Author results

6QDX
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STRUCTURE OF E.COLI RLMJ IN COMPLEX WITH A BISUBSTRATE ANALOGUE (BA4)
Descriptor:Ribosomal RNA large subunit methyltransferase J, (2~{S})-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[[9-[(2~{S},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]propyl]amino]-2-azanyl-butanoic acid
Authors:Oerum, S., Catala, M., Atdjian, C., Brachet, F., Ponchon, L., Barraud, P., Iannazzo, L., Droogmans, L., Braud, E., Etheve-Quelquejeu, M., Tisne, C.
Deposit date:2019-01-03
Release date:2019-03-27
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
6QE0
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STRUCTURE OF E.COLI RLMJ IN COMPLEX WITH A BISUBSTRATE ANALOGUE (BA2)
Descriptor:Ribosomal RNA large subunit methyltransferase J, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic acid
Authors:Oerum, S., Catala, M., Atdjian, C., Brachet, F., Ponchon, L., Barraud, P., Iannazzo, L., Droogmans, L., Braud, E., Etheve-Quelquejeu, M., Tisne, C.
Deposit date:2019-01-03
Release date:2019-03-27
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.394 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
6QE5
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STRUCTURE OF E.COLI RLMJ IN COMPLEX WITH THE NATURAL COFACTOR PRODUCT S-ADENOSYL-HOMOCYSTEINE (SAH)
Descriptor:Ribosomal RNA large subunit methyltransferase J, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Oerum, S., Catala, M., Atdjian, C., Brachet, F., Ponchon, L., Barraud, P., Iannazzo, L., Droogmans, L., Braud, E., Etheve-Quelquejeu, M., Tisne, C.
Deposit date:2019-01-04
Release date:2019-03-27
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
6QE6
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STRUCTURE OF M. CAPRICOLUM TRMK IN COMPLEX WITH THE NATURAL COFACTOR PRODUCT S-ADENOSYL-HOMOCYSTEINE (SAH)
Descriptor:tRNA (Adenine(22)-N(1))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Oerum, S., Catala, M., Atdjian, C., Brachet, F., Ponchon, L., Barraud, P., Iannazzo, L., Droogmans, L., Braud, E., Etheve-Quelquejeu, M., Tisne, C.
Deposit date:2019-01-04
Release date:2019-03-27
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
5A7T
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CRYSTAL STRUCTURE OF SULFOLOBUS ACIDOCALDARIUS TRM10 AT 2.4 ANGSTROM RESOLUTION.
Descriptor:TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE, DI(HYDROXYETHYL)ETHER
Authors:Van Laer, B., Roovers, M., Wauters, L., Kasprzak, J., Dyzma, M., Deyaert, E., Feller, A., Bujnicki, J., Droogmans, L., Versees, W.
Deposit date:2015-07-09
Release date:2016-01-13
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5A7Y
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CRYSTAL STRUCTURE OF SULFOLOBUS ACIDOCALDARIUS TRM10 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE
Descriptor:TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, DI(HYDROXYETHYL)ETHER, ...
Authors:Van Laer, B., Roovers, M., Wauters, L., Kasprzak, J., Dyzma, M., Deyaert, E., Feller, A., Bujnicki, J., Droogmans, L., Versees, W.
Deposit date:2015-07-10
Release date:2016-01-13
Last modified:2016-02-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5A7Z
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CRYSTAL STRUCTURE OF SULFOLOBUS ACIDOCALDARIUS TRM10 AT 2.1 ANGSTROM RESOLUTION.
Descriptor:TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE
Authors:Van Laer, B., Roovers, M., Wauters, L., Kasprzak, J., Dyzma, M., Deyaert, E., Feller, A., Bujnicki, J., Droogmans, L., Versees, W.
Deposit date:2015-07-10
Release date:2016-01-13
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
1HX3
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CRYSTAL STRUCTURE OF E.COLI ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
Descriptor:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, SULFATE ION, MANGANESE (II) ION, ...
Authors:Durbecq, V., Sainz, G., Oudjama, Y., Clantin, B., Bompard-Gilles, C., Tricot, C., Caillet, J., Stalon, V., Droogmans, L., Villeret, V.
Deposit date:2001-01-11
Release date:2001-07-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
1HZT
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CRYSTAL STRUCTURE OF METAL-FREE ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
Descriptor:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE
Authors:Durbecq, V., Sainz, G., Oudjama, Y., Clantin, B., Bompard-Gilles, C., Tricot, C., Caillet, J., Stalon, V., Droogmans, L., Villeret, V.
Deposit date:2001-01-26
Release date:2001-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
1PVF
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E.COLI IPP ISOMERASE IN COMPLEX WITH DIPHOSPHATE
Descriptor:Isopentenyl-diphosphate delta-isomerase, MANGANESE (II) ION, MAGNESIUM ION, ...
Authors:Wouters, J., Durisotti, V., Oudjama, Y., Stalon, V., Droogmans, L.
Deposit date:2003-06-27
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:E.coli Isopentenyl Diphosphate: Dimethylallyl Diphosphate isomerase in complex with diphosphate
To be Published
1Q54
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STRUCTURE AND MECHANISM OF ACTION OF ISOPENTENYLPYROPHOSPHATE-DIMETHYLALLYLPYROPHOSPHATE ISOMERASE: COMPLEX WITH THE BROMOHYDRINE OF IPP
Descriptor:ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, MANGANESE (II) ION, MAGNESIUM ION, ...
Authors:Wouters, J., Oudjama, Y., Ghosh, S., Stalon, V., Droogmans, L.
Deposit date:2003-08-06
Release date:2003-08-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase.
J.Am.Chem.Soc., 125, 2003
2FCA
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THE STRUCTURE OF BSTRMB
Descriptor:tRNA (guanine-N(7)-)-methyltransferase, POTASSIUM ION
Authors:Zegers, I., Van Vliet, F., Bujnicki, J., Kosinski, J., Gigot, D., Droogmans, L.
Deposit date:2005-12-12
Release date:2006-08-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Nucleic Acids Res., 34, 2006
3TLJ
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CRYSTAL STRUCTURE OF TRM14 FROM PYROCOCCUS FURIOSUS IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:tRNA (guanine N2-)-methyltransferase Trm14, S-ADENOSYL-L-HOMOCYSTEINE, ACETATE ION
Authors:Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.
Deposit date:2011-08-30
Release date:2012-03-14
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3TM4
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CRYSTAL STRUCTURE OF TRM14 FROM PYROCOCCUS FURIOSUS IN COMPLEX WITH S-ADENOSYLMETHIONINE
Descriptor:tRNA (guanine N2-)-methyltransferase Trm14, S-ADENOSYLMETHIONINE
Authors:Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.
Deposit date:2011-08-31
Release date:2012-03-14
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3TM5
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CRYSTAL STRUCTURE OF TRM14 FROM PYROCOCCUS FURIOSUS IN COMPLEX WITH SINEFUNGIN
Descriptor:Crystal structure of Trm14, SINEFUNGIN
Authors:Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.
Deposit date:2011-08-31
Release date:2012-03-14
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3TMA
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CRYSTAL STRUCTURE OF TRMN FROM THERMUS THERMOPHILUS
Descriptor:methyltransferase, PHOSPHATE ION
Authors:Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.
Deposit date:2011-08-31
Release date:2012-03-14
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
4CND
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CRYSTAL STRUCTURE OF E.COLI TRMJ
Descriptor:TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ, DI(HYDROXYETHYL)ETHER
Authors:Van Laer, B., Somme, J., Roovers, M., Steyaert, J., Droogmans, L., Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNE
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CRYSTAL STRUCTURE OF E.COLI TRMJ IN COMPLEX WITH S-ADENOSYL-L- HOMOCYSTEINE
Descriptor:TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ, S-ADENOSYL-L-HOMOCYSTEINE, DI(HYDROXYETHYL)ETHER
Authors:Van Laer, B., Somme, J., Roovers, M., Steyaert, J., Droogmans, L., Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNF
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CRYSTAL STRUCTURE OF SULFOLOBUS ACIDOCALDARIUS TRMJ
Descriptor:SPOU RRNA METHYLASE, GLYCEROL, DI(HYDROXYETHYL)ETHER, ...
Authors:Van Laer, B., Somme, J., Roovers, M., Steyaert, J., Droogmans, L., Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNG
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CRYSTAL STRUCTURE OF SULFOLOBUS ACIDOCALDARIUS TRMJ IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:SPOU RRNA METHYLASE, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL
Authors:Van Laer, B., Somme, J., Roovers, M., Steyaert, J., Droogmans, L., Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
6Q56
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CRYSTAL STRUCTURE OF THE B. SUBTILIS M1A22 TRNA METHYLTRANSFERASE TRMK
Descriptor:tRNA (adenine(22)-N(1))-methyltransferase, NICKEL (II) ION
Authors:Degut, C., Roovers, M., Barraud, P., Brachet, F., Feller, A., Larue, V., Al Refaii, A., Caillet, J., Droogmans, L., Tisne, C.
Deposit date:2018-12-07
Release date:2019-03-27
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Nucleic Acids Res., 47, 2019
6EMS
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CRYSTAL STRUCTURE OF DUAL SPECIFIC TRM10 CONSTRUCT FROM THERMOCOCCUS KODAKARAENSIS.
Descriptor:tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase
Authors:Singh, R.K., Versees, W.
Deposit date:2017-10-03
Release date:2018-06-13
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018
6EMT
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CRYSTAL STRUCTURE OF DUAL SPECIFIC TRM10 CONSTRUCT FROM THERMOCOCCUS KODAKARAENSIS.
Descriptor:tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase, ACETATE ION, GLYCEROL, ...
Authors:Singh, R.K., Versees, W.
Deposit date:2017-10-03
Release date:2018-06-13
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018
6EMU
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CRYSTAL STRUCTURE OF DUAL SPECIFIC TRM10 CONSTRUCT FROM THERMOCOCCUS KODAKARAENSIS.
Descriptor:tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase, S-ADENOSYLMETHIONINE, GLYCEROL
Authors:Singh, R.K., Versees, W.
Deposit date:2017-10-03
Release date:2018-06-13
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.297454 Å)
Cite:Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018
6EMV
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CRYSTAL STRUCTURE OF DUAL SPECIFIC TRM10 CONSTRUCT FROM THERMOCOCCUS KODAKARAENSIS.
Descriptor:tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Singh, R.K., Versees, W.
Deposit date:2017-10-03
Release date:2018-06-13
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.900014 Å)
Cite:Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018
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