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1H15
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BU of 1h15 by Molmil
X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ...
Authors:Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L.
Deposit date:2002-07-02
Release date:2002-10-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3, 2002
2XPG
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BU of 2xpg by Molmil
Crystal structure of a MHC class I-peptide complex
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-3 ALPHA CHAIN, ...
Authors:McMahon, R.M, Friis, L, Siebold, C, Friese, M.A, Fugger, L, Jones, E.Y.
Deposit date:2010-08-26
Release date:2011-04-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Hla-A0301 in Complex with a Peptide of Proteolipid Protein: Insights Into the Role of Hla-A Alleles in Susceptibility to Multiple Sclerosis
Acta Crystallogr.,Sect.D, 67, 2011
2WBJ
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BU of 2wbj by Molmil
TCR complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
Authors:Harkiolaki, M, Holmes, S.L, Svendsen, P, Gregersen, J.W, Jensen, L.T, McMahon, R, Friese, M.A, van Boxel, G, Etzensperger, R, Tzartos, J.S, Kranc, K, Sainsbury, S, Harlos, K, Mellins, E.D, Palace, J, Esiri, M.M, van der Merwe, P.A, Jones, E.Y, Fugger, L.
Deposit date:2009-03-02
Release date:2009-04-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Immunity, 30, 2009
1UVQ
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BU of 1uvq by Molmil
Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, GLYCINE, ...
Authors:Siebold, C, Hansen, B.E, Wyer, J.R, Harlos, K, Esnouf, R.E, Svejgaard, A, Bell, J.I, Strominger, J.L, Jones, E.Y, Fugger, L.
Deposit date:2004-01-22
Release date:2004-02-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
Proc.Natl.Acad.Sci.USA, 101, 2004
3MFF
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BU of 3mff by Molmil
1F1E8hu TCR
Descriptor: ARGININE, GLYCEROL, T cell receptor alpha chain, ...
Authors:van Boxel, G.I, Holmes, S, Fugger, L, Jones, E.Y.
Deposit date:2010-04-02
Release date:2010-06-02
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:An alternative conformation of the T-cell receptor alpha constant region
J.Mol.Biol., 400, 2010
6VQ2
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BU of 6vq2 by Molmil
HLA-B*27:05 presenting an HIV-1 14mer peptide
Descriptor: 14-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
Authors:Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
Deposit date:2020-02-04
Release date:2021-02-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQE
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BU of 6vqe by Molmil
HLA-B*27:05 presenting an HIV-1 13mer peptide
Descriptor: 13-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
Authors:Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
Deposit date:2020-02-05
Release date:2021-02-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQZ
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BU of 6vqz by Molmil
HLA-B*27:05 presenting an HIV-1 6mer peptide
Descriptor: 6-mer peptide, ARGININE, Beta-2-microglobulin, ...
Authors:Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
Deposit date:2020-02-06
Release date:2021-02-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VPZ
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BU of 6vpz by Molmil
HLA-B*27:05 presenting an HIV-1 11mer peptide
Descriptor: 11-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
Authors:Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
Deposit date:2020-02-04
Release date:2021-02-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQD
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BU of 6vqd by Molmil
HLA-B*27:05 presenting an HIV-1 8mer peptide
Descriptor: 8-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
Authors:Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
Deposit date:2020-02-05
Release date:2021-02-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQY
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BU of 6vqy by Molmil
HLA-B*27:05 presenting an HIV-1 7mer peptide
Descriptor: 7-mer peptide, ARGININE, Beta-2-microglobulin, ...
Authors:Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
Deposit date:2020-02-06
Release date:2021-02-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
2C7U
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BU of 2c7u by Molmil
Conflicting selective forces affect CD8 T-cell receptor contact sites in an HLA-A2 immunodominant HIV epitope.
Descriptor: BETA-2-MICROGLOBULIN, GAG PROTEIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Iversen, A.K, Stewart-Jones, G, Learn, G.H, Christie, N, Sylvester-Hviid, C, Armitage, A.E, Kaul, R, Beattie, T, Lee, J.K, Li, Y, Chotiyarnwong, P, Dong, T, Xu, X, Luscher, M.A, MacDonald, K, Ullum, H, Klarlund-Pedersen, B, Skinhoj, P, Fugger, J.L, Buus, S, Mullins, J.I, Jones, E.Y, van der Merwe, P.A, McMichael, A.J.
Deposit date:2005-11-29
Release date:2006-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.
Nat.Immunol., 7, 2006
5HEZ
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BU of 5hez by Molmil
JAK2 kinase (JH1 domain) mutant P1057A in complex with TG101209
Descriptor: CHLORIDE ION, N-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide, Tyrosine-protein kinase JAK2, ...
Authors:Ultsch, M, Eigenbrot, C.
Deposit date:2016-01-06
Release date:2016-11-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Sci Transl Med, 8, 2016
8EQ6
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BU of 8eq6 by Molmil
PD1 signaling receptor bound to FAB Complex
Descriptor: Antibody FAB heavy chain, Antibody FAB light chain, Programmed cell death protein 1
Authors:Bjorkelid, C, Paluch, C, Robertson, N.J.
Deposit date:2022-10-07
Release date:2023-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Immunity, 57, 2024
3GIV
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BU of 3giv by Molmil
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Descriptor: Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ...
Authors:Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y.
Deposit date:2009-03-06
Release date:2009-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
5V4N
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BU of 5v4n by Molmil
Structure of HLA-DR1 with bound alpha3(135-145) peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01
Authors:Petersen, J, Rossjohn, J.
Deposit date:2017-03-10
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
5V4M
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BU of 5v4m by Molmil
Structure of HLA-DR15 with bound alpha3(135-145) peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ...
Authors:Petersen, J, Rossjohn, J.
Deposit date:2017-03-10
Release date:2017-05-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
5VGE
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BU of 5vge by Molmil
Crystal structure of HLA-C*07:02 in complex with RYR peptide
Descriptor: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, ZINC ION, ...
Authors:Mobbs, J.I, Vivian, J.P, Gras, S, Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
5VGD
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BU of 5vgd by Molmil
Crystal Structure of HLA-C*0501 in complex with SAE
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-5 alpha chain, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-04-11
Release date:2017-05-31
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017

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