Author results

4MOD
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STRUCTURE OF THE MERS-COV FUSION CORE
Descriptor:HR1 of S protein, LINKER, HR2 of S protein
Authors:Gao, J., Lu, G., Qi, J., Li, Y., Wu, Y., Deng, Y., Geng, H., Xiao, H., Tan, W., Yan, J., Gao, G.F.
Deposit date:2013-09-12
Release date:2013-10-09
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structure of the fusion core and inhibition of fusion by a heptad-repeat peptide derived from the S protein of MERS-CoV
J.Virol., 2013
1BO9
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NMR SOLUTION STRUCTURE OF DOMAIN 1 OF HUMAN ANNEXIN I
Descriptor:PROTEIN (ANNEXIN I)
Authors:Gao, J., Yan Li, H.
Deposit date:1998-08-10
Release date:1998-08-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of domain 1 of human annexin I shows an autonomous folding unit.
J.Biol.Chem., 274, 1999
4KS7
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PAK6 KINASE DOMAIN IN COMPLEX WITH PF-3758309
Descriptor:Serine/threonine-protein kinase PAK 6, ISOPROPYL ALCOHOL, PF-3758309
Authors:Gao, J., Boggon, T.J.
Deposit date:2013-05-17
Release date:2013-09-11
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6.
Plos One, 8, 2013
4KS8
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PAK6 KINASE DOMAIN IN COMPLEX WITH SUNITINIB
Descriptor:Serine/threonine-protein kinase PAK 6, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Authors:Gao, J., Boggon, T.J.
Deposit date:2013-05-17
Release date:2013-09-11
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6.
Plos One, 8, 2013
5GLX
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE FROM THIELAVIA TERRESTRIS NRRL 8126
Descriptor:Glycoside hydrolase family 45 protein
Authors:Gao, J., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
Deposit date:2016-07-12
Release date:2017-04-19
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GLY
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE IN COMPLEX WITH CELLOTETROSE FROM THIELAVIA TERRESTRIS NRRL 8126
Descriptor:Glycoside hydrolase family 45 protein, beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranose, CELLOTRIOSE
Authors:Gao, J., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
Deposit date:2016-07-12
Release date:2017-04-19
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GM9
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE IN COMPLEX WITH CELLOBIOSE
Descriptor:Glycoside hydrolase family 45 protein, 4-O-beta-D-glucopyranosyl-alpha-D-glucopyranose, CELLOBIOSE
Authors:Gao, J., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
Deposit date:2016-07-13
Release date:2017-04-19
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5ZHE
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STRUCTURE OF E. COLI UNDECAPRENYL DIPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-981
Descriptor:Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), 2-hydroxy-6-(tetradecyloxy)benzoic acid
Authors:Gao, J., Liu, W.D., Zheng, Y.Y., Ko, T.P., Chen, C.C., Guo, R.T.
Deposit date:2018-03-13
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:STRUCTURE OF E. COLI UNDECAPRENYL DIPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-981
to be published
5ZX9
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CRYSTAL STRUCTURE OF A PROTEIN FROM MYCOBACTERIUM
Descriptor:Alanine and proline-rich secreted protein Apa, GLYCEROL
Authors:Gao, J., Liu, W.D., Chen, C.C., Guo, R.T.
Deposit date:2018-05-18
Release date:2019-05-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of a protein from Mycobacterium tuberculosis
to be published
5ZXA
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CRYSTAL STRUCTURE OF A PROTEIN MUTANT FROM MYCOBACTERIUM
Descriptor:Alanine and proline-rich secreted protein Apa, MERCURY (II) ION, GLYCEROL
Authors:Gao, J., Liu, W.D., Chen, C.C., Guo, R.T.
Deposit date:2018-05-18
Release date:2019-05-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of a protein mutant from Mycobacterium tuberculosis
to be published
5XK3
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CRYSTAL STRUCTURE OF APO FORM ISOSESQUILAVANDULYL DIPHOSPHATE SYNTHASE FROM STREPTOMYCES SP. STRAIN CNH-189
Descriptor:Undecaprenyl diphosphate synthase, SULFATE ION
Authors:Ko, T.P., Guo, R.T., Liu, W., Chen, C.C., Gao, J.
Deposit date:2017-05-05
Release date:2018-01-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XK6
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STRUCTURE OF A PRENYLTRANSFERASE SOAKED WITH IPP
Descriptor:Undecaprenyl diphosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Ko, T.P., Guo, R.T., Liu, W., Chen, C.C., Gao, J.
Deposit date:2017-05-05
Release date:2018-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XK7
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CRYSTAL STRUCTURE OF ISOSESQUILAVANDULYL DIPHOSPHATE SYNTHASE FROM STREPTOMYCES SP. STRAIN CNH-189 IN COMPLEX WITH DMAPP
Descriptor:Undecaprenyl diphosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Ko, T.P., Guo, R.T., Liu, W., Chen, C.C., Gao, J.
Deposit date:2017-05-05
Release date:2018-01-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XK8
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CRYSTAL STRUCTURE OF ISOSESQUILAVANDULYL DIPHOSPHATE SYNTHASE FROM STREPTOMYCES SP. STRAIN CNH-189 IN COMPLEX WITH GPP
Descriptor:Undecaprenyl diphosphate synthase, GERANYL DIPHOSPHATE, MAGNESIUM ION
Authors:Ko, T.P., Guo, R.T., Liu, W., Chen, C.C., Gao, J.
Deposit date:2017-05-05
Release date:2018-01-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XK9
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CRYSTAL STRUCTURE OF ISOSESQUILAVANDULYL DIPHOSPHATE SYNTHASE FROM STREPTOMYCES SP. STRAIN CNH-189 IN COMPLEX WITH GSPP AND DMAPP
Descriptor:Undecaprenyl diphosphate synthase, MAGNESIUM ION, GERANYL S-THIOLODIPHOSPHATE, ...
Authors:Ko, T.P., Guo, R.T., Liu, W., Chen, C.C., Gao, J.
Deposit date:2017-05-05
Release date:2018-01-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.137 Å)
Cite:"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.
Angew. Chem. Int. Ed. Engl., 57, 2018
3WYI
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STRUCTURE OF S. AUREUS UNDECAPRENYL DIPHOSPHATE SYNTHASE
Descriptor:Isoprenyl transferase, MAGNESIUM ION
Authors:Gao, J., Ko, T.P., Huang, C.H., Oldfield, E., Guo, R.T.
Deposit date:2014-08-29
Release date:2015-02-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibacterial Drug Leads: DNA and Enzyme Multitargeting.
J.Med.Chem., 2015
3WYJ
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STRUCTURE OF E. COLI UNDECAPRENYL DIPHOSPHATE SYNTHASE IN COMPLEX WITH BPH-789
Descriptor:Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), [1-oxidanyl-2-[3-[3-[[3-[[3-[3-(2-oxidanyl-2,2-diphosphono-ethyl)phenyl]phenyl]sulfamoyl]phenyl]sulfonylamino]phenyl]phenyl]-1-phosphono-ethyl]phosphonic acid
Authors:Gao, J., Ko, T.P., Huang, C.H., Oldfield, E., Guo, R.T.
Deposit date:2014-08-29
Release date:2015-02-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antibacterial Drug Leads: DNA and Enzyme Multitargeting.
J.Med.Chem., 2015
5YGJ
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CRYSTAL STRUCTURE OF A SYNTHASE FROM STREPTOMYCES SP. CL190
Descriptor:Cyclolavandulyl diphosphate synthase
Authors:Gao, J., Liu, W.D., Chen, C.C., Guo, R.T.
Deposit date:2017-09-23
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Crystal structure of a synthase from Streptomyces sp. CL190
Acs Catalysis, 8, 2018
5YGK
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CRYSTAL STRUCTURE OF A SYNTHASE FROM STREPTOMYCES SP. CL190 WITH DMASPP
Descriptor:Cyclolavandulyl diphosphate synthase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION
Authors:Gao, J., Liu, W.D., Chen, C.C., Guo, R.T.
Deposit date:2017-09-23
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Crystal structure of a synthase from Streptomyces sp. CL190
Acs Catalysis, 8, 2018
3MFQ
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A GLANCE INTO THE METAL BINDING SPECIFICITY OF TROA: WHERE ELABORATE BEHAVIORS OCCUR IN THE ACTIVE CENTER
Descriptor:High-affinity zinc uptake system protein znuA, ZINC ION
Authors:Gao, G.F., Zheng, B., Zhang, Q., Gao, J., Han, H., Li, M.
Deposit date:2010-04-03
Release date:2011-04-13
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Insight into the interaction of metal ions with TroA from Streptococcus suis
Plos One, 6, 2011
1Q5X
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STRUCTURE OF OF RRAA (MENG), A PROTEIN INHIBITOR OF RNA PROCESSING
Descriptor:REGULATOR OF RNASE E ACTIVITY A
Authors:Monzingo, A.F., Gao, J., Qiu, J., Georgiou, G., Robertus, J.D.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003
1OS5
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CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A NOVEL NON-COMPETITIVE INHIBITOR.
Descriptor:Hepatitis C virus NS5B RNA polymerase, 3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE
Authors:Love, R.A., Parge, H.E., Yu, X., Hickey, M.J., Diehl, W., Gao, J., Wriggers, H., Ekker, A., Wang, L., Thomson, J.A., Dragovich, P.S., Fuhrman, S.A.
Deposit date:2003-03-18
Release date:2004-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme.
J.Virol., 77, 2003
4QNP
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CRYSTAL STRUCTURE OF THE 2009 PANDEMIC H1N1 INFLUENZA VIRUS NEURAMINIDASE WITH A NEUTRALIZING ANTIBODY
Descriptor:Neuraminidase, neutralizing antibody, light chain, ...
Authors:Wan, H.Q., Yang, H., Shore, D.A., Garten, R.J., Couzens, L., Gao, J., Jiang, L.L., Carney, P.J., Villanueva, J., Stevens, J., Eichelberger, M.C.
Deposit date:2014-06-18
Release date:2015-02-11
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers.
Nat Commun, 6, 2015
1Z9M
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CRYSTAL STRUCTURE OF NECTIN-LIKE MOLECULE-1 PROTEIN DOMAIN 1
Descriptor:GAPA225
Authors:Dong, X., Xu, F., Gong, Y., Gao, J., Lin, P., Chen, T., Peng, Y., Qiang, B., Yuan, J., Peng, X., Rao, Z.
Deposit date:2005-04-03
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the V Domain of Human Nectin-like Molecule-1/Syncam3/Tsll1/Igsf4b, a Neural Tissue-specific Immunoglobulin-like Cell-Cell Adhesion Molecule
J.Biol.Chem., 281, 2006
2IS9
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STRUCTURE OF YEAST DCN-1
Descriptor:Defective in cullin neddylation protein 1, PLATINUM (II) ION, CHLORIDE ION, ...
Authors:Yang, X., Zhou, J., Sun, L., Wei, Z., Gao, J., Gong, W., Xu, R.M., Rao, Z., Liu, Y.
Deposit date:2006-10-16
Release date:2007-06-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the function of DCN-1 in protein Neddylation.
J.Biol.Chem., 282, 2007