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2FCA
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BU of 2fca by Molmil
The structure of BsTrmB
Descriptor: POTASSIUM ION, tRNA (guanine-N(7)-)-methyltransferase
Authors:Zegers, I, Van Vliet, F, Bujnicki, J, Kosinski, J, Gigot, D, Droogmans, L.
Deposit date:2005-12-12
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Nucleic Acids Res., 34, 2006
7QIU
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BU of 7qiu by Molmil
YsgA 23s RNA methyltransferase from Bacillus subtilis
Descriptor: rRNA methylase
Authors:Labar, G, Van Elder, D, Roovers, M, Droogmans, L.
Deposit date:2021-12-16
Release date:2022-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.877 Å)
Cite:The Bacillus subtilis open reading frame ysgA encodes the SPOUT methyltransferase RlmP forming 2'- O -methylguanosine at position 2553 in the A-loop of 23S rRNA.
Rna, 28, 2022
6Q56
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BU of 6q56 by Molmil
Crystal structure of the B. subtilis M1A22 tRNA methyltransferase TrmK
Descriptor: NICKEL (II) ION, tRNA (adenine(22)-N(1))-methyltransferase
Authors:Degut, C, Roovers, M, Barraud, P, Brachet, F, Feller, A, Larue, V, Al Refaii, A, Caillet, J, Droogmans, L, Tisne, C.
Deposit date:2018-12-07
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Nucleic Acids Res., 47, 2019
6QE6
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BU of 6qe6 by Molmil
Structure of M. capricolum TrmK in complex with the natural cofactor product S-adenosyl-homocysteine (SAH)
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Adenine(22)-N(1))-methyltransferase
Authors:Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C.
Deposit date:2019-01-04
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
6QE5
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BU of 6qe5 by Molmil
Structure of E.coli RlmJ in complex with the natural cofactor product S-adenosyl-homocysteine (SAH)
Descriptor: Ribosomal RNA large subunit methyltransferase J, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C.
Deposit date:2019-01-04
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
6QDX
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BU of 6qdx by Molmil
Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA4)
Descriptor: (2~{S})-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[[9-[(2~{S},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]propyl]amino]-2-azanyl-butanoic acid, Ribosomal RNA large subunit methyltransferase J
Authors:Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C.
Deposit date:2019-01-03
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
6QE0
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BU of 6qe0 by Molmil
Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA2)
Descriptor: (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic acid, Ribosomal RNA large subunit methyltransferase J
Authors:Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C.
Deposit date:2019-01-03
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.394 Å)
Cite:Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol., 16, 2019
3TMA
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BU of 3tma by Molmil
Crystal structure of TrmN from Thermus thermophilus
Descriptor: PHOSPHATE ION, methyltransferase
Authors:Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
Deposit date:2011-08-31
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
5A7T
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BU of 5a7t by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 at 2.4 angstrom resolution.
Descriptor: DI(HYDROXYETHYL)ETHER, TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE
Authors:Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
Deposit date:2015-07-09
Release date:2016-01-13
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5A7Y
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BU of 5a7y by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 in complex with S-adenosylhomocysteine
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
Deposit date:2015-07-10
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5A7Z
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BU of 5a7z by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 at 2.1 angstrom resolution.
Descriptor: TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE
Authors:Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
Deposit date:2015-07-10
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
1HX3
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BU of 1hx3 by Molmil
CRYSTAL STRUCTURE OF E.COLI ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
Descriptor: IMIDAZOLE, ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, MANGANESE (II) ION, ...
Authors:Durbecq, V, Sainz, G, Oudjama, Y, Clantin, B, Bompard-Gilles, C, Tricot, C, Caillet, J, Stalon, V, Droogmans, L, Villeret, V.
Deposit date:2001-01-11
Release date:2001-07-11
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
1HZT
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BU of 1hzt by Molmil
CRYSTAL STRUCTURE OF METAL-FREE ISOPENTENYL DIPHOSPHATE:DIMETHYLALLYL DIPHOSPHATE ISOMERASE
Descriptor: ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE
Authors:Durbecq, V, Sainz, G, Oudjama, Y, Clantin, B, Bompard-Gilles, C, Tricot, C, Caillet, J, Stalon, V, Droogmans, L, Villeret, V.
Deposit date:2001-01-26
Release date:2001-07-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
Embo J., 20, 2001
3TM4
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BU of 3tm4 by Molmil
Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosylmethionine
Descriptor: S-ADENOSYLMETHIONINE, tRNA (guanine N2-)-methyltransferase Trm14
Authors:Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
Deposit date:2011-08-31
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3TLJ
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BU of 3tlj by Molmil
Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine
Descriptor: ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine N2-)-methyltransferase Trm14
Authors:Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
Deposit date:2011-08-30
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3TM5
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BU of 3tm5 by Molmil
Crystal structure of Trm14 from Pyrococcus furiosus in complex with sinefungin
Descriptor: Crystal structure of Trm14, SINEFUNGIN
Authors:Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
Deposit date:2011-08-31
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
1Q54
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BU of 1q54 by Molmil
STRUCTURE AND MECHANISM OF ACTION OF ISOPENTENYLPYROPHOSPHATE-DIMETHYLALLYLPYROPHOSPHATE ISOMERASE: COMPLEX WITH THE BROMOHYDRINE OF IPP
Descriptor: 4-BROMO-3-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, MAGNESIUM ION, ...
Authors:Wouters, J, Oudjama, Y, Ghosh, S, Stalon, V, Droogmans, L.
Deposit date:2003-08-06
Release date:2003-08-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase.
J.Am.Chem.Soc., 125, 2003
1PVF
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BU of 1pvf by Molmil
E.coli IPP isomerase in complex with diphosphate
Descriptor: DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ...
Authors:Wouters, J, Durisotti, V, Oudjama, Y, Stalon, V, Droogmans, L.
Deposit date:2003-06-27
Release date:2004-07-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:E.coli Isopentenyl Diphosphate: Dimethylallyl Diphosphate isomerase in complex with diphosphate
To be Published
4CNE
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BU of 4cne by Molmil
Crystal structure of E.coli TrmJ in complex with S-adenosyl-L- homocysteine
Descriptor: DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
Authors:Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNF
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BU of 4cnf by Molmil
Crystal structure of Sulfolobus acidocaldarius TrmJ
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNG
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BU of 4cng by Molmil
Crystal structure of Sulfolobus acidocaldarius TrmJ in complex with S-adenosyl-L-Homocysteine
Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, SPOU RRNA METHYLASE
Authors:Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CND
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BU of 4cnd by Molmil
Crystal structure of E.coli TrmJ
Descriptor: DI(HYDROXYETHYL)ETHER, TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
Authors:Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
Deposit date:2014-01-22
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
5L6Z
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BU of 5l6z by Molmil
Crystal structure of D62A mutant of Thermotoga maritima TmPEP1050 aminopeptidase
Descriptor: CITRIC ACID, SODIUM ION, leucylaminopeptidase
Authors:Dutoit, R, Van Elder, D, Bauvois, C.
Deposit date:2016-06-01
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:M42 aminopeptidase catalytic site: the structural and functional role of a strictly conserved aspartate residue
Proteins, 2020
2PWY
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BU of 2pwy by Molmil
Crystal Structure of a m1A58 tRNA methyltransferase
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, tRNA (adenine-N(1)-)-methyltransferase
Authors:Barraud, P, Golinelli-Pimpaneau, B, Tisne, C.
Deposit date:2007-05-14
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Thermus thermophilus tRNA m(1)A(58) Methyltransferase and Biophysical Characterization of Its Interaction with tRNA.
J.Mol.Biol., 377, 2008
6EMT
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BU of 6emt by Molmil
Crystal Structure of dual specific Trm10 construct from Thermococcus kodakaraensis.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ...
Authors:Singh, R.K, Versees, W.
Deposit date:2017-10-03
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018

 

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