Author results

4V4B
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STRUCTURE OF THE RIBOSOMAL 80S-EEF2-SORDARIN COMPLEX FROM YEAST OBTAINED BY DOCKING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO A 11.7 A CRYO-EM MAP.
Descriptor:18S ribosomal RNA, Elongation factor 2, 40S ribosomal protein S0-A, ...
Authors:Spahn, C.M., Gomez-Lorenzo, M.G., Grassucci, R.A., Jorgensen, R., Andersen, G.R., Beckmann, R., Penczek, P.A., Ballesta, J.P.G., Frank, J.
Deposit date:2004-01-06
Release date:2014-07-09
Last modified:2015-03-18
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
4V69
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TERNARY COMPLEX-BOUND E.COLI 70S RIBOSOME.
Descriptor:30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Villa, E., Sengupta, J., Trabuco, L.G., LeBarron, J., Baxter, W.T., Shaikh, T.R., Grassucci, R.A., Nissen, P., Ehrenberg, M., Schulten, K., Frank, J.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009
1EG0
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FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME
Descriptor:FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, HELIX 95 OF 23S RRNA, ...
Authors:Gabashvili, I.S., Agrawal, R.K., Spahn, C.M.T., Grassucci, R.A., Svergun, D.I., Frank, J., Penczek, P.
Deposit date:2000-02-11
Release date:2000-03-06
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Solution structure of the E. coli 70S ribosome at 11.5 A resolution.
Cell(Cambridge,Mass.), 100, 2000
1FCW
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TRNA POSITIONS DURING THE ELONGATION CYCLE
Descriptor:TRNAPHE
Authors:Agrawal, R.K., Spahn, C.M.T., Penczek, P., Grassucci, R.A., Nierhaus, K.H., Frank, J.
Deposit date:2000-07-19
Release date:2000-08-11
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle.
J.Cell Biol., 150, 2000
1LS2
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FITTING OF EF-TU AND TRNA IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:Phenylalanine transfer RNA, Elongation Factor Tu
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1LU3
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SEPARATE FITTING OF THE ANTICODON LOOP REGION OF TRNA (NUCLEOTIDE 26-42) IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:PHENYLALANINE TRANSFER RNA
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-21
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1MI6
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DOCKING OF THE MODIFIED RF2 X-RAY STRUCTURE INTO THE LOW RESOLUTION CRYO-EM MAP OF RF2 E.COLI 70S RIBOSOME
Descriptor:peptide chain release factor RF-2
Authors:Rawat, U.B.S., Zavialov, A.V., Sengupta, J., Valle, M., Grassucci, R.A., Linde, J., Vestergaard, B., Ehrenberg, M., Frank, J.
Deposit date:2002-08-22
Release date:2003-01-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:A cryo-electron microscopic study of ribosome-bound termination factor RF2
Nature, 421, 2003
1MVR
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DECODING CENTER & PEPTIDYL TRANSFERASE CENTER FROM THE X-RAY STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME, ALIGNED TO THE LOW RESOLUTION CRYO-EM MAP OF E.COLI 70S RIBOSOME
Descriptor:mRNA, triplet codon (A-site), Helix 34 of 16S rRNA, ...
Authors:Rawat, U.B., Zavialov, A.V., Sengupta, J., Valle, M., Grassucci, R.A., Linde, J., Vestergaard, B., Ehrenberg, M., Frank, J.
Deposit date:2002-09-26
Release date:2003-04-01
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (12.8 Å)
Cite:A cryo-electron microscopic study of ribosome-bound termination factor RF2
Nature, 421, 2003
1RY1
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STRUCTURE OF THE SIGNAL RECOGNITION PARTICLE INTERACTING WITH THE ELONGATION-ARRESTED RIBOSOME
Descriptor:SRP Alu domain, SRP S domain, SRP RNA, ...
Authors:Halic, M., Becker, T., Pool, M.R., Spahn, C.M., Grassucci, R.A., Frank, J., Beckmann, R.
Deposit date:2003-12-19
Release date:2004-04-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Structure of the signal recognition particle interacting with the elongation-arrested ribosome
Nature, 427, 2004
1T1M
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BINDING POSITION OF RIBOSOME RECYCLING FACTOR (RRF) ON THE E. COLI 70S RIBOSOME
Descriptor:dodecamer fragment of double helix from 23S rRNA, 42-mer fragment of double helix from 16S rRNA, ribosome recycling factor
Authors:Agrawal, R.K., Sharma, M.R., Kiel, M.C., Hirokawa, G., Booth, T.M., Spahn, C.M., Grassucci, R.A., Kaji, A., Frank, J.
Deposit date:2004-04-16
Release date:2004-06-15
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
Proc.Natl.Acad.Sci.USA, 101, 2004
1T1O
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COMPONENTS OF THE CONTROL 70S RIBOSOME TO PROVIDE REFERENCE FOR THE RRF BINDING SITE
Descriptor:dodecamer fragment of double helix from 23S rRNA, 19-mer fragment of the 23S rRNA, 42-mer fragment of double helix from 16S rRNA
Authors:Agrawal, R.K., Sharma, M.R., Kiel, M.C., Hirokawa, G., Booth, T.M., Spahn, C.M., Grassucci, R.A., Kaji, A., Frank, J.
Deposit date:2004-04-16
Release date:2004-06-15
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
Proc.Natl.Acad.Sci.USA, 101, 2004
3J5Y
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STRUCTURE OF THE MAMMALIAN RIBOSOMAL PRE-TERMINATION COMPLEX ASSOCIATED WITH ERF1-ERF3-GDPNP
Descriptor:Eukaryotic peptide chain release factor subunit 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', ...
Authors:des Georges, A., Hashem, Y., Unbehaun, A., Grassucci, R.A., Taylor, D., Hellen, C.U.T., Pestova, T.V., Frank, J.
Deposit date:2013-11-21
Release date:2013-12-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
4C4Q
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CRYO-EM MAP OF THE CSFV IRES IN COMPLEX WITH THE SMALL RIBOSOMAL 40S SUBUNIT AND DHX29
Descriptor:INTERNAL RIBOSOMAL ENTRY SITE
Authors:Hashem, Y., desGeorges, A., Dhote, V., Langlois, R., Liao, H.Y., Grassucci, R.A., Pestova, T.V., Hellen, C.U.T., Frank, J.
Deposit date:2013-09-07
Release date:2013-10-30
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Hepatitis-C-Virus-Like Internal Ribosome Entry Sites Displace Eif3 to Gain Access to the 40S Subunit
Nature, 503, 2013
4V8M
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HIGH-RESOLUTION CRYO-ELECTRON MICROSCOPY STRUCTURE OF THE TRYPANOSOMA BRUCEI RIBOSOME
Descriptor:40S RIBOSOMAL PROTEIN S3A, PUTATIVE, 40S RIBOSOMAL PROTEIN S4, ...
Authors:Hashem, Y., des Georges, A., Fu, J., Buss, S.N., Jossinet, F., Jobe, A., Zhang, Q., Liao, H.Y., Grassucci, R.A., Bajaj, C., Westhof, E., Madison-Antenucci, S., Frank, J.
Deposit date:2012-12-09
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (5.57 Å)
Cite:High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Nature, 494, 2013
5KBS
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CRYO-EM STRUCTURE OF GLUA2-0XSTZ AT 8.7 ANGSTROM RESOLUTION
Descriptor:Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2016-06-03
Release date:2016-07-13
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
5KBT
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CRYO-EM STRUCTURE OF GLUA2-1XSTZ COMPLEX AT 6.4 ANGSTROM RESOLUTION
Descriptor:Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2016-06-03
Release date:2016-07-13
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
5KBU
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CRYO-EM STRUCTURE OF GLUA2-2XSTZ COMPLEX AT 7.8 ANGSTROM RESOLUTION
Descriptor:Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2016-06-03
Release date:2016-07-13
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
5T5H
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STRUCTURE AND ASSEMBLY MODEL FOR THE TRYPANOSOMA CRUZI 60S RIBOSOMAL SUBUNIT
Descriptor:RNA LARGE SUBUNIT ALPHA, RNA LARGE SUBUNIT BETA, 5.8S rRNA, ...
Authors:Liu, Z., Gutierrez-Vargas, C., Wei, J., Grassucci, R.A., Ramesh, M., Espina, N., Sun, M., Tutuncuoglu, B., Madison-Antenucci, S., Woolford Jr., J.L., Tong, L., Frank, J.
Deposit date:2016-08-31
Release date:2016-10-12
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VHW
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GLUA2-0XGSG1L BOUND TO ZK
Descriptor:Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHX
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GLUA2-1XGSG1L BOUND TO ZK
Descriptor:Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHY
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GLUA2-2XGSG1L BOUND TO ZK
Descriptor:Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHZ
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GLUA2-2XGSG1L BOUND TO L-QUISQUALATE
Descriptor:Glutamate receptor 2,Germ cell-specific gene 1-like protein, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5WEK
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GLUA2 BOUND TO ANTAGONIST ZK AND GSG1L IN DIGITONIN, STATE 1
Descriptor:Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-07-10
Release date:2017-08-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
5WEL
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GLUA2 BOUND TO ANTAGONIST ZK AND GSG1L IN DIGITONIN, STATE 2
Descriptor:Chimera of Glutamate receptor 2, Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, ...
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-07-10
Release date:2017-08-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
5WEM
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GLUA2 BOUND TO GSG1L IN DIGITONIN, STATE 1
Descriptor:Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein
Authors:Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.
Deposit date:2017-07-10
Release date:2017-08-02
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
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