2C1E
| Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors. | Descriptor: | AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ... | Authors: | Grutter, M.G. | Deposit date: | 2005-09-14 | Release date: | 2006-09-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10. J.Med.Chem., 49, 2006
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3MAU
| Crystal structure of StSPL in complex with phosphoethanolamine | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, sphingosine-1-phosphate lyase, ... | Authors: | Bourquin, F, Grutter, M.G, Capitani, G. | Deposit date: | 2010-03-24 | Release date: | 2010-08-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
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1NQ3
| Crystal structure of the mammalian tumor associated antigen UK114 | Descriptor: | 14.3 kDa perchloric acid soluble protein | Authors: | Deriu, D, Briand, C, Mistiniene, E, Naktinis, V, Grutter, M.G. | Deposit date: | 2003-01-21 | Release date: | 2003-08-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and oligomeric state of the mammalian tumour-associated antigen UK114. Acta Crystallogr.,Sect.D, 59, 2003
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2BKK
| Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ... | Authors: | Kohl, A, Amstutz, P, Parizek, P, Binz, H.K, Briand, C, Capitani, G, Forrer, P, Pluckthun, A, Grutter, M.G. | Deposit date: | 2005-02-16 | Release date: | 2005-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein Structure, 13, 2005
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2BKG
| Crystal structure of E3_19 a designed ankyrin repeat protein | Descriptor: | SYNTHETIC CONSTRUCT ANKYRIN REPEAT PROTEIN E3_19 | Authors: | Binz, H.K, Kohl, A, Pluckthun, A, Grutter, M.G. | Deposit date: | 2005-02-16 | Release date: | 2006-06-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of a Consensus-Designed Ankyrin Repeat Protein: Implications for Stability Proteins: Struct., Funct., Bioinf., 65, 2006
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3BFW
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3BFQ
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3BWU
| Crystal structure of the ternary complex of FimD (N-Terminal Domain, FimDN) with FimC and the N-terminally truncated pilus subunit FimF (FimFt) | Descriptor: | 1,2-ETHANEDIOL, Chaperone protein fimC, DI(HYDROXYETHYL)ETHER, ... | Authors: | Eidam, O, Grutter, M.G, Capitani, G. | Deposit date: | 2008-01-10 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD Febs Lett., 582, 2008
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3C7M
| Crystal structure of reduced DsbL | Descriptor: | CADMIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Stirnimann, C.U, Grimshaw, J.P.A, Glockshuber, R, Grutter, M.G, Capitani, G. | Deposit date: | 2008-02-07 | Release date: | 2008-07-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli. J.Mol.Biol., 380, 2008
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3SQB
| Structure of the major type 1 pilus subunit FimA bound to the FimC chaperone | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chaperone protein fimC, ... | Authors: | Scharer, M.A, Eidam, O, Grutter, M.G, Glockshuber, R, Capitani, G. | Deposit date: | 2011-07-05 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Quality control of disulfide bond formation in pilus subunits by the chaperone FimC. Nat.Chem.Biol., 8, 2012
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3THM
| Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ... | Authors: | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | Deposit date: | 2011-08-19 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ., 19, 2012
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3TJE
| Crystal structure of Fas receptor extracellular domain in complex with Fab E09 | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | Authors: | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | Deposit date: | 2011-08-24 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ., 19, 2012
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2CI4
| Crystal Structure of Dimethylarginine dimethylaminohydrolase I crystal form II | Descriptor: | NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2006-03-17 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors. Structure, 14, 2006
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2CI3
| Crystal Structure of Dimethylarginine dimethylaminohydrolase crystal form I | Descriptor: | NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2006-03-17 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors. Structure, 14, 2006
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2CJX
| Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis | Descriptor: | CASPASE-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE | Authors: | Ganesan, R, Mittl, P.R.E, Jelakovic, S, Grutter, M.G. | Deposit date: | 2006-04-09 | Release date: | 2006-06-27 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-Ray Structure Analysis J.Mol.Biol., 359, 2006
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2CI6
| Crystal Structure of Dimethylarginine dimethylaminohydrolase I bound with Zinc low pH | Descriptor: | NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1, ZINC ION | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2006-03-17 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors Structure, 14, 2006
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2CI7
| Crystal structure of Dimethylarginine Dimethylaminohydrolase I in complex with Zinc, high pH | Descriptor: | GLYCINE, NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1, ... | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2006-03-17 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors. Structure, 14, 2006
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2CNO
| Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors. | Descriptor: | Aza-peptide epoxide, Caspase-3 | Authors: | Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G. | Deposit date: | 2006-05-22 | Release date: | 2007-05-22 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors Biochemistry, 45, 2006
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2C6Z
| crystal structure of dimethylarginine dimethylaminohydrolase I in complex with citrulline | Descriptor: | CITRIC ACID, CITRULLINE, NG, ... | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2005-11-16 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors Structure, 14, 2006
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2CNL
| Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors. | Descriptor: | AZA-PEPTIDE EPOXIDE, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17 | Authors: | Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Grutter, M.G, Powers, J.C. | Deposit date: | 2006-05-22 | Release date: | 2007-05-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors Biochemistry, 45, 2006
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2CNK
| Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors. | Descriptor: | AZA-PEPTIDE EXPOXIDE, CASPASE-3 P12 SUBUNIT, CASPASE-3 P17 SUBUNIT | Authors: | Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G. | Deposit date: | 2006-05-22 | Release date: | 2007-05-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors Biochemistry, 45, 2006
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2CI1
| Crystal Structure of dimethylarginine dimethylaminohydrolase I in complex with S-nitroso-Lhomocysteine | Descriptor: | CITRIC ACID, NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2006-03-17 | Release date: | 2006-05-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors. Structure, 14, 2006
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2CI5
| Crystal structure of Dimethylarginine Dimethylaminohydrolase I in complex with L-homocysteine | Descriptor: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, CITRIC ACID, NG, ... | Authors: | Frey, D, Braun, O, Briand, C, Vasak, M, Grutter, M.G. | Deposit date: | 2006-03-17 | Release date: | 2006-05-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors Structure, 14, 2006
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2DKO
| Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis | Descriptor: | Caspase-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE | Authors: | Mittl, P.R.E, Ganesan, R, Jelakovic, S, Grutter, M.G. | Deposit date: | 2006-04-12 | Release date: | 2006-07-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis J.Mol.Biol., 359, 2006
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2CJY
| Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis | Descriptor: | CASPASE-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE | Authors: | Ganesan, R, Mittl, P.R.E, Jelakovic, S, Grutter, M.G. | Deposit date: | 2006-04-09 | Release date: | 2006-06-27 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-Ray Structure Analysis J.Mol.Biol., 359, 2006
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