1PN5
| NMR structure of the NALP1 Pyrin domain (PYD) | Descriptor: | NACHT-, LRR- and PYD-containing protein 2 | Authors: | Hiller, S, Kohl, A, Fiorito, F, Herrmann, T, Wider, G, Tschopp, J, Grutter, M.G, Wuthrich, K. | Deposit date: | 2003-06-12 | Release date: | 2003-10-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain Structure, 11, 2003
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2K4T
| Solution structure of human VDAC-1 in LDAO micelles | Descriptor: | Voltage-dependent anion-selective channel protein 1 | Authors: | Hiller, S, Garces, R.G, Malia, T.J, Orekhov, V.Y, Colombini, M, Wagner, G. | Deposit date: | 2008-06-17 | Release date: | 2008-09-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science, 321, 2008
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7R1V
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7R1W
| E. coli BAM complex (BamABCDE) bound to dynobactin A | Descriptor: | Dynobactin A, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Jakob, R.P, Hiller, S, Maier, T. | Deposit date: | 2022-02-03 | Release date: | 2022-09-28 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Computational identification of a systemic antibiotic for gram-negative bacteria. Nat Microbiol, 7, 2022
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7P1C
| Crystal structure of E.coli BamA beta-barrel in complex with darobactin B | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Outer membrane protein assembly factor BamA, TRP-ASN-UX8-THR-LYS-ARG-PHE | Authors: | Jakob, R.P, Modaresi, S.M, Hiller, S, Maier, T. | Deposit date: | 2021-07-01 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutasynthetic Production and Antimicrobial Characterization of Darobactin Analogs. Microbiol Spectr, 9, 2021
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8CPQ
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4YYP
| Crystal structure of human PLK4-PB3 in complex with STIL-CC | Descriptor: | CHLORIDE ION, SCL-interrupting locus protein, Serine/threonine-protein kinase PLK4 | Authors: | Imseng, S, Arquint, C, Gabryjonczyk, A, Boehm, R, Sauer, E, Hiller, S, Nigg, E.A, Maier, T. | Deposit date: | 2015-03-24 | Release date: | 2015-07-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | STIL binding to Polo-box 3 of PLK4 regulates centriole duplication. Elife, 4, 2015
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7AQS
| Crystal structure of E. coli DPS in space group P1 | Descriptor: | DNA protection during starvation protein, FE (III) ION | Authors: | Jakob, R.P, Pipercevic, J, Righetto, R, Goldie, K, Stahlberg, H, Maier, T, Hiller, S. | Deposit date: | 2020-10-22 | Release date: | 2021-09-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Identification of a Dps contamination in Mitomycin-C-induced expression of Colicin Ia. Biochim Biophys Acta Biomembr, 1863, 2021
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8ARV
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6TIQ
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6TIR
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6ZPN
| Crystal structure of Chaetomium thermophilum Raptor | Descriptor: | WD_REPEATS_REGION domain-containing protein | Authors: | Imseng, S, Boehm, R, Jakob, R.P, Hall, M.N, Hiller, S, Maier, T. | Deposit date: | 2020-07-08 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1. Mol.Cell, 81, 2021
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7NRF
| Crystal structure of E.coli BamA beta-barrel in complex with darobactin (crystal form 2) | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Darobactin, MAGNESIUM ION, ... | Authors: | Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S. | Deposit date: | 2021-03-03 | Release date: | 2021-04-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593, 2021
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7NRE
| Crystal structure of E.coli BamA beta-barrel in complex with darobactin (crystal form 1) | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Darobactin, MAGNESIUM ION, ... | Authors: | Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S. | Deposit date: | 2021-03-03 | Release date: | 2021-04-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593, 2021
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7NRI
| Structure of the darobactin-bound E. coli BAM complex (BamABCDE) | Descriptor: | 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S. | Deposit date: | 2021-03-03 | Release date: | 2021-04-21 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593, 2021
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6FSU
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4C00
| Crystal structure of TamA from E. coli | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ACETATE ION, CHLORIDE ION, ... | Authors: | Gruss, F, Zaehringer, F, Jakob, R.P, Burmann, B.M, Hiller, S, Maier, T. | Deposit date: | 2013-07-30 | Release date: | 2013-09-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Structural Basis of Autotransporter Translocation by Tama Nat.Struct.Mol.Biol., 20, 2013
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4BZA
| Crystal structure of TamA POTRA domains 1-3 from E. coli | Descriptor: | 1,2-ETHANEDIOL, TRANSLOCATION AND ASSEMBLY MODULE TAMA | Authors: | Jakob, R.P, Gruss, F, Zaehringer, F, Burmann, B.M, Hiller, S, Maier, T. | Deposit date: | 2013-07-24 | Release date: | 2013-09-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.839 Å) | Cite: | The Structural Basis of Autotransporter Translocation by Tama Nat.Struct.Mol.Biol., 20, 2013
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4QL0
| Crystal Structure Analysis of the Membrane Transporter FhaC (double mutant V169T, I176N) | Descriptor: | DI(HYDROXYETHYL)ETHER, Filamentous hemagglutinin transporter protein FhaC, HEXAETHYLENE GLYCOL, ... | Authors: | Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V. | Deposit date: | 2014-06-10 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conserved Omp85 lid-lock structure and substrate recognition in FhaC Nat Commun, 6, 2015
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4QKY
| Crystal Structure Analysis of the Membrane Transporter FhaC | Descriptor: | Filamentous hemagglutinin transporter protein FhaC, PHOSPHATE ION | Authors: | Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V. | Deposit date: | 2014-06-10 | Release date: | 2014-10-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Conserved Omp85 lid-lock structure and substrate recognition in FhaC Nat Commun, 6, 2015
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5NH1
| Structure of the C-terminal domain of human Gasdermin D | Descriptor: | Gasdermin-D | Authors: | Anton, L, Sborgi, L, Hiller, S, Broz, P, Maier, T. | Deposit date: | 2017-03-21 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Insights into Gasdermin D activation from the crystal structure of its C-terminal domain Biorxiv, 2017
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5OWI
| The dynamic dimer structure of the chaperone Trigger Factor (conformer 1) | Descriptor: | Trigger factor | Authors: | Morgado, L, Burmann, B.M, Sharpe, T, Mazur, A, Hiller, S. | Deposit date: | 2017-09-01 | Release date: | 2017-11-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The dynamic dimer structure of the chaperone Trigger Factor. Nat Commun, 8, 2017
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5OWJ
| The dynamic dimer structure of the chaperone Trigger Factor (conformer 2) | Descriptor: | Trigger factor | Authors: | Morgado, L, Burmann, B.M, Sharpe, T, Mazur, A, Hiller, S. | Deposit date: | 2017-09-01 | Release date: | 2017-11-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The dynamic dimer structure of the chaperone Trigger Factor. Nat Commun, 8, 2017
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2N1F
| Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy | Descriptor: | Apoptosis-associated speck-like protein | Authors: | Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S. | Deposit date: | 2015-04-01 | Release date: | 2015-10-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | Cite: | Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proc.Natl.Acad.Sci.USA, 112, 2015
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6YTC
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