6NHL
 
 | | Crystal structure of QueE from Escherichia coli | | Descriptor: | 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | | Authors: | Grell, T.A.J, Bell, B.N, Nguyen, C, Dowling, D.P, Drennan, C.L. | | Deposit date: | 2018-12-23 | | Release date: | 2019-01-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Protein Sci., 28, 2019
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6DJT
 | | Structure of TYW1 with a lysine-pyruvate adduct bound | | Descriptor: | DI(HYDROXYETHYL)ETHER, FE2/S3 CLUSTER, GLYCEROL, ... | | Authors: | Grell, T.A.J, Drennan, C.L. | | Deposit date: | 2018-05-26 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.
J. Am. Chem. Soc., 140, 2018
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6EFN
 | | Structure of a RiPP maturase, SkfB | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | Authors: | Grell, T.A.J, Drennan, C.L. | | Deposit date: | 2018-08-16 | | Release date: | 2018-10-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.291 Å) | | Cite: | Structure of a RiPP maturase, SkfB
J.Biol.Chem., 2018
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8EYO
 | | Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 with NADP bound | | Descriptor: | CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, ... | | Authors: | Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X. | | Deposit date: | 2022-10-28 | | Release date: | 2023-02-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
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8EYN
 | | Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 in Apo Form | | Descriptor: | CITRIC ACID, NADP-dependent malic enzyme, mitochondrial | | Authors: | Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X. | | Deposit date: | 2022-10-28 | | Release date: | 2023-02-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
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8E76
 | | Cryo-EM structure of Apo form ME3 | | Descriptor: | NADP-dependent malic enzyme, mitochondrial | | Authors: | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | | Deposit date: | 2022-08-23 | | Release date: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
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8E8O
 | | Cryo-EM structure of human ME3 in the presence of citrate | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, mitochondrial | | Authors: | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | | Deposit date: | 2022-08-25 | | Release date: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
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8E78
 | | Cryo-EM structure of human ME3 in the presence of citrate | | Descriptor: | NADP-dependent malic enzyme, mitochondrial | | Authors: | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | | Deposit date: | 2022-08-23 | | Release date: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer.
Heliyon, 8, 2022
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5TGS
 | | Crystal Structure of QueE from Bacillus subtilis with methionine bound | | Descriptor: | 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... | | Authors: | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | | Deposit date: | 2016-09-28 | | Release date: | 2017-01-18 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.548 Å) | | Cite: | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
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5TH5
 | | Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound | | Descriptor: | 5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | Authors: | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | | Deposit date: | 2016-09-29 | | Release date: | 2017-01-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.407 Å) | | Cite: | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
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