be Published
2P31
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE PEROXIDASE 7
分子名称:Glutathione peroxidase 7, CHLORIDE ION
著者Kavanagh, K.L., Johansson, C., Papagrigoriou, E., Kochan, G., Umeano, C., Gileadi, O., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-03-08
公開日2007-03-20
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human glutathione peroxidase 7
To be Published
2Q80
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CRYSTAL STRUCTURE OF HUMAN GERANYLGERANYL PYROPHOSPHATE SYNTHASE BOUND TO GGPP
分子名称:Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, GERANYLGERANYL DIPHOSPHATE
著者Kavanagh, K.L., Dunford, J.E., Bunkoczi, G., Smee, C., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-06-08
公開日2007-06-19
最終更新日2012-12-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding
J.Biol.Chem., 281, 2006
2QIS
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CRYSTAL STRUCTURE OF HUMAN FARNESYL PYROPHOSPHATE SYNTHASE T210S MUTANT BOUND TO RISEDRONATE
分子名称:Farnesyl pyrophosphate synthetase, MAGNESIUM ION, 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID
著者Kavanagh, K.L., Dunford, J.E., Hozjan, V., Evdokimov, A., Gileadi, O., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-07-05
公開日2007-07-24
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human farnesyl pyrophosphate synthase T210S mutant bound to risedronate.
To be Published
3COS
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CRYSTAL STRUCTURE OF HUMAN CLASS II ALCOHOL DEHYDROGENASE (ADH4) IN COMPLEX WITH NAD AND ZN
分子名称:Alcohol dehydrogenase 4, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Kavanagh, K.L., Shafqat, N., Yue, W., von Delft, F., Bishop, S., Roos, A., Murray, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-03-29
公開日2008-04-15
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human class II alcohol dehydrogenase (ADH4) in complex with NAD and Zn.
To be Published
3CYN
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THE STRUCTURE OF HUMAN GPX8
分子名称:Probable glutathione peroxidase 8, SULFATE ION, GLYCEROL
著者Kavanagh, K.L., Johansson, C., Yue, W.W., Kochan, G., Pike, A.C.W., Murray, J., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Wikstrom, M., Edwards, A.M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-04-25
公開日2008-08-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of human GPX8
To be Published
3DLX
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CRYSTAL STRUCTURE OF HUMAN 3-OXOACID COA TRANSFERASE 1
分子名称:Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, GLYCEROL
著者Kavanagh, K.L., Shafqat, N., Yue, W.W., Picaud, S., Murray, J.W., Maclean, E.M., von Delft, F., Roos, A.K., Arrowsmith, C.H., Wikstrom, M., Edwards, A.M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-06-30
公開日2008-08-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human 3-oxoacid CoA transferase 1.
To be Published
3E04
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CRYSTAL STRUCTURE OF HUMAN FUMARATE HYDRATASE
分子名称:Fumarate hydratase, 1,2-ETHANEDIOL
著者Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-07-30
公開日2008-08-12
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human fumarate hydratase
TO BE PUBLISHED