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1ITG
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BU of 1itg by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES
Descriptor: CACODYLATE ION, HIV-1 INTEGRASE
Authors:Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R.
Deposit date:1994-11-21
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
1PYD
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BU of 1pyd by Molmil
CATALYTIC CENTERS IN THE THIAMIN DIPHOSPHATE DEPENDENT ENZYME PYRUVATE DECARBOXYLASE AT 2.4 ANGSTROMS RESOLUTION
Descriptor: MAGNESIUM ION, PYRUVATE DECARBOXYLASE, THIAMINE DIPHOSPHATE
Authors:Furey, W, Dyda, F.
Deposit date:1993-03-23
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution.
Biochemistry, 32, 1993
6B67
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BU of 6b67 by Molmil
Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA)
Descriptor: CALCIUM ION, Protein phosphatase 1A, cyclic peptide c(MpSIpYVA)
Authors:Dyda, F, Kosek, D.
Deposit date:2017-10-01
Release date:2018-04-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
J. Biol. Chem., 293, 2018
9AZ7
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BU of 9az7 by Molmil
Chloride Sites in Photoactive Yellow Protein
Descriptor: 4'-HYDROXYCINNAMIC ACID, CHLORIDE ION, Photoactive yellow protein
Authors:Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S.
Deposit date:2024-03-10
Release date:2024-03-20
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
9AZ9
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BU of 9az9 by Molmil
Chloride Sites in Photoactive Yellow Protein (Chloride-Free Reference Structure)
Descriptor: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
Authors:Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S.
Deposit date:2024-03-10
Release date:2024-03-20
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
6OPM
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BU of 6opm by Molmil
Casposase bound to integration product
Descriptor: CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ...
Authors:Dyda, F, Hickman, A.B, Kailasan, S.
Deposit date:2019-04-25
Release date:2020-02-12
Last modified:2020-08-26
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Elife, 9, 2020
6DWZ
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BU of 6dwz by Molmil
Hermes transposase deletion dimer complex with (C/G) DNA
Descriptor: DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ...
Authors:Dyda, F, Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DX0
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BU of 6dx0 by Molmil
Hermes transposase deletion dimer complex with (A/T) DNA
Descriptor: DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ...
Authors:Dyda, F, Voth, A.R, Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWY
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BU of 6dwy by Molmil
Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+
Descriptor: CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ...
Authors:Dyda, F, Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWW
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BU of 6dww by Molmil
Hermes transposase deletion dimer complex with (A/T) DNA and Mn2+
Descriptor: DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ...
Authors:Dyda, F, Voth, A.R, Hickman, A.B.
Deposit date:2018-06-28
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
1UUT
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BU of 1uut by Molmil
The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat
Descriptor: 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ...
Authors:Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M.
Deposit date:2004-01-10
Release date:2004-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004
5LME
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BU of 5lme by Molmil
Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase
Descriptor: ZINC ION, piggyBac transposase
Authors:Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E.
Deposit date:2016-07-30
Release date:2017-12-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase.
Nucleic Acids Res., 46, 2018
7TH0
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BU of 7th0 by Molmil
Escherichia coli RpnA-S
Descriptor: Recombination-promoting nuclease RpnA
Authors:Zhong, A, Hickman, A.B, Storz, G, Dyda, F.
Deposit date:2022-01-10
Release date:2023-03-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
2A6O
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BU of 2a6o by Molmil
Crystal Structure of the ISHp608 Transposase in Complex with Stem-loop DNA
Descriptor: 5'-D(*CP*CP*CP*CP*TP*AP*GP*CP*TP*TP*TP*AP*GP*CP*TP*AP*TP*GP*GP*GP*GP*A)-3', ISHp608 Transposase
Authors:Ronning, D.R, Guynet, C, Ton-Hoang, B, Perez, Z.N, Ghirlando, R, Chandler, M, Dyda, F.
Deposit date:2005-07-03
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Active site sharing and subterminal hairpin recognition in a new class of DNA transposases.
Mol.Cell, 20, 2005
2A6M
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BU of 2a6m by Molmil
Crystal Structure of the ISHp608 Transposase
Descriptor: ISHp608 transposase
Authors:Ronning, D.R, Guynet, C, Ton-Hoang, B, Perez, Z.N, Ghirlando, R, Chandler, M, Dyda, F.
Deposit date:2005-07-03
Release date:2005-10-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Active site sharing and subterminal hairpin recognition in a new class of DNA transposases.
Mol.Cell, 20, 2005
8EB5
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BU of 8eb5 by Molmil
Tandem of Hermes transposase BED domain in complex with the quasi palindrome of its transposon left-end
Descriptor: Hermes transposase BED domain, Hermes transposon left-end subterminal repeats 1 and 2, ZINC ION
Authors:Lannes, L, Dyda, F.
Deposit date:2022-08-30
Release date:2023-08-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
8EDG
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BU of 8edg by Molmil
Cryo-EM structure of the Hermes transposase bound to two left-ends of its DNA transposon
Descriptor: DNA (46-MER), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), DNA (55-MER), ...
Authors:Lannes, L, Dyda, F.
Deposit date:2022-09-04
Release date:2023-08-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.64 Å)
Cite:Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
2X2F
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BU of 2x2f by Molmil
Dynamin 1 GTPase dimer, short axis form
Descriptor: DYNAMIN-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chappie, J.S, Acharya, S, Leonard, M, Schmid, S.L, Dyda, F.
Deposit date:2010-01-13
Release date:2010-04-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity.
Nature, 465, 2010
8SJD
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BU of 8sjd by Molmil
Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon.
Descriptor: DNA (46-MER), DNA (55-MER), DNA (8-MER), ...
Authors:Lannes, L, Dyda, F.
Deposit date:2023-04-17
Release date:2023-08-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
2XM3
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BU of 2xm3 by Molmil
Deinococcus radiodurans ISDra2 Transposase Left end DNA complex
Descriptor: 5'-D(*TP*TP*AP*GP*T)-3', ACETATE ION, DRA2 TRANSPOSASE BINDING ELEMENT, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-07-22
Release date:2010-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XQC
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BU of 2xqc by Molmil
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN
Descriptor: 5'-D(TP*TP*GP*AP*TP*GP)-3', DRA2 TRANSPOSASE LEFT END RECOGNITION SEQUENCE, TRANSPOSASE, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-09-01
Release date:2010-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
1T0F
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BU of 1t0f by Molmil
Crystal Structure of the TnsA/TnsC(504-555) complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MALONIC ACID, ...
Authors:Ronning, D.R, Li, Y, Perez, Z.N, Ross, P.D, Hickman, A.B, Craig, N.L, Dyda, F.
Deposit date:2004-04-08
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Embo J., 23, 2004
8T2J
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BU of 8t2j by Molmil
Structure of the catalytic domain of PPM1D/Wip1 serine/threonine phosphatase
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ...
Authors:Kumar, J.P, Kosek, D, Dyda, F.
Deposit date:2023-06-06
Release date:2024-06-12
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain.
J.Biol.Chem., 300, 2024
1RZ9
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BU of 1rz9 by Molmil
Crystal Structure of AAV Rep complexed with the Rep-binding sequence
Descriptor: 26-MER, Rep protein
Authors:Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F.
Deposit date:2003-12-24
Release date:2004-02-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
1YQV
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BU of 1yqv by Molmil
The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution
Descriptor: Hen Egg White Lysozyme, HyHEL-5 Antibody Heavy Chain, HyHEL-5 Antibody Light Chain
Authors:Cohen, G.H, Silverton, E.W, Padlan, E.A, Dyda, F, Wibbenmeyer, J.A, Wilson, R.C, Davies, D.R.
Deposit date:2005-02-02
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Water molecules in the antibody-antigen interface of the structure of the Fab HyHEL-5-lysozyme complex at 1.7 A resolution: comparison with results from isothermal titration calorimetry.
Acta Crystallogr.,Sect.D, 61, 2005

 

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