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5NJI
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STRUCTURE OF THE DEHYDRATASE DOMAIN OF PPSC FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH C12:1-COA
Descriptor:Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (~{E})-dodec-2-enethioate
Authors:Gavalda, S., Faille, A., Mourey, L., Pedelacq, J.D.
Deposit date:2017-03-28
Release date:2017-05-31
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.
J. Mol. Biol., 429, 2017
5L84
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STRUCTURE OF THE H959F VARIANT OF THE PPSC DEHYDRATASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Phthiocerol synthesis polyketide synthase type I PpsC
Authors:Faille, A., Gavalda, S., Mourey, L., Pedelacq, J.D.
Deposit date:2016-06-07
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.
J. Mol. Biol., 429, 2017
2PTW
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH SULPHATE, IDENTIFICATION OF A METAL BINDING SITE IV
Descriptor:Enolase, ZINC ION, SULFATE ION, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTX
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH SULPHATE IN CLOSED CONFORMATION
Descriptor:Enolase, ZINC ION, SULFATE ION, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTY
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH PEP
Descriptor:Enolase, ZINC ION, PHOSPHOENOLPYRUVATE, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTZ
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH PHOSPHONOACETOHYDROXAMATE (PAH), HIS156-OUT CONFORMATION
Descriptor:Enolase, ZINC ION, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU0
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH PHOSPHONOACETOHYDROXAMATE (PAH), HIS156-IN CONFORMATION
Descriptor:Enolase, ZINC ION, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU1
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CRYSTAL STRUCTURE OF THE T. BRUCEI ENOLASE COMPLEXED WITH FLUORO-PHOSPHONOACETOHYDROXAMATE (FPAH)
Descriptor:Enolase, ZINC ION, [(1S)-1-FLUORO-2-(HYDROXYAMINO)-2-OXOETHYL]PHOSPHONIC ACID, ...
Authors:Navarro, M.V.A.S., Rigden, D.J., Garratt, R.C., Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
3TZW
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CRYSTAL STRUCTURE OF A FRAGMENT CONTAINING THE ACYLTRANSFERASE DOMAIN OF PKS13 FROM MYCOBACTERIUM TUBERCULOSIS IN THE ORTHORHOMBIC APOFORM AT 2.6 A
Descriptor:Polyketide synthase PKS13, 12-mer peptide, SULFATE ION, ...
Authors:Bergeret, F., Pedelacq, J.D., Mourey, L., Bon, C.
Deposit date:2011-09-28
Release date:2012-08-29
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
J.Biol.Chem., 287, 2012
3TZX
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CRYSTAL STRUCTURE OF A FRAGMENT CONTAINING THE ACYLTRANSFERASE DOMAIN OF PKS13 FROM MYCOBACTERIUM TUBERCULOSIS IN TETRAGONAL APO FORM AT 2.3 A
Descriptor:Polyketide synthase PKS13, 12-mer peptide, GLYCEROL, ...
Authors:Bergeret, F., Pedelacq, J.D., Mourey, L., Bon, C.
Deposit date:2011-09-28
Release date:2012-08-29
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
J.Biol.Chem., 287, 2012
3TZY
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CRYSTAL STRUCTURE OF A FRAGMENT CONTAINING THE ACYLTRANSFERASE DOMAIN OF PKS13 FROM MYCOBACTERIUM TUBERCULOSIS IN THE PALMITOYLATED FORM AT 2.2 A
Descriptor:Polyketide synthase PKS13, 12-mer peptide, PALMITIC ACID, ...
Authors:Bergeret, F., Pedelacq, J.D., Mourey, L., Bon, C.
Deposit date:2011-09-28
Release date:2012-08-29
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
J.Biol.Chem., 287, 2012
3TZZ
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CRYSTAL STRUCTURE OF A FRAGMENT CONTAINING THE ACYLTRANSFERASE DOMAIN OF PKS13 FROM MYCOBACTERIUM TUBERCULOSIS IN THE CARBOXYPALMITOYLATED FORM AT 2.5 A
Descriptor:Polyketide synthase PKS13, 12-mer peptide, tetradecylpropanedioic acid, ...
Authors:Bergeret, F., Pedelacq, J.D., Mourey, L., Bon, C.
Deposit date:2011-09-28
Release date:2012-08-29
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13
J.Biol.Chem., 287, 2012
4U89
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4'-PHOSPHOPANTETHEINYL TRANSFERASE PPTT FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Phosphopantetheinyl transferase PptT, COENZYME A, SODIUM ION, ...
Authors:Faille, A., Mourey, L., Pedelacq, J.D.
Deposit date:2014-08-01
Release date:2015-08-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-ray structure of the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
to be published
5I0K
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INSIGHTS INTO SUBSTRATE MODIFICATION BY DEHYDRATASES FROM TYPE I POLYKETIDE SYNTHASES
Descriptor:Phthiocerol synthesis polyketide synthase type I PpsC, CROTONYL COENZYME A
Authors:Faille, A., Mourey, L., Pedelacq, J.D.
Deposit date:2016-02-04
Release date:2017-08-09
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.
J. Mol. Biol., 429, 2017