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1II4
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CRYSTAL STRUCTURE OF SER252TRP APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2
Descriptor:HEPARIN-BINDING GROWTH FACTOR 2, FIBROBLAST GROWTH FACTOR RECEPTOR 2
Authors:Ibrahimi, O.A., Eliseenkova, A.V., Plotnikov, A.N., Ornitz, D.M., Mohammadi, M.
Deposit date:2001-04-20
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
1IIL
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CRYSTAL STRUCTURE OF PRO253ARG APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2
Descriptor:HEPARIN-BINDING GROWTH FACTOR 2, FIBROBLAST GROWTH FACTOR RECEPTOR 2
Authors:Ibrahimi, O.A., Eliseenkova, A.V., Plotnikov, A.N., Ornitz, D.M., Mohammadi, M.
Deposit date:2001-04-23
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
1FQ9
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CRYSTAL STRUCTURE OF A TERNARY FGF2-FGFR1-HEPARIN COMPLEX
Descriptor:FIBROBLAST GROWTH FACTOR 2, FIBROBLAST GROWTH FACTOR RECEPTOR 1, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid, ...
Authors:Schlessinger, J., Plotnikov, A.N., Ibrahimi, O.A., Eliseenkova, A.V., Yeh, B.K., Yayon, A., Linhardt, R.J., Mohammadi, M.
Deposit date:2000-09-04
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization.
Mol.Cell, 6, 2000
1IHK
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CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 (FGF9)
Descriptor:GLIA-ACTIVATING FACTOR, PHOSPHATE ION
Authors:Plotnikov, A.N., Eliseenkova, A.V., Ibrahimi, O.A., Lemmon, M.A., Mohammadi, M.
Deposit date:2001-04-19
Release date:2001-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition.
J.Biol.Chem., 276, 2001
1RY7
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CRYSTAL STRUCTURE OF THE 3 IG FORM OF FGFR3C IN COMPLEX WITH FGF1
Descriptor:Heparin-binding growth factor 1, Fibroblast growth factor receptor 3
Authors:Olsen, S.K., Ibrahimi, O.A., Raucci, A., Zhang, F., Eliseenkova, A.V., Yayon, A., Basilico, C., Linhardt, R.J., Schlessinger, J., Mohammadi, M.
Deposit date:2003-12-19
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.
Proc.Natl.Acad.Sci.Usa, 101, 2004
2FDB
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CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR (FGF)8B IN COMPLEX WITH FGF RECEPTOR (FGFR) 2C
Descriptor:fibroblast growth factor 8 isoform B, Fibroblast growth factor receptor 2
Authors:Mohammadi, M., Olsen, S.K.
Deposit date:2005-12-13
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Genes Dev., 20, 2006
2P23
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CRYSTAL STRUCTURE OF HUMAN FGF19
Descriptor:Fibroblast growth factor 19
Authors:Mohammadi, M.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2P39
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CRYSTAL STRUCTURE OF HUMAN FGF23
Descriptor:Fibroblast growth factor 23, SUCROSE OCTASULFATE
Authors:Mohammadi, M.
Deposit date:2007-03-08
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
3OJ2
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CRYSTAL STRUCTURE OF FGF1 COMPLEXED WITH THE ECTODOMAIN OF FGFR2B HARBORING THE A172F PFEIFFER SYNDROME MUTATION
Descriptor:Heparin-binding growth factor 1, Fibroblast growth factor receptor 2, SULFATE ION
Authors:Beenken, A., Mohammadi, M.
Deposit date:2010-08-20
Release date:2011-08-31
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012
3OJM
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CRYSTAL STRUCTURE OF FGF1 COMPLEXED WITH THE ECTODOMAIN OF FGFR2B HARBORING P253R APERT MUTATION
Descriptor:Heparin-binding growth factor 1, Fibroblast growth factor receptor 2, SULFATE ION
Authors:Beenken, A., Mohammadi, M.
Deposit date:2010-08-23
Release date:2011-08-31
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012
3OJV
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CRYSTAL STRUCTURE OF FGF1 COMPLEXED WITH THE ECTODOMAIN OF FGFR1C EXHIBITING AN ORDERED LIGAND SPECIFICITY-DETERMINING BETAC'-BETAE LOOP
Descriptor:Heparin-binding growth factor 1, Basic fibroblast growth factor receptor 1, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid, ...
Authors:Beenken, A., Mohammadi, M.
Deposit date:2010-08-23
Release date:2011-12-28
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012