Author results

4ONF
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FAB FRAGMENT OF 3D6 IN COMPLEX WITH AMYLOID BETA 1-7
Descriptor:3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein
Authors:Feinberg, H., Saldanha, J.W., Diep, L., Goel, A., Widom, A., Veldman, G.M., Weis, W.I., Schenk, D., Basi, G.S.
Deposit date:2014-01-28
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.
Alzheimers Res Ther, 6, 2014
4ONG
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FAB FRAGMENT OF 3D6 IN COMPLEX WITH AMYLOID BETA 1-40
Descriptor:3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ...
Authors:Feinberg, H., Saldanha, J.W., Diep, L., Goel, A., Widom, A., Veldman, G.M., Weis, W.I., Schenk, D., Basi, G.S.
Deposit date:2014-01-28
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.
Alzheimers Res Ther, 6, 2014
4AAI
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THERMOSTABLE PROTEIN FROM HYPERTHERMOPHILIC VIRUS SSV-RH
Descriptor:ORF E73
Authors:Schlenker, C., Goel, A., Tripet, B.P., Menon, S., Lawrence, C.M., Copie, V.
Deposit date:2011-12-02
Release date:2012-01-11
Last modified:2016-11-30
Method:SOLUTION NMR
Cite:Structural Studies of E73 from a Hyperthermophilic Archaeal Virus Identify the "Rh3" Domain, an Elaborated Ribbon-Helix- Helix Motif Involved in DNA Recognition.
Biochemistry, 51, 2012
5I82
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FIRST CRYSTAL STRUCTURE OF E.COLI BASED RECOMBINANT DIPHTHERIA TOXIN MUTANT CRM197
Descriptor:Diphtheria toxin, SULFATE ION, GLYCEROL
Authors:Minasov, G., Shuvalova, L., Mishra, R.P.N., Goel, A., Dubrovska, I., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-02-18
Release date:2016-03-02
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197.
To Be Published
5M11
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STRUCTURAL AND FUNCTIONAL PROBING OF PORZ, AN ESSENTIAL BACTERIAL SURFACE COMPONENT OF THE TYPE-IX SECRETION SYSTEM OF HUMAN ORAL-MICROBIOMIC PORPHYROMONAS GINGIVALIS.
Descriptor:Immunoreactive 84kD antigen PG93, CALCIUM ION, ZINC ION, ...
Authors:Lasica, A.M., Goulas, T., Mizgalska, D., Zhou, X., Ksiazek, M., Madej, M., Guo, Y., Guevara, T., Nowak, M., Potempa, B., Goel, A., Sztukowska, M., Prabhakar, A.T., Bzowska, M., Widziolek, M., Thogersen, I.B., Enghild, J.J., Simonian, M., Kulczyk, A.W., Nguyen, K.-A., Potempa, J., Gomis-Ruth, F.X.
Deposit date:2016-10-07
Release date:2016-11-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.
Sci Rep, 6, 2016
3IFL
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X-RAY STRUCTURE OF AMYLOID BETA PEPTIDE:ANTIBODY (ABETA1-7:12A11) COMPLEX
Descriptor:12A11 FAB antibody light chain, 12A11 FAB antibody heavy chain, Amyloid beta A4 protein
Authors:Weis, W.I., Feinberg, H., Basi, G.S., Schenk, D.
Deposit date:2009-07-24
Release date:2009-11-17
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
3IFN
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X-RAY STRUCTURE OF AMYLOID BETA PEPTIDE:ANTIBODY (ABETA1-40:12A11) COMPLEX
Descriptor:12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein
Authors:Weis, W.I., Feinberg, H., Basi, G.S., Schenk, D.
Deposit date:2009-07-24
Release date:2009-11-17
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
3IFO
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X-RAY STRUCTURE OF AMYLOID BETA PEPTIDE:ANTIBODY (ABETA1-7:10D5) COMPLEX
Descriptor:10D5 FAB antibody heavy chain, 10D5 FAB antibody light chain, Amyloid beta A4 protein
Authors:Weis, W.I., Feinberg, H., Basi, G.S., Schenk, D.
Deposit date:2009-07-24
Release date:2009-11-17
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
3IFP
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X-RAY STRUCTURE OF AMYLOID BETA PEPTIDE:ANTIBODY (ABETA1-7:12B4) COMPLEX
Descriptor:12B4 FAB antibody heavy chain, 12B4 FAB antibody light chain, Amyloid beta A4 protein
Authors:Weis, W.I., Feinberg, H., Basi, G.S., Schenk, D.
Deposit date:2009-07-24
Release date:2009-11-17
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
3UGC
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STRUCTURAL BASIS OF JAK2 INHIBITION BY THE TYPE II INHIBTOR NVP-BBT594
Descriptor:Tyrosine-protein kinase JAK2, 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1H-indole-1-carboxamide, MALONATE ION
Authors:Scheufler, C., Tavares, G.A., Manley, P.W., Pissot-Soldermann, C., Kroemer, M.
Deposit date:2011-11-02
Release date:2012-05-16
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent.
Cancer Discov, 2, 2012
5X57
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STRUCTURE OF GAR DOMAIN OF ACF7
Descriptor:Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, NICKEL (II) ION
Authors:Yang, F., Wang, T., Zhang, Y., Wu, X.Y.
Deposit date:2017-02-15
Release date:2017-07-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics.
Nat Commun, 8, 2017
5ZTN
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THE CRYSTAL STRUCTURE OF HUMAN DYRK2 IN COMPLEX WITH CURCUMIN
Descriptor:Dual specificity tyrosine-phosphorylation-regulated kinase 2, (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
Authors:Ji, C.G., Xiao, J.Y.
Deposit date:2018-05-04
Release date:2018-07-18
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
171588
PDB entries from 2020-11-25