Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1GNR
DownloadVisualize
BU of 1gnr by Molmil
X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE 5'-TRIPHOSPHATE P3-[1-(2-NITROPHENYL)ETHYL ESTER], MAGNESIUM ION
Authors:Scheidig, A, Franken, S.M, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Pai, E.F, Goody, R.S.
Deposit date:1995-05-11
Release date:1995-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp.
J.Mol.Biol., 253, 1995
821P
DownloadVisualize
BU of 821p by Molmil
THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLYCINE-12 MUTANT OF P21H-RAS
Descriptor: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Scheidig, A.J, Krengel, U, Pai, E.F, Kabsch, W, Wittinghofer, A, Goody, R.S.
Deposit date:1993-03-29
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
3C72
DownloadVisualize
BU of 3c72 by Molmil
Engineered RabGGTase in complex with a peptidomimetic inhibitor
Descriptor: CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ...
Authors:Guo, Z, Wu, Y.W, Tan, K.T, Bon, R.S, Guiu-Rozas, E, Delon, C, Nguyen, U.T, Wetzel, S, Arndt, S, Goody, R.S, Blankenfeldt, W, Alexandrov, K, Waldmann, H.
Deposit date:2008-02-06
Release date:2008-07-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
Angew.Chem.Int.Ed.Engl., 47, 2008
5O74
DownloadVisualize
BU of 5o74 by Molmil
Crystal structure of human Rab1b covalently bound to the GEF domain of DrrA/SidM from Legionella pneumophila in the presence of GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Multifunctional virulence effector protein DrrA, Ras-related protein Rab-1B
Authors:Cigler, M, Mueller, T, Horn-Ghetko, D, von Wrisberg, M.K, Fottner, M, Goody, R.S, Itzen, A, Mueller, M.P, Lang, K.
Deposit date:2017-06-08
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo.
Angew. Chem. Int. Ed. Engl., 56, 2017
6FSF
DownloadVisualize
BU of 6fsf by Molmil
Crystal structure of the tandem PX-PH-domains of Bem3 from Saccharomyces cerevisiae
Descriptor: GTPase-activating protein BEM3
Authors:Ali, I, Eu, S, Koch, D, Bleimling, N, Goody, R.S, Mueller, M.P.
Deposit date:2018-02-19
Release date:2018-05-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae.
Acta Crystallogr F Struct Biol Commun, 74, 2018
8A4C
DownloadVisualize
BU of 8a4c by Molmil
Structure of human Rep15:Rab3B complex.
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ...
Authors:Rai, A, Vetter, I.R, Goody, R.S.
Deposit date:2022-06-10
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Nat Commun, 13, 2022
8A4B
DownloadVisualize
BU of 8a4b by Molmil
Structure of human Rep15:Rab3B_Q81L complex.
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab15 effector protein, ...
Authors:Rai, A, Vetter, I.R, Goody, R.S.
Deposit date:2022-06-10
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Nat Commun, 13, 2022
8A4A
DownloadVisualize
BU of 8a4a by Molmil
Structure of human Rep15 in complex with bovine Rab3C.
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ...
Authors:Rai, A, Vetter, I.R, Goody, R.S.
Deposit date:2022-06-10
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Nat Commun, 13, 2022
1QRA
DownloadVisualize
BU of 1qra by Molmil
STRUCTURE OF P21RAS IN COMPLEX WITH GTP AT 100 K
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1
Authors:Scheidig, A, Burmester, C, Goody, R.S.
Deposit date:1999-06-12
Release date:1999-11-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins.
Structure Fold.Des., 7, 1999
1AGP
DownloadVisualize
BU of 1agp by Molmil
THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS
Descriptor: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Franken, S.M, Scheidig, A.J, Wittinghofer, A, Goody, R.S.
Deposit date:1993-03-29
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
4LI0
DownloadVisualize
BU of 4li0 by Molmil
Crystal structure of GDP-bound Rab8:GRAB
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide exchange factor for Rab-3A, Ras-related protein Rab-8A
Authors:Guo, Z, Hou, X.M, Goody, R.S, Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
4LHV
DownloadVisualize
BU of 4lhv by Molmil
Crystal structure of Rab8 in its inactive GDP-bound form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-8A
Authors:Guo, Z, Hou, X.M, Goody, R.S, Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
4LHY
DownloadVisualize
BU of 4lhy by Molmil
Crystal structure of GDP-bound Rab8:Rabin8
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Rab-3A-interacting protein, Ras-related protein Rab-8A, ...
Authors:Guo, Z, Hou, X.M, Goody, R.S, Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
4LHZ
DownloadVisualize
BU of 4lhz by Molmil
Crystal structure of GTP-bound Rab8:Rabin8
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Rab-3A-interacting protein, Ras-related protein Rab-8A
Authors:Guo, Z, Hou, X.M, Goody, R.S, Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
1LTX
DownloadVisualize
BU of 1ltx by Molmil
Structure of Rab Escort Protein-1 in complex with Rab geranylgeranyl transferase and isoprenoid
Descriptor: AAAA, CHLORIDE ION, FARNESYL, ...
Authors:Pylypenko, O, Rak, A, Reents, R, Niculae, A, Thoma, N.H, Waldmann, H, Schlichting, I, Goody, R.S, Alexandrov, K.
Deposit date:2002-05-21
Release date:2003-05-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Rab Escort Protein-1 in Complex with Rab Geranylgeranyltransferase
Mol.Cell, 11, 2003
5LPN
DownloadVisualize
BU of 5lpn by Molmil
Structure of human Rab10 in complex with the bMERB domain of Mical-1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein-methionine sulfoxide oxidase MICAL1, ...
Authors:Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M.
Deposit date:2016-08-14
Release date:2016-08-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
3BW6
DownloadVisualize
BU of 3bw6 by Molmil
Crystal structure of the longin domain of yeast Ykt6
Descriptor: SULFATE ION, Synaptobrevin homolog YKT6
Authors:Pylypenko, O, Schonichen, A, Ludwig, D, Ungermann, C, Goody, R.S, Rak, A, Geyer, M.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding.
J.Mol.Biol., 377, 2008
1PLK
DownloadVisualize
BU of 1plk by Molmil
CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S.
Deposit date:1994-03-13
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.
Acta Crystallogr.,Sect.D, 50, 1994
1PLJ
DownloadVisualize
BU of 1plj by Molmil
CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE 5'-TRIPHOSPHATE P3-[1-(2-NITROPHENYL)ETHYL ESTER], MAGNESIUM ION
Authors:Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S.
Deposit date:1994-03-13
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.
Acta Crystallogr.,Sect.D, 50, 1994
1PLL
DownloadVisualize
BU of 1pll by Molmil
CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE
Authors:Scheidig, A, Sanchez-Llorente, A, Lautwein, A, Pai, E.F, Corrie, J.E.T, Reid, G.P, Wittinghofer, A, Goody, R.S.
Deposit date:1994-03-13
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points.
Acta Crystallogr.,Sect.D, 50, 1994
1VG9
DownloadVisualize
BU of 1vg9 by Molmil
The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-23
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
6ZSH
DownloadVisualize
BU of 6zsh by Molmil
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members
Descriptor: EH domain-binding protein 1
Authors:Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S.
Deposit date:2020-07-15
Release date:2020-09-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Nat Commun, 11, 2020
6ZSI
DownloadVisualize
BU of 6zsi by Molmil
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Descriptor: DI(HYDROXYETHYL)ETHER, EH domain-binding protein 1, MAGNESIUM ION, ...
Authors:Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S.
Deposit date:2020-07-15
Release date:2020-09-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.914 Å)
Cite:The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Nat Commun, 11, 2020
6ZSJ
DownloadVisualize
BU of 6zsj by Molmil
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Descriptor: EH domain-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S.
Deposit date:2020-07-15
Release date:2020-09-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Nat Commun, 11, 2020
4GTS
DownloadVisualize
BU of 4gts by Molmil
Engineered RabGGTase in complex with BMS analogue 16
Descriptor: 5-{(3R)-3-(4-hydroxybenzyl)-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-7-yl}furan-2-carbaldehyde, CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:Guo, Z, Stigter, E.A, Bon, R.S, Waldmann, H, Blankenfeldt, W, Goody, R.S.
Deposit date:2012-08-29
Release date:2012-10-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Development of Selective, Potent RabGGTase Inhibitors
J.Med.Chem., 55, 2012

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon