8B0X
 
 | | Translating 70S ribosome in the unrotated state (P and E, tRNAs) | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Fromm, S.A, O'Connor, K.M, Purdy, M, Bhatt, P.R, Loughran, G, Atkins, J.F, Jomaa, A, Mattei, S. | | Deposit date: | 2022-09-08 | | Release date: | 2022-11-30 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (1.55 Å) | | Cite: | The translating bacterial ribosome at 1.55 angstrom resolution generated by cryo-EM imaging services.
Nat Commun, 14, 2023
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4UDV
 | | Cryo-EM structure of TMV at 3.35 A resolution | | Descriptor: | 5'-D(*GP*AP*AP)-3', CAPSID PROTEIN | | Authors: | Fromm, S.A, Bharat, T.A.M, Jakobi, A.J, Hagen, W.J.H, Sachse, C. | | Deposit date: | 2014-12-11 | | Release date: | 2014-12-31 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Seeing Tobacco Mosaic Virus Through Direct Electron Detectors.
J.Struct.Biol., 189, 2015
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4A53
 | | Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6 | | Descriptor: | EDC3 | | Authors: | Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R. | | Deposit date: | 2011-10-24 | | Release date: | 2012-02-01 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
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4A54
 | | Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6 | | Descriptor: | EDC3, MRNA DECAPPING COMPLEX SUBUNIT 2 | | Authors: | Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R. | | Deposit date: | 2011-10-24 | | Release date: | 2012-02-01 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
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6WJ3
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6WJ2
 | | CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state | | Descriptor: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Fromm, S.A, Hurley, J.H. | | Deposit date: | 2020-04-11 | | Release date: | 2020-09-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.
Nat.Struct.Mol.Biol., 27, 2020
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6NZD
 | | Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | | Descriptor: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | | Authors: | Fromm, S.A, Young, L.N, Hurley, J.H. | | Deposit date: | 2019-02-13 | | Release date: | 2019-11-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Science, 366, 2019
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7Z0O
 | | Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA | | Descriptor: | Histone H3, Histone H4, Non-template DNA, ... | | Authors: | Baudin, F, Murciano, B, Fung, H.K.H, Fromm, S.A, Mueller, C.W. | | Deposit date: | 2022-02-23 | | Release date: | 2022-04-27 | | Last modified: | 2022-05-04 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanism of RNA polymerase I selection by transcription factor UAF.
Sci Adv, 8, 2022
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4Q2S
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8AFW
 | | Tube assembly of Atg18-WT | | Descriptor: | Autophagy-related protein 18 | | Authors: | Mann, D, Fromm, S, Martinez-Sanchez, A, Gopaldass, N, Mayer, A, Sachse, C. | | Deposit date: | 2022-07-18 | | Release date: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structures of Atg18 oligomers reveal a tilted structural scaffold for Atg2 at the isolation membrane
To Be Published
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8AFQ
 | | Tube assembly of Atg18-PR72AA | | Descriptor: | Autophagy-related protein 18 | | Authors: | Mann, D, Fromm, S, Martinez-Sanchez, A, Gopaldass, N, Mayer, A, Sachse, C. | | Deposit date: | 2022-07-18 | | Release date: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of Atg18 oligomers reveal a tilted structural scaffold for Atg2 at the isolation membrane
To Be Published
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8AFY
 | | Subtomogram average of membrane-bound Atg18 oligomers | | Descriptor: | Autophagy-related protein 18 | | Authors: | Mann, D, Fromm, S, Martinez-Sanchez, A, Gopaldass, N, Mayer, A, Sachse, C. | | Deposit date: | 2022-07-18 | | Release date: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (26 Å) | | Cite: | Cryo-EM structures of Atg18 oligomers reveal a tilted structural scaffold for Atg2 at the isolation membrane
To Be Published
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8AFX
 | | Single particle structure of Atg18-WT | | Descriptor: | Autophagy-related protein 18 | | Authors: | Mann, D, Fromm, S, Martinez-Sanchez, A, Gopaldass, N, Mayer, A, Sachse, C. | | Deposit date: | 2022-07-18 | | Release date: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Cryo-EM structures of Atg18 oligomers reveal a tilted structural scaffold for Atg2 at the isolation membrane
To Be Published
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8DHB
 | | Active FLCN GAP complex | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Folliculin, Folliculin-interacting protein 2, ... | | Authors: | Jansen, R.M, Hurley, J.H. | | Deposit date: | 2022-06-25 | | Release date: | 2022-09-28 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation.
Sci Adv, 8, 2022
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7MGE
 | | Structure of C9orf72:SMCR8:WDR41 in complex with ARF1 | | Descriptor: | ADP-ribosylation factor 1, BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Su, M.-Y, Hurley, J.H. | | Deposit date: | 2021-04-12 | | Release date: | 2021-06-23 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Structural basis for the ARF GAP activity and specificity of the C9orf72 complex.
Nat Commun, 12, 2021
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6V4U
 | | Cryo-EM structure of SMCR8-C9orf72-WDR41 complex | | Descriptor: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | | Authors: | Su, M.Y, Hurley, J.H. | | Deposit date: | 2019-12-01 | | Release date: | 2020-09-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD.
Nature, 585, 2020
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