Author results

4AAG
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CRYSTAL STRUCTURE OF THE MUTANT D75N I-CREI IN COMPLEX WITH ITS WILD- TYPE TARGET IN PRESENCE OF CA AT THE ACTIVE SITE (THE FOUR CENTRAL BASES, 2NN REGION, ARE COMPOSED BY GTAC FROM 5' TO 3')
Descriptor:DNA ENDONUCLEASE I-CREI, 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*CP *GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', CALCIUM ION
Authors:Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F., Epinat, J.C., Valton, J., Grizot, S., Duchateau, P., Prieto, J., Montoya, G.
Deposit date:2011-12-01
Release date:2012-05-02
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
3OEZ
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CRYSTAL STRUCTURE OF THE L317I MUTANT OF THE CHICKEN C-SRC TYROSINE KINASE DOMAIN COMPLEXED WITH IMATINIB
Descriptor:Proto-oncogene tyrosine-protein kinase Src, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, ACETATE ION, ...
Authors:Boubeva, R., Pernot, L., Perozzo, R., Scapozza, L.
Deposit date:2010-08-13
Release date:2011-08-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation
To be Published
3OF0
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CRYSTAL STRUCTURE OF THE L317I MUTANT OF THE CHICKEN C-SRC TYROSINE KINASE DOMAIN
Descriptor:Proto-oncogene tyrosine-protein kinase Src
Authors:Boubeva, R., Pernot, L., Perozzo, R., Scapozza, L.
Deposit date:2010-08-13
Release date:2011-08-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation
To be Published
3QLF
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CRYSTAL STRUCTURE OF THE L317I MUTANT OF THE C-SRC TYROSINE KINASE DOMAIN COMPLEXED WITH PYRAZOLOPYRIMIDINE 5
Descriptor:Proto-oncogene tyrosine-protein kinase Src, 1-{4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea
Authors:Boubeva, R., Pernot, L., Perozzo, R., Scapozza, L.
Deposit date:2011-02-02
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation
To be Published
3QLG
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CRYSTAL STRUCTURE OF THE L317I MUTANT OF THE C-SRC TYROSINE KINASE DOMAIN COMPLEXED WITH DASATINIB
Descriptor:Proto-oncogene tyrosine-protein kinase Src, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
Authors:Boubeva, R., Pernot, L., Perozzo, R., Scapozza, L.
Deposit date:2011-02-02
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation
To be Published