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5FU6
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BU of 5fu6 by Molmil
NOT module of the human CCR4-NOT complex (Crystallization mutant)
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
Authors:Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
3RW6
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BU of 3rw6 by Molmil
Structure of nuclear RNA export factor TAP bound to CTE RNA
Descriptor: Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA
Authors:Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E.
Deposit date:2011-05-07
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
3RW7
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BU of 3rw7 by Molmil
Structure of N-terminal domain of nuclear RNA export factor TAP
Descriptor: Nuclear RNA export factor 1
Authors:Teplova, M, Khin, N.W, Wohlbold, L, Izaurralde, E, Patel, D.J.
Deposit date:2011-05-07
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
5J3Q
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BU of 5j3q by Molmil
Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5FU7
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BU of 5fu7 by Molmil
drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ...
Authors:Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
4CZW
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BU of 4czw by Molmil
Structure of the Neurospora crassa Pan2 catalytic unit (protease and nuclease domain)
Descriptor: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ZINC ION
Authors:Christie, M, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-04-22
Release date:2014-06-04
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4CZX
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BU of 4czx by Molmil
Complex of Neurospora crassa PAN2 (WD40) with PAN3 (C-TERM)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ...
Authors:Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-04-22
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4CZV
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BU of 4czv by Molmil
Structure of the Neurospora crassa Pan2 WD40 domain
Descriptor: CHLORIDE ION, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2
Authors:Peter, D, Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-04-22
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4CZY
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BU of 4czy by Molmil
Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ...
Authors:Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-04-22
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
1FO1
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BU of 1fo1 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
Descriptor: NUCLEAR RNA EXPORT FACTOR 1
Authors:Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
Deposit date:2000-08-24
Release date:2000-11-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
1FT8
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BU of 1ft8 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
Descriptor: TIP ASSOCIATING PROTEIN
Authors:Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
Deposit date:2000-09-12
Release date:2000-12-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
2B9Z
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BU of 2b9z by Molmil
Solution structure of FHV B2, a viral suppressor of RNAi
Descriptor: B2 protein
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2005-10-13
Release date:2005-11-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Embo Rep., 6, 2005
4CRW
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BU of 4crw by Molmil
Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G)
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6
Authors:Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-03-01
Release date:2014-05-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
5J3Y
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BU of 5j3y by Molmil
Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex
Descriptor: mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.288 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5J3T
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BU of 5j3t by Molmil
Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, FORMIC ACID, MAGNESIUM ION, ...
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
1T2S
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BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
1YA0
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BU of 1ya0 by Molmil
Crystal structure of the N-terminal domain of human SMG7
Descriptor: SMG-7 transcript variant 2, SULFATE ION
Authors:Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E.
Deposit date:2004-12-17
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
4D0K
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BU of 4d0k by Molmil
Complex of Chaetomium thermophilum PAN2 (WD40-CS1) with PAN3 (C-term)
Descriptor: A-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN
Authors:Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-04-28
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4GMJ
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BU of 4gmj by Molmil
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
Authors:Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
Deposit date:2012-08-16
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
4GML
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BU of 4gml by Molmil
Crystal structure of human NOT1 MIF4G domain
Descriptor: CCR4-NOT transcription complex subunit 1
Authors:Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
Deposit date:2012-08-16
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
2HWX
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BU of 2hwx by Molmil
Structure of human SMG6 E1282C PIN domain mutant.
Descriptor: Telomerase-binding protein EST1A
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006
2HWW
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BU of 2hww by Molmil
Structure of PIN domain of human SMG6
Descriptor: Telomerase-binding protein EST1A
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006
2HWY
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BU of 2hwy by Molmil
Structure of PIN domain of human SMG5.
Descriptor: Protein SMG5
Authors:Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
Deposit date:2006-08-02
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006

 

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