1QLP
| 2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS | Descriptor: | ALPHA-1-ANTITRYPSIN | Authors: | Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A. | Deposit date: | 1999-09-10 | Release date: | 1999-09-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci., 9, 2000
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7OWD
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7OWC
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3PV1
| Crystal structure of the USP15 DUSP-UBL domains | Descriptor: | ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | Authors: | Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L. | Deposit date: | 2010-12-06 | Release date: | 2011-11-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural variability of the ubiquitin specific protease DUSP-UBL double domains. Febs Lett., 585, 2011
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5LJM
| Structure of SPATA2 PUB domain | Descriptor: | GLYCEROL, Spermatogenesis-associated protein 2 | Authors: | Elliott, P.R, Komander, D. | Deposit date: | 2016-07-18 | Release date: | 2016-08-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.454 Å) | Cite: | SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. Mol.Cell, 63, 2016
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5LJN
| Structure of the HOIP PUB domain bound to SPATA2 PIM peptide | Descriptor: | E3 ubiquitin-protein ligase RNF31, GLYCEROL, SULFATE ION, ... | Authors: | Elliott, P.R, Komander, D. | Deposit date: | 2016-07-18 | Release date: | 2016-08-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. Mol.Cell, 63, 2016
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3IVF
| Crystal structure of the talin head FERM domain | Descriptor: | Talin-1 | Authors: | Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2009-09-01 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The Structure of the talin head reveals a novel extended conformation of the FERM domain Structure, 18, 2010
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4OYJ
| Structure of the apo HOIP PUB domain | Descriptor: | E3 ubiquitin-protein ligase RNF31, SULFATE ION | Authors: | Elliott, P.R, Komander, D. | Deposit date: | 2014-02-12 | Release date: | 2014-05-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular Basis and Regulation of OTULIN-LUBAC Interaction. Mol.Cell, 54, 2014
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4OYK
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4A3P
| Structure of USP15 DUSP-UBL deletion mutant | Descriptor: | ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | Authors: | Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L. | Deposit date: | 2011-10-03 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. FEBS Lett., 585, 2011
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4A3O
| Crystal structure of the USP15 DUSP-UBL monomer | Descriptor: | GLYCEROL, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | Authors: | Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L. | Deposit date: | 2011-10-03 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. FEBS Lett., 585, 2011
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6SAK
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5OE7
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2LNK
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1PSI
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6I9C
| Structure of the OTU domain of OTULIN G281R mutant | Descriptor: | CHLORIDE ION, GLYCEROL, Ubiquitin thioesterase otulin | Authors: | Damgaard, R.B, Elliott, P.R, Swatek, K.N, Maher, E.R, Stepensky, P, Elpeleg, O, Komander, D, Berkun, Y. | Deposit date: | 2018-11-22 | Release date: | 2019-03-06 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death. Embo Mol Med, 11, 2019
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2KC1
| NMR structure of the F0 domain (residues 0-85) of the talin ferm domain | Descriptor: | MKIAA1027 protein | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2008-12-13 | Release date: | 2010-01-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 29, 2010
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2KMA
| NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain | Descriptor: | Talin 1 | Authors: | Goult, B.T, Elliott, P.R, Bate, N, Roberts, G.C, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2009-07-25 | Release date: | 2010-03-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 2010
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8ATM
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8ATO
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6YIE
| Structure of a Borealin-INCENP-Survivin complex | Descriptor: | Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... | Authors: | Serena, M, Elliott, P.R, Barr, F.A. | Deposit date: | 2020-04-01 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle. J.Cell Biol., 219, 2020
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6YIF
| Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 1.8 A. | Descriptor: | Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... | Authors: | Serena, M, Elliott, P.R, Barr, F.A. | Deposit date: | 2020-04-01 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle. J.Cell Biol., 219, 2020
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6YIH
| Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 2.6 A. | Descriptor: | Baculoviral IAP repeat-containing protein 5, Borealin, Histone H3.1, ... | Authors: | Serena, M, Elliott, P.R, Barr, F.A. | Deposit date: | 2020-04-01 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle. J.Cell Biol., 219, 2020
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6YIP
| Structure of MKLP2 coiled coil | Descriptor: | ISOPROPYL ALCOHOL, Kinesin-like protein KIF20A | Authors: | Serena, M, Elliott, P.R, Barr, F.A. | Deposit date: | 2020-04-01 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle. J.Cell Biol., 219, 2020
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8P5P
| Structure of TECPR1 N-terminal DysF domain | Descriptor: | GLYCEROL, Tectonin beta-propeller repeat-containing protein 1 | Authors: | Boyle, K.B, Elliott, P.R, Randow, F. | Deposit date: | 2023-05-24 | Release date: | 2023-07-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure. Embo J., 42, 2023
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