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Structure of a HIF-1a-pVHL-ElonginB-ElonginC Complex
Descriptor:	ELONGIN B, ELONGIN C, Hypoxia-inducible factor 1 alpha, ...
Authors:	Min, J.-H, Yang, H, Ivan, M, Gertler, F, Kaelin JR, W.G, Pavletich, N.P.
Deposit date:	2002-04-30
Release date:	2002-06-12
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling. Science, 296, 2002

Structure of human oligosaccharyltransferase OST-A complex bound to NGI-1
Descriptor:	(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, (2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol, (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium, ...
Authors:	Ramirez, A.S, Kowal, J, Locher, K.P.
Deposit date:	2023-06-30
Release date:	2024-05-08
Method:	ELECTRON MICROSCOPY (3.61 Å)
Cite:	Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-kappa B. Cell, 187, 2024

THE VHL-ELONGINC-ELONGINB STRUCTURE
Descriptor:	PROTEIN (ELONGIN B), PROTEIN (ELONGIN C), PROTEIN (VHL)
Authors:	Stebbins, C.E, Kaelin, W.G, Pavletich, N.P.
Deposit date:	1999-03-13
Release date:	1999-04-21
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function. Science, 284, 1999