Author results

5XVB
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[NIFE]-HYDROGENASE (HYB-TYPE) FROM CITROBACTER SP. S-77 IN AN H2-REDUCED CONDITION
Descriptor:[NiFe]-hydrogenase 2 large subunit, [NiFe]-hydrogenase 2 small subunit, MAGNESIUM ION, ...
Authors:Nishikawa, K., Matsuura, H., Muhd Noor, N.D., Tai, H., Hirota, S., Kim, J., Kang, J., Tateno, M., Yoon, K.S., Ogo, S., Shomura, Y., Higuchi, Y.
Deposit date:2017-06-27
Release date:2018-06-27
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Redox-dependent conformational changes of a proximal [4Fe-4S] cluster in Hyb-type [NiFe]-hydrogenase to protect the active site from O2.
Chem.Commun.(Camb.), 54, 2018
5XVC
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[NIFE]-HYDROGENASE (HYB-TYPE) FROM CITROBACTER SP. S-77 IN A FERRICYANIDE-OXIDIZED CONDITION
Descriptor:[NiFe]-hydrogenase 2 large subunit, [NiFe]-hydrogenase 2 small subunit, MAGNESIUM ION, ...
Authors:Nishikawa, K., Matsuura, H., Muhd Noor, N.D., Tai, H., Hirota, S., Kim, J., Kang, J., Tateno, M., Yoon, K.S., Ogo, S., Shomura, Y., Higuchi, Y.
Deposit date:2017-06-27
Release date:2018-06-27
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Redox-dependent conformational changes of a proximal [4Fe-4S] cluster in Hyb-type [NiFe]-hydrogenase to protect the active site from O2.
Chem.Commun.(Camb.), 54, 2018
5XVD
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[NIFE]-HYDROGENASE (HYB-TYPE) FROM CITROBACTER SP. S-77 IN AN AIR-OXIDIZED CONDITION
Descriptor:[NiFe]-hydrogenase 2 large subunit, Hydrogenase-2 small chain, MAGNESIUM ION, ...
Authors:Nishikawa, K., Matsuura, H., Muhd Noor, N.D., Tai, H., Hirota, S., Kim, J., Kang, J., Tateno, M., Yoon, K.S., Ogo, S., Shomura, Y., Higuchi, Y.
Deposit date:2017-06-27
Release date:2018-06-27
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Redox-dependent conformational changes of a proximal [4Fe-4S] cluster in Hyb-type [NiFe]-hydrogenase to protect the active site from O2.
Chem.Commun.(Camb.), 54, 2018
5CJ9
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BACILLUS HALODURANS ARGININE REPRESSOR, ARGR
Descriptor:Arginine repressor, S-1,2-PROPANEDIOL
Authors:Park, Y.W., Kang, J., Yeo, H.Y., Lee, J.Y.
Deposit date:2015-07-14
Release date:2016-06-29
Method:X-RAY DIFFRACTION (2.409 Å)
Cite:Structural Analysis and Insights into the Oligomeric State of an Arginine-Dependent Transcriptional Regulator from Bacillus halodurans.
Plos One, 11, 2016
3Q6S
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THE CRYSTAL STRUCTURE OF THE HETEROCHROMATIN PROTEIN 1 BETA CHROMOSHADOW DOMAIN COMPLEXED WITH A PEPTIDE FROM SHUGOSHIN 1
Descriptor:Chromobox protein homolog 1, Shugoshin-like 1
Authors:Brautigam, C.A., Chaudhary, J., Yu, H.
Deposit date:2011-01-03
Release date:2011-12-14
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
Mol Biol Cell, 22, 2011
4R8Q
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STRUCTURE AND SUBSTRATE RECRUITMENT OF THE HUMAN SPINDLE CHECKPOINT KINASE BUB1
Descriptor:Mitotic checkpoint serine/threonine-protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Tomchick, D.R., Yu, H.
Deposit date:2014-09-02
Release date:2014-11-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.
Mol.Cell, 32, 2008
5KN1
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RECOMBINANT BOVINE SKELETAL CALSEQUESTRIN, HIGH-CA2+ FORM
Descriptor:Calsequestrin, CALCIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Lewis, K.M., Byrd, S., Kang, C.
Deposit date:2016-06-27
Release date:2016-10-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.137 Å)
Cite:Characterization of Post-Translational Modifications to Calsequestrins of Cardiac and Skeletal Muscle.
Int J Mol Sci, 17, 2016
5KN0
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NATIVE BOVINE SKELETAL CALSEQUESTRIN, LOW-CA2+ FORM
Descriptor:Calsequestrin, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Lewis, K.M., Byrd, S., Kang, C.
Deposit date:2016-06-27
Release date:2016-10-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.729 Å)
Cite:Characterization of Post-Translational Modifications to Calsequestrins of Cardiac and Skeletal Muscle.
Int J Mol Sci, 17, 2016
5KN2
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NATIVE BOVINE SKELETAL CALSEQUESTRIN, HIGH-CA2+ FORM
Descriptor:Calsequestrin, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Lewis, K.M., Byrd, S.S., Kang, C.
Deposit date:2016-06-27
Release date:2016-10-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Characterization of Post-Translational Modifications to Calsequestrins of Cardiac and Skeletal Muscle.
Int J Mol Sci, 17, 2016
5KN3
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RECOMBINANT BOVINE SKELETAL CALSEQUESTRIN, LOW-CA2+ FORM
Descriptor:Calsequestrin, CALCIUM ION, (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Lewis, K.M., Byrd, S., Kang, C.
Deposit date:2016-06-27
Release date:2016-10-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Characterization of Post-Translational Modifications to Calsequestrins of Cardiac and Skeletal Muscle.
Int J Mol Sci, 17, 2016
6J10
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CICLOPIROX INHIBITS HEPATITIS B VIRUS SECRETION BY BLOCKING CAPSID ASSEMBLY
Descriptor:Capsid protein, 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one
Authors:Park, S., Jin, M.S., Cho, Y., Kang, J., Kim, S., Park, M., Park, H., Kim, J., Park, S., Hwang, J., Kim, Y., Kim, Y.J.
Deposit date:2018-12-27
Release date:2019-04-17
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Nat Commun, 10, 2019
6DXG
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AMIDOBENZIMIDAZOLE (ABZI) STING AGONISTS
Descriptor:Stimulator of interferon protein, CALCIUM ION, 2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1-[(2R)-2-hydroxy-2-phenylethyl]-1H-benzimidazole-5-carboxamide
Authors:Concha, N.O.
Deposit date:2018-06-28
Release date:2018-11-07
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (1.905 Å)
Cite:Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature, 564, 2018
6DXL
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LINKED AMIDOBENZIMIDAZOLE STING AGONIST
Descriptor:Stimulator of interferon protein, 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}, CALCIUM ION
Authors:Concha, N.O.
Deposit date:2018-06-29
Release date:2018-11-07
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature, 564, 2018
5IY5
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ELECTRON TRANSFER COMPLEX OF CYTOCHROME C AND CYTOCHROME C OXIDASE AT 2.0 ANGSTROM RESOLUTION
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, S., Baba, J., Aoe, S., Shimada, A., Yamashita, E., Tsukihara, T.
Deposit date:2016-03-24
Release date:2017-01-11
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Complex structure of cytochrome c-cytochrome c oxidase reveals a novel protein-protein interaction mode
EMBO J., 36, 2017
5TX5
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RIP1 KINASE ( FLAG 1-294, C34A, C127A, C233A, C240A) WITH GSK772
Descriptor:Receptor-interacting serine/threonine-protein kinase 1, 3-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-5-carboxamide
Authors:Campobasso, N., Ward, P., Thrope, J.
Deposit date:2016-11-15
Release date:2017-07-05
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
J. Med. Chem., 60, 2017
6J53
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CRYSTAL STRUCTURE OF HUMAN HINT1 COMPLEXING WITH ATP
Descriptor:Histidine triad nucleotide-binding protein 1, ADENOSINE MONOPHOSPHATE
Authors:Wang, J., Fang, P., Guo, M.
Deposit date:2019-01-10
Release date:2019-09-25
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Second Messenger Ap4A Propagates Allergic Response by Polymerizing Target Protein HINT1
To Be Published
6J58
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CRYSTAL STRUCTURE OF HUMAN HINT1 COMPLEXING WITH AP4A
Descriptor:Histidine triad nucleotide-binding protein 1, ADENOSINE MONOPHOSPHATE
Authors:Wang, J., Fang, P., Guo, M.
Deposit date:2019-01-10
Release date:2019-09-25
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Second Messenger Ap4A Propagates Allergic Response by Polymerizing Target Protein HINT1
To Be Published
6J5S
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CRYSTAL STRUCTURE OF HUMAN HINT1 MUTANT COMPLEXING WITH AP5A
Descriptor:Histidine triad nucleotide-binding protein 1, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ETHANESULFONIC ACID
Authors:Wang, J., Fang, P., Guo, M.
Deposit date:2019-01-11
Release date:2019-09-25
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Second Messenger Ap4A Propagates Allergic Response by Polymerizing Target Protein HINT1
To Be Published
6J5Z
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CRYSTAL STRUCTURE OF HUMAN HINT1 MUTANT COMPLEXING WITH AP3A
Descriptor:Histidine triad nucleotide-binding protein 1, ETHANESULFONIC ACID, ADENOSINE
Authors:Wang, J., Fang, P., Guo, M.
Deposit date:2019-01-12
Release date:2019-09-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Second Messenger Ap4A Propagates Allergic Response by Polymerizing Target Protein HINT1
To Be Published
6J64
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CRYSTAL STRUCTURE OF HUMAN HINT1 MUTANT COMPLEXING WITH AP4A
Descriptor:Histidine triad nucleotide-binding protein 1, 2-AMINOETHANESULFONIC ACID, BIS(ADENOSINE)-5'-TETRAPHOSPHATE
Authors:Wang, J., Fang, P., Guo, M.
Deposit date:2019-01-14
Release date:2019-09-25
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Second Messenger Ap4A Propagates Allergic Response by Polymerizing Target Protein HINT1
To Be Published
6J65
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CRYSTAL STRUCTURE OF HUMAN HINT1 MUTANT COMPLEXING WITH AP4A II
Descriptor:Histidine triad nucleotide-binding protein 1, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Wang, J., Fang, P., Guo, M.
Deposit date:2019-01-14
Release date:2019-09-25
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Second Messenger Ap4A Propagates Allergic Response by Polymerizing Target Protein HINT1
To Be Published
5AR2
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RIP2 KINASE CATALYTIC DOMAIN (1 - 310)
Descriptor:RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2, CALCIUM ION
Authors:Charnley, A.K., Convery, M.A., Lakdawala Shah, A., Jones, E., Hardwicke, P., Bridges, A., Votta, B.J., Gough, P.J., Marquis, R.W., Bertin, J., Casillas, L.
Deposit date:2015-09-23
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity.
Bioorg.Med.Chem., 23, 2015
5AR3
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RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH AMP-PCP
Descriptor:RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION
Authors:Charnley, A.K., Convery, M.A., Lakdawala Shah, A., Jones, E., Hardwicke, P., Bridges, A., Votta, B.J., Gough, P.J., Marquis, R.W., Bertin, J., Casillas, L.
Deposit date:2015-09-23
Release date:2015-10-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity.
Bioorg.Med.Chem., 23, 2015
5AR4
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RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH SB-203580
Descriptor:RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
Authors:Charnley, A.K., Convery, M.A., Lakdawala Shah, A., Jones, E., Hardwicke, P., Bridges, A., Votta, B.J., Gough, P.J., Marquis, R.W., Bertin, J., Casillas, L.
Deposit date:2015-09-24
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity.
Bioorg.Med.Chem., 23, 2015
5AR5
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RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH BENZIMIDAZOLE
Descriptor:RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2, CALCIUM ION, 2-(2-(4-CHLOROPHENYL)-1H-IMIDAZOL-5-YL)-N,1-BIS(2-METHOXYETHYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE
Authors:Charnley, A.K., Convery, M.A., Lakdawala Shah, A., Jones, E., Hardwicke, P., Bridges, A., Votta, B.J., Gough, P.J., Marquis, R.W., Bertin, J., Casillas, L.
Deposit date:2015-09-24
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity.
Bioorg.Med.Chem., 23, 2015
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