Author results

1BBJ
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CRYSTAL STRUCTURE OF A CHIMERIC FAB' FRAGMENT OF AN ANTIBODY BINDING TUMOUR CELLS
Descriptor:IGG4-KAPPA B72.3 FAB (LIGHT CHAIN), IGG4-KAPPA B72.3 FAB (HEAVY CHAIN)
Authors:Brady, R.L., Hubbard, R.E., Todd, R.J.
Deposit date:1992-04-30
Release date:1994-01-31
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of a chimeric Fab' fragment of an antibody binding tumour cells.
J.Mol.Biol., 227, 1992
1PMB
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THE DETERMINATION OF THE CRYSTAL STRUCTURE OF RECOMBINANT PIG MYOGLOBIN BY MOLECULAR REPLACEMENT AND ITS REFINEMENT
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Smerdon, S.J., Oldfield, T.J., Dodson, E.J., Dodson, G.G., Hubbard, R.E., Wilkinson, A.J.
Deposit date:1989-11-27
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Determination of the crystal structure of recombinant pig myoglobin by molecular replacement and its refinement.
Acta Crystallogr.,Sect.B, 46, 1990
1PMI
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CANDIDA ALBICANS PHOSPHOMANNOSE ISOMERASE
Descriptor:PHOSPHOMANNOSE ISOMERASE, ZINC ION
Authors:Cleasby, A., Skarzynski, T., Wonacott, A., Davies, G.J., Hubbard, R.E., Proudfoot, A.E.I., Wells, T.N.C., Payton, M.A., Bernard, A.R.
Deposit date:1996-04-03
Release date:1997-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The x-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution.
Nat.Struct.Biol., 3, 1996
1BYG
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KINASE DOMAIN OF HUMAN C-TERMINAL SRC KINASE (CSK) IN COMPLEX WITH INHIBITOR STAUROSPORINE
Descriptor:PROTEIN (C-TERMINAL SRC KINASE), STAUROSPORINE
Authors:Antson, A.A., Lamers, M.B.A.C., Scott, R.K., Williams, D.H., Hubbard, R.E.
Deposit date:1998-10-14
Release date:1999-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine.
J.Mol.Biol., 285, 1999
1DQD
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CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR
Descriptor:FAB HGR-2 F6
Authors:Wright, L.M., Brzozowski, A.M., Hubbard, R.E., Pike, A.C.W., Roberts, S.M., Skovgaard, R.N., Svendsen, I., Vissing, H., Bywater, R.P.
Deposit date:2000-01-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor.
Acta Crystallogr.,Sect.D, 56, 2000
1FJ3
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THERMOLYSIN (50% ACETONE SOAKED)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-07
Release date:2001-04-18
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJO
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THERMOLYSIN (60% ACETONE SOAKED CRYSTALS)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-08
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJQ
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THERMOLYSIN (70% ACETONE SOAKED CRYSTALS)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-08
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJT
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THERMOLYSIN (50% ACETONITRILE SOAKED CRYSTALS)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-08
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJU
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THERMOLYSIN (80% ACETONITRILE SOAKED CRYSTALS)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-08
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJV
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THERMOLYSIN (60% ACETONITRILE SOAKED CRYSTALS)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-08
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1FJW
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THERMOLYSIN (50 MM PHENOL SOAKED)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Groom, C.R., Hubbard, R.E.
Deposit date:2000-08-08
Release date:2001-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
1GLO
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CRYSTAL STRUCTURE OF CYS25SER MUTANT OF HUMAN CATHEPSIN S
Descriptor:CATHEPSIN S
Authors:Turkenburg, J.P., Lamers, M.B.A.C., Brzozowski, A.M., Wright, L.M., Hubbard, R.E., Sturt, S.L., Williams, D.H.
Deposit date:2001-08-31
Release date:2002-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a Cys25->Ser Mutant of Human Cathepsin Cathepsin S
Acta Crystallogr.,Sect.D, 58, 2002
1GZI
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CRYSTAL STRUCTURE OF TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT, AT 1.8 ANGSTROM RESOLUTION
Descriptor:HPLC-12 TYPE III ANTIFREEZE PROTEIN
Authors:Antson, A.A., Lewis, S., Roper, D.I., Smith, D.J., Hubbard, R.E.
Deposit date:1996-10-25
Release date:1997-09-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of Type III Antifreeze Protein from Ocean Pout
To be Published
1HG7
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HIGH RESOLUTION STRUCTURE OF HPLC-12 TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT MACROZOARCES AMERICANUS
Descriptor:HPLC-12 TYPE III ANTIFREEZE PROTEIN, SULFATE ION
Authors:Antson, A.A., Smith, D.J., Roper, D.I., Lewis, S., Caves, L.S.D., Verma, C.S., Buckley, S.L., Lillford, P.J., Hubbard, R.E.
Deposit date:2000-12-13
Release date:2001-01-31
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Understanding the Mechanism of Ice Binding by Type III Antifreeze Protein
J.Mol.Biol., 305, 2001
1TLI
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THERMOLYSIN (2% ISOPROPANOL SOAKED CRYSTALS)
Descriptor:THERMOLYSIN, ZINC ION, CALCIUM ION, ...
Authors:English, A.C., Done, S.H., Groom, C.R., Hubbard, R.E.
Deposit date:1998-10-27
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
1TLX
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THERMOLYSIN (NATIVE)
Descriptor:THERMOLYSIN, VALINE, LYSINE, ...
Authors:English, A.C., Done, S.H., Groom, C.R., Hubbard, R.E.
Deposit date:1998-11-02
Release date:2000-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
1UY6
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HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(3,4,5-TRIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 9-BUTYL-8-(3,4,5-TRIMETHOXYBENZYL)-9H-PURIN-6-AMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UY7
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HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(4-METHOXY-BENZYL)-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 9-BUTYL-8-(4-METHOXYBENZYL)-9H-PURIN-6-AMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UY8
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HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(3-TRIMETHOXY-BENZYL)-9H-PURIN-6YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 9-BUTYL-8-(3-METHOXYBENZYL)-9H-PURIN-6-AMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UY9
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HUMAN HSP90-ALPHA WITH 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UYC
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HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(2,5-DIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 9-BUTYL-8-(2,5-DIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UYD
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HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 9-BUTYL-8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UYE
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HUMAN HSP90-ALPHA WITH 8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1UYF
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HUMAN HSP90-ALPHA WITH 8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-2-FLUORO-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE
Descriptor:HEAT SHOCK PROTEIN HSP 90-ALPHA, 8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-2-FLUORO-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE
Authors:Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P., Hubbard, R.E.
Deposit date:2004-03-02
Release date:2004-07-01
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004