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5E5A
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CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
Descriptor:DNA (146-MER), Histone H3.2, Histone H4, ...
Authors:Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
Deposit date:2015-10-08
Release date:2016-02-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
6NCL
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NEAR-ATOMIC STRUCTURE OF ICOSAHEDRALLY AVERAGED PBCV-1 CAPSID
Descriptor:P14, P9, P10, ...
Authors:Fang, Q., Rossmann, M.G.
Deposit date:2018-12-11
Release date:2019-01-30
Last modified:2019-02-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic structure of a giant virus.
Nat Commun, 10, 2019
5ZVS
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STRUCTURE OF RNA POLYMERASE COMPLEX AND GENOME WITHIN A DSRNA VIRUS PROVIDES INSIGHTS INTO THE MECHANISMS OF TRANSCRIPTION AND ASSEMBLY
Descriptor:VP3, VP2, Putative core protein NTPase/VP5
Authors:Liu, H., Fang, Q., Cheng, L.
Deposit date:2018-05-12
Release date:2018-07-04
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZVT
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STRUCTURE OF RNA POLYMERASE COMPLEX AND GENOME WITHIN A DSRNA VIRUS PROVIDES INSIGHTS INTO THE MECHANISMS OF TRANSCRIPTION AND ASSEMBLY
Descriptor:Outer capsid VP7, N-terminus of outer capsid protein VP5, C-terminus of outer capsid protein VP5, ...
Authors:Liu, H., Fang, Q., Cheng, L.
Deposit date:2018-05-12
Release date:2018-07-04
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3EP3
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HUMAN ADOMETDC D174N MUTANT WITH NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP4
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HUMAN ADOMETDC E256Q MUTANT WITH NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP5
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HUMAN ADOMETDC E178Q MUTANT WITH NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP6
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HUMAN ADOMETDC D174N MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP7
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HUMAN ADOMETDC E256Q MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP8
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HUMAN ADOMETDC E178Q MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EP9
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HUMAN ADOMETDC WITH NO PUTRESCINE BOUND
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EPA
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HUMAN ADOMETDC E178Q MUTANT COMPLEXED WITH PUTRESCINE
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3EPB
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HUMAN ADOMETDC E256Q MUTANT COMPLEXED WITH PUTRESCINE
Descriptor:S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 1,4-DIAMINOBUTANE, ...
Authors:Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-12-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
3IYL
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ATOMIC CRYOEM STRUCTURE OF A NONENVELOPED VIRUS SUGGESTS HOW MEMBRANE PENETRATION PROTEIN IS PRIMED FOR CELL ENTRY
Descriptor:Outer capsid VP4, Core protein VP6, VP1, ...
Authors:Zhang, X., Jin, L., Fang, Q., Hui, W., Zhou, Z.H.
Deposit date:2010-02-02
Release date:2010-05-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.
Cell(Cambridge,Mass.), 141, 2010
3K1Q
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BACKBONE MODEL OF AN AQUAREOVIRUS VIRION BY CRYO-ELECTRON MICROSCOPY AND BIOINFORMATICS
Descriptor:VP1, VP3A, VP3B, ...
Authors:Cheng, L.P., Zhu, J., Hiu, W.H., Zhang, X.K., Honig, B., Fang, Q., Zhou, Z.H.
Deposit date:2009-09-28
Release date:2010-03-23
Last modified:2015-01-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Backbone Model of an Aquareovirus Virion by Cryo-Electron Microscopy and Bioinformatics
J.Mol.Biol., 397, 2010
4KUD
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED SIR3 BAH DOMAIN D205N MUTANT IN COMPLEX WITH YEAST NUCLEOSOME CORE PARTICLE
Descriptor:Histone H3, Histone H4, Histone H2A.2, ...
Authors:Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4KUI
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN
Descriptor:Regulatory protein SIR3, ISOPROPYL ALCOHOL, ACETIC ACID
Authors:Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4KUL
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CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN V83P MUTANT
Descriptor:Regulatory protein SIR3
Authors:Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
4PH4
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THE CRYSTAL STRUCTURE OF HUMAN VPS34 IN COMPLEX WITH PIK-III
Descriptor:Phosphatidylinositol 3-kinase catalytic subunit type 3, GLYCEROL, 4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine
Authors:Knapp, M.S., Elling, R.A.
Deposit date:2014-05-04
Release date:2014-10-29
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat.Cell Biol., 16, 2014
4PSW
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
Descriptor:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4 type VIII, ...
Authors:Yang, M., Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
4PSX
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CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX
Descriptor:Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4, ...
Authors:Yang, M., Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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