6NQD | |
6NCL | |
5ZVS | |
5ZVT | | STRUCTURE OF RNA POLYMERASE COMPLEX AND GENOME WITHIN A DSRNA VIRUS PROVIDES INSIGHTS INTO THE MECHANISMS OF TRANSCRIPTION AND ASSEMBLY | | Descriptor: | Outer capsid VP7, N-terminus of outer capsid protein VP5, C-terminus of outer capsid protein VP5, ... | | Authors: | Liu, H., Fang, Q., Cheng, L. | | Deposit date: | 2018-05-12 | | Release date: | 2018-07-04 | | Last modified: | 2018-07-25 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5E5A | | CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE | | Descriptor: | DNA (146-MER), Histone H3.2, Histone H4, ... | | Authors: | Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M. | | Deposit date: | 2015-10-08 | | Release date: | 2016-02-03 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.809 Å) | | Cite: | Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
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4PH4 | | THE CRYSTAL STRUCTURE OF HUMAN VPS34 IN COMPLEX WITH PIK-III | | Descriptor: | Phosphatidylinositol 3-kinase catalytic subunit type 3, GLYCEROL, 4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine | | Authors: | Knapp, M.S., Elling, R.A. | | Deposit date: | 2014-05-04 | | Release date: | 2014-10-29 | | Last modified: | 2015-02-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat.Cell Biol., 16, 2014
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4PSW | | CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX | | Descriptor: | Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4 type VIII, ... | | Authors: | Yang, M., Li, Y. | | Deposit date: | 2014-03-08 | | Release date: | 2014-07-09 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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4PSX | | CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX | | Descriptor: | Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4, ... | | Authors: | Yang, M., Li, Y. | | Deposit date: | 2014-03-08 | | Release date: | 2014-07-09 | | Method: | X-RAY DIFFRACTION (2.509 Å) | | Cite: | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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4KUD | | CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED SIR3 BAH DOMAIN D205N MUTANT IN COMPLEX WITH YEAST NUCLEOSOME CORE PARTICLE | | Descriptor: | Histone H3, Histone H4, Histone H2A.2, ... | | Authors: | Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M. | | Deposit date: | 2013-05-22 | | Release date: | 2013-08-07 | | Last modified: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (3.203 Å) | | Cite: | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
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4KUI | | CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN | | Descriptor: | Regulatory protein SIR3, ISOPROPYL ALCOHOL, ACETIC ACID | | Authors: | Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M. | | Deposit date: | 2013-05-22 | | Release date: | 2013-08-07 | | Last modified: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
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4KUL | | CRYSTAL STRUCTURE OF N-TERMINAL ACETYLATED YEAST SIR3 BAH DOMAIN V83P MUTANT | | Descriptor: | Regulatory protein SIR3 | | Authors: | Yang, D., Fang, Q., Wang, M., Ren, R., Wang, H., He, M., Sun, Y., Yang, N., Xu, R.M. | | Deposit date: | 2013-05-22 | | Release date: | 2013-08-07 | | Last modified: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain
Nat.Struct.Mol.Biol., 2013
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3IYL | | ATOMIC CRYOEM STRUCTURE OF A NONENVELOPED VIRUS SUGGESTS HOW MEMBRANE PENETRATION PROTEIN IS PRIMED FOR CELL ENTRY | | Descriptor: | Outer capsid VP4, Core protein VP6, VP1, ... | | Authors: | Zhang, X., Jin, L., Fang, Q., Hui, W., Zhou, Z.H. | | Deposit date: | 2010-02-02 | | Release date: | 2010-05-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | 3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.
Cell(Cambridge,Mass.), 141, 2010
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3K1Q | | BACKBONE MODEL OF AN AQUAREOVIRUS VIRION BY CRYO-ELECTRON MICROSCOPY AND BIOINFORMATICS | | Descriptor: | VP1, VP3A, VP3B, ... | | Authors: | Cheng, L.P., Zhu, J., Hiu, W.H., Zhang, X.K., Honig, B., Fang, Q., Zhou, Z.H. | | Deposit date: | 2009-09-28 | | Release date: | 2010-03-23 | | Last modified: | 2015-01-14 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Backbone Model of an Aquareovirus Virion by Cryo-Electron Microscopy and Bioinformatics
J.Mol.Biol., 397, 2010
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3EP3 | | HUMAN ADOMETDC D174N MUTANT WITH NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EP4 | | HUMAN ADOMETDC E256Q MUTANT WITH NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EP5 | | HUMAN ADOMETDC E178Q MUTANT WITH NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EP6 | | HUMAN ADOMETDC D174N MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EP7 | | HUMAN ADOMETDC E256Q MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EP8 | | HUMAN ADOMETDC E178Q MUTANT COMPLEXED WITH S-ADENOSYLMETHIONINE METHYL ESTER AND NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EP9 | | HUMAN ADOMETDC WITH NO PUTRESCINE BOUND | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, PYRUVIC ACID, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EPA | | HUMAN ADOMETDC E178Q MUTANT COMPLEXED WITH PUTRESCINE | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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3EPB | | HUMAN ADOMETDC E256Q MUTANT COMPLEXED WITH PUTRESCINE | | Descriptor: | S-adenosylmethionine decarboxylase beta chain, S-adenosylmethionine decarboxylase alpha chain, 1,4-DIAMINOBUTANE, ... | | Authors: | Bale, S., Lopez, M.M., Makhatadze, G.I., Fang, Q., Pegg, A.E., Ealick, S.E. | | Deposit date: | 2008-09-29 | | Release date: | 2008-12-23 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
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