1YFH
| wt Human O6-Alkylguanine-DNA Alkyltransferase Bound To DNA Containing an Alkylated Cytosine | Descriptor: | 5'-D(*CP*CP*TP*AP*CP*AP*CP*AP*CP*AP*TP*CP*CP*AP*CP*A)-3', 5'-D(*GP*TP*GP*GP*AP*TP*GP*(XCY)P*GP*TP*GP*TP*AP*GP*GP*T)-3', Methylated-DNA--protein-cysteine methyltransferase, ... | Authors: | Duguid, E.M, Rice, P.A, He, C. | Deposit date: | 2004-12-31 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | The structure of the human AGT protein bound to DNA and its implications for damage detection. J.Mol.Biol., 350, 2005
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4I18
| Crystal structure of human prolactin receptor complexed with Fab fragment | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Duguid, E.M, Mukherjee, S, Kouadio, J.L. | Deposit date: | 2012-11-20 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.238 Å) | Cite: | Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling. Cell Commun Signal, 13, 2015
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2BV6
| Crystal structure of MgrA, a global regulator and major virulence determinant in Staphylococcus aureus | Descriptor: | HTH-TYPE TRANSCRIPTIONAL REGULATOR MGRA, SULFATE ION | Authors: | Chen, P.R, Bae, T, Williams, W.A, Duguid, E.M, Rice, P.A, Schneewind, O, He, C. | Deposit date: | 2005-06-22 | Release date: | 2006-09-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An Oxidation-Sensing Mechanism is Used by the Global Regulator Mgra in Staphylococcus Aureus. Nat.Chem.Biol., 2, 2006
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3IVK
| Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment | Descriptor: | CADMIUM ION, CHLORIDE ION, Fab heavy chain, ... | Authors: | Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A. | Deposit date: | 2009-09-01 | Release date: | 2010-03-02 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science, 326, 2009
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3ORS
| Crystal Structure of N5-Carboxyaminoimidazole Ribonucleotide Mutase from Staphylococcus aureus | Descriptor: | N5-Carboxyaminoimidazole Ribonucleotide Mutase, SULFATE ION | Authors: | Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. | Deposit date: | 2010-09-07 | Release date: | 2011-07-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
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3ORQ
| Crystal Structure of N5-Carboxyaminoimidazole synthetase from Staphylococcus aureus complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. | Deposit date: | 2010-09-07 | Release date: | 2011-07-20 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
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3Q5F
| Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*CP*TP*TP*AP*GP*CP*AP*AP*GP*CP*TP*AP*AP*TP*TP*AP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*TP*AP*AP*TP*TP*AP*GP*CP*TP*TP*GP*CP*TP*AP*AP*GP*TP*TP*AP*T)-3'), Transcriptional regulator slyA | Authors: | Dolan, K.T, Duguid, E.M. | Deposit date: | 2010-12-28 | Release date: | 2011-05-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Crystal Structures of SlyA Protein, a Master Virulence Regulator of Salmonella, in Free and DNA-bound States. J.Biol.Chem., 286, 2011
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3ORR
| Crystal Structure of N5-Carboxyaminoimidazole synthetase from Staphylococcus aureus | Descriptor: | N5-carboxyaminoimidazole ribonucleotide synthetase | Authors: | Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. | Deposit date: | 2010-09-07 | Release date: | 2011-07-20 | Last modified: | 2013-04-24 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
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3PGF
| Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB) | Descriptor: | GLYCEROL, IMIDAZOLE, Maltose-binding periplasmic protein, ... | Authors: | Kossiakoff, A.A, Duguid, E.M, Sandstrom, A. | Deposit date: | 2010-11-01 | Release date: | 2011-03-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins. Nat.Struct.Mol.Biol., 18, 2011
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3QPT
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3BKZ
| X-ray structure of E coli AlkB crosslinked to dsDNA in the active site | Descriptor: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB, DNA (5'-D(*DAP*DAP*DCP*DGP*DAP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DT)-3'), ... | Authors: | Yi, C, Yang, C.-G, He, C. | Deposit date: | 2007-12-09 | Release date: | 2008-04-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA Nature, 452, 2008
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3BU0
| crystal structure of human ABH2 cross-linked to dsDNA with cofactors | Descriptor: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*TP*GP*CP*G)-3'), ... | Authors: | Yang, C.-G, Yi, C, He, C. | Deposit date: | 2007-12-31 | Release date: | 2008-04-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature, 452, 2008
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3BTX
| X-ray structure of human ABH2 bound to dsDNA through active site cross-linking | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*TP*GP*CP*G)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DCP*DA)-3'), ... | Authors: | Yang, C.-G, Yi, C, He, C. | Deposit date: | 2007-12-31 | Release date: | 2008-04-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature, 452, 2008
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3BI3
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3BIE
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3BTY
| Crystal structure of human ABH2 bound to dsDNA containing 1meA through cross-linking away from active site | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DGP*DTP*DTP*DAP*DTP*DAP*DCP*DA)-3'), ... | Authors: | Yang, C.-G, Yi, C, He, C. | Deposit date: | 2007-12-31 | Release date: | 2008-04-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature, 452, 2008
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3BTZ
| Crystal structure of human ABH2 cross-linked to dsDNA | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*AP*GP*GP*TP*GP*AP*(2YR)P*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DTP*DTP*DAP*DTP*DCP*DAP*DCP*DC)-3') | Authors: | Yang, C.-G, Yi, C, He, C. | Deposit date: | 2007-12-31 | Release date: | 2008-04-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature, 452, 2008
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3BUC
| X-ray structure of human ABH2 bound to dsDNA with Mn(II) and 2KG | Descriptor: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3'), ... | Authors: | Yang, C.-G, Yi, C, He, C. | Deposit date: | 2008-01-02 | Release date: | 2008-04-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature, 452, 2008
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