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2CE0
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STRUCTURE OF OXIDIZED ARABIDOPSIS THALIANA CYTOCHROME 6A
Descriptor:CYTOCHROME C6, HEME C
Authors:Marcaida, M.J., Schlarb-Ridley, B.G., Worrall, J.A.R., Wastl, J., Evans, T.J., Bendall, D.S., Luisi, B.F., Howe, C.J.
Deposit date:2006-02-01
Release date:2006-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
2CE1
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STRUCTURE OF REDUCED ARABIDOPSIS THALIANA CYTOCHROME 6A
Descriptor:CYTOCHROME C6, HEME C
Authors:Marcaida, M.J., Schlarb-Ridley, B.G., Worrall, J.A.R., Wastl, J., Evans, T.J., Bendall, D.S., Luisi, B.F., Howe, C.J.
Deposit date:2006-02-02
Release date:2006-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
2YIS
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TRIAZOLOPYRIDINE INHIBITORS OF P38 KINASE.
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE 14, 1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
Authors:Millan, D.S., Anderson, M., Bazin, R., Bunnage, M.E., Burrows, J.L., Butcher, K.J., Dodd, P.G., Evans, T.J., Fairman, D.A., Hughes, S.J., Irving, S.L., Kilty, I.C., Lemaitre, A., Lewthwaite, R.A., Mahnke, A., Mathais, J.P., Philip, J., Phillips, C., Smith, R.T., Stefaniack, M.H., Yeadon, M.
Deposit date:2011-05-16
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
2YIW
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TRIAZOLOPYRIDINE INHIBITORS OF P38 KINASE
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE 14, 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
Authors:Millan, D.S., Anderson, M., Bunnage, M.E., Burrows, J.L., Butcher, K.J., Dodd, P.G., Evans, T.J., Fairman, D.A., Hughes, S.J., Irving, S.L., Kilty, I.C., Lemaitre, A., Lewthwaite, R.A., Mahnke, A., Mathais, J.P., Philip, J., Phillips, C., Smith, R.T., Stefamiak, M.H., Yeadon, M.
Deposit date:2011-05-17
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
2YIX
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TRIAZOLOPYRIDINE INHIBITORS OF P38
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE 14, 1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea
Authors:Millan, D.S., Anderson, M., Bunnage, M.E., Burrows, J.L., Butcher, K.J., Dodd, P.G., Evans, T.J., Fairman, D.A., Han, s., Hughes, S.J., Irving, S.L., Kilty, I.C., Lemaitre, A., Lewthawaite, R.A., Mahke, A., Marr, E., Mathias, J.P., Philip, J., Phillips, C., Smith, R.T., Stefaniak, M.H., Yeadon, M.
Deposit date:2011-05-17
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
4F3V
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF ECCA1 ATPASE FROM ESX-1 SECRETION SYSTEM OF MYCOBACTERIUM TUBERCULOSIS
Descriptor:ESX-1 secretion system protein EccA1, SAMARIUM (III) ION, SULFATE ION
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2012-05-09
Release date:2012-06-06
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the N-terminal domain of EccA1 ATPase from the ESX-1 secretion system of Mycobacterium tuberculosis.
Proteins, 82, 2014
4FTF
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STRUCTURE OF THE TYPE II SECRETION SYSTEM PILOTIN ASPS FROM VIBRIO CHOLERAE
Descriptor:Alternate secretin pathway subunit S (VC395_1821, VC1703), ZINC ION, ...
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2012-06-27
Release date:2012-11-28
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS.
Plos Pathog., 9, 2013
4HVL
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STRUCTURE OF A SERINE PROTEASE MYCP1, AN ESSENTIAL COMPONENT OF THE TYPE VII (ESX-1) SECRETION SYSTEM
Descriptor:Membrane-anchored mycosin mycp1, ZINC ION, IMIDAZOLE, ...
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2012-11-06
Release date:2013-05-08
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
4KG7
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STRUCTURE OF MYCP3 PROTEASE FROM THE TYPE VII (ESX-3) SECRETION SYSTEM.
Descriptor:Peptidase S8 and S53, subtilisin, kexin, ...
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2013-04-28
Release date:2013-06-19
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
4KK7
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STRUCTURE OF ECCB1 FROM THE TYPE VII (ESX-1) SECRETION SYSTEM OF MYCOBACTERIUM TUBERCULOSIS.
Descriptor:ESX-1 secretion system protein eccB1, NICKEL (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2013-05-05
Release date:2013-06-19
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
4KV2
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UBIQUITIN-LIKE DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS TYPE VII SECRETION SYSTEM PROTEIN ECCD1
Descriptor:ESX-1 secretion system protein eccD1
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2013-05-22
Release date:2014-04-09
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
4KV3
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UBIQUITIN-LIKE DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS TYPE VII SECRETION SYSTEM PROTEIN ECCD1 AS MALTOSE-BINDING PROTEIN FUSION
Descriptor:Chimera fusion protein of ESX-1 secretion system protein eccD1 and Maltose-binding periplasmic protein, MALTOSE
Authors:Korotkov, K.V., Evans, T.J.
Deposit date:2013-05-22
Release date:2014-04-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
4KXR
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STRUCTURE OF THE MYCOBACTERIUM TUBERCULOSIS TYPE VII SECRETION SYSTEM CHAPERONE ESPG5 IN COMPLEX WITH PE25-PPE41 DIMER
Descriptor:PE25, PPE41, EspG5
Authors:Korotkova, N., Creekmore, C.C., Korotkov, K.V.
Deposit date:2013-05-27
Release date:2014-05-28
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer.
Mol.Microbiol., 94, 2014
4L4W
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STRUCTURE OF ESPG3 CHAPERONE FROM THE TYPE VII (ESX-3) SECRETION SYSTEM
Descriptor:EspG3
Authors:Korotkov, K.V.
Deposit date:2013-06-09
Release date:2014-06-11
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4RCL
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STRUCTURE OF ESPG3 CHAPERONE FROM THE TYPE VII (ESX-3) SECRETION SYSTEM, SPACE GROUP P43212
Descriptor:ESPG3
Authors:Korotkov, K.V.
Deposit date:2014-09-16
Release date:2015-09-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4XWP
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STRUCTURE OF PE-PPE DOMAINS OF ESX-1 SECRETED PROTEIN ESPB, C2221 IN PRESENCE OF CA
Descriptor:ESX-1 secretion-associated protein EspB, CALCIUM ION
Authors:Korotkov, K.V.
Deposit date:2015-01-28
Release date:2015-02-18
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XXN
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STRUCTURE OF PE-PPE DOMAINS OF ESX-1 SECRETED PROTEIN ESPB, I222
Descriptor:ESX-1 secretion-associated protein EspB, CHLORIDE ION, SODIUM ION
Authors:Korotkov, K.V.
Deposit date:2015-01-30
Release date:2015-02-18
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XXX
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STRUCTURE OF PE-PPE DOMAINS OF ESX-1 SECRETED PROTEIN ESPB, C2221
Descriptor:ESX-1 secretion-associated protein EspB, CHLORIDE ION, GLYCEROL
Authors:Piton, J., Pojer, F., Korotkov, K.V.
Deposit date:2015-01-30
Release date:2015-02-18
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XY3
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STRUCTURE OF ESX-1 SECRETED PROTEIN ESPB
Descriptor:ESX-1 secretion-associated protein EspB
Authors:Wagner, J.M., Korotkov, K.V.
Deposit date:2015-02-01
Release date:2015-02-18
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
5CYU
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STRUCTURE OF THE SOLUBLE DOMAIN OF ECCB1 FROM THE MYCOBACTERIUM SMEGMATIS ESX-1 SECRETION SYSTEM.
Descriptor:Conserved membrane protein
Authors:Arbing, M.A., Chan, S., Kahng, S., Kim, J., Eisenberg, D.S., TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-07-30
Release date:2015-08-12
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
5DLB
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CRYSTAL STRUCTURE OF CHAPERONE ESPG3 OF ESX-3 TYPE VII SECRETION SYSTEM FROM MYCOBACTERIUM MARINUM M
Descriptor:chaperone EspG3, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, ...
Authors:Chan, S., Arbing, M.A., Kim, J., Kahng, S., Sawaya, M.R., Eisenberg, D.S., TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-09-04
Release date:2015-09-23
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5SXL
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STRUCTURE OF ESPG3 CHAPERONE FROM THE TYPE VII (ESX-3) SECRETION SYSTEM, SPACE GROUP P3221
Descriptor:ESX-3 secretion-associated protein EspG3
Authors:Korotkov, K.V.
Deposit date:2016-08-09
Release date:2016-08-24
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5VBA
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STRUCTURE OF ESPG1 CHAPERONE FROM THE TYPE VII (ESX-1) SECRETION SYSTEM DETERMINED WITH THE ASSISTANCE OF N-TERMINAL T4 LYSOZYME FUSION
Descriptor:Lysozyme, ESX-1 secretion-associated protein EspG1 chimera, CHLORIDE ION
Authors:Korotkov, K.V.
Deposit date:2017-03-29
Release date:2017-07-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019