8QZJ
| |
8QZI
| Crystal structure of PptT-ACP from Mycobacterium tuberculosis | Descriptor: | 4'-phosphopantetheinyl transferase PptT, COENZYME A, ISOPROPYL ALCOHOL, ... | Authors: | Gavalda, S, Mourey, L, Pedelacq, J.D. | Deposit date: | 2023-10-27 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases Acs Catalysis, 14, 2024
|
|
8QZH
| Crystal structure of apo-PptT from Mycobacterium tuberculosis | Descriptor: | 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION | Authors: | Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2023-10-27 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases Acs Catalysis, 14, 2024
|
|
8OTA
| High resolution crystal structure of a Leaf-branch compost cutinase quadruple variant | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Leaf-branch compost cutinase | Authors: | Gavalda, S, Cioci, G, Marty, A, Duquesne, S. | Deposit date: | 2023-04-20 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Exploring the pH dependence of an improved PETase. Biophys.J., 123, 2024
|
|
5NJI
| Structure of the dehydratase domain of PpsC from Mycobacterium tuberculosis in complex with C12:1-CoA | Descriptor: | Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (~{E})-dodec-2-enethioate | Authors: | Gavalda, S, Faille, A, Mourey, L, Pedelacq, J.D. | Deposit date: | 2017-03-28 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. J. Mol. Biol., 429, 2017
|
|
8C4X
| PAM Protease | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Nomme, J, Gavalda, S, Cioci, G, Guicherd, M, Marty, A, Duquesne, S, Ben Khaled, M. | Deposit date: | 2023-01-05 | Release date: | 2024-07-17 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | An engineered enzyme embedded into PLA to make self-biodegradable plastic. Nature, 631, 2024
|
|
8C4Z
| ProteinT protease, inactive mutant S224A | Descriptor: | CALCIUM ION, Extracellular serine proteinase, GLYCEROL, ... | Authors: | Nomme, J, Gavalda, S, Cioci, G, Guicherd, M, Marty, A, Duquesne, S, Ben Khaled, M. | Deposit date: | 2023-01-05 | Release date: | 2024-07-17 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | An engineered enzyme embedded into PLA to make self-biodegradable plastic. Nature, 631, 2024
|
|
5L84
| |
6THT
| |
6THS
| |
7AGR
| |
5I0K
| |
4U89
| |
7AGS
| |
7AGP
| Structure of the AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, Mycocerosic acid synthase | Authors: | Brison, Y, Nahoum, V, Mourey, L, Maveyraud, L. | Deposit date: | 2020-09-23 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
|
|
7AGQ
| |
7AHB
| Acyltransferase domain of the polyketide synthase PpsC of Mycobacterium tuberculosis | Descriptor: | GLYCEROL, Phthiocerol synthesis polyketide synthase type I PpsC, SODIUM ION, ... | Authors: | Faille, A, Mourey, L, Pedelacq, J.D. | Deposit date: | 2020-09-24 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
|
|
7AKC
| Structure of the of AcylTransferase domain of phenolphthiocerol/phtiocerol synthase A from Mycobacterium bovis (BCG) | Descriptor: | Phenolpthiocerol synthesis type-I polyketide synthase ppsA, SODIUM ION | Authors: | Brison, Y, Nahoum, V, Mourey, L, Maveyraud, L. | Deposit date: | 2020-09-30 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
|
|
7AGU
| Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated with MethylMalonyl-coenzyme A | Descriptor: | 1,2-ETHANEDIOL, METHYLMALONIC ACID, Mycocerosic acid synthase | Authors: | Brison, Y, Mourey, L, Maveyraud, L. | Deposit date: | 2020-09-23 | Release date: | 2020-12-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
|
|
7AGT
| |
6QWU
| 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 5.5 with Mn2+ and CoA. | Descriptor: | COENZYME A, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2019-03-06 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
|
|
6QXQ
| |
6QXR
| 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mn2+ and CoA. | Descriptor: | CALCIUM ION, COENZYME A, MANGANESE (II) ION, ... | Authors: | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2019-03-07 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
|
|
6RCX
| Mycobacterial 4'-phosphopantetheinyl transferase PptAb in complex with the ACP domain of PpsC. | Descriptor: | CACODYLATE ION, COENZYME A, MANGANESE (II) ION, ... | Authors: | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | Deposit date: | 2019-04-12 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
|
|
6QYG
| |