1SLQ
| Crystal structure of the trimeric state of the rhesus rotavirus VP4 membrane interaction domain, VP5CT | Descriptor: | VP4 | Authors: | Dormitzer, P.R, Nason, E.B, Prasad, B.V.V, Harrison, S.C. | Deposit date: | 2004-03-06 | Release date: | 2004-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural rearrangements in the membrane penetration protein of a non-enveloped virus. Nature, 430, 2004
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1KRI
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1KQR
| Crystal Structure of the Rhesus Rotavirus VP4 Sialic Acid Binding Domain in Complex with 2-O-methyl-alpha-D-N-acetyl neuraminic acid | Descriptor: | 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, GLYCEROL, SULFATE ION, ... | Authors: | Dormitzer, P.R, Sun, Z.-Y.J, Wagner, G, Harrison, S.C. | Deposit date: | 2002-01-07 | Release date: | 2002-03-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a
Novel Carbohydrate Binding Site Embo J., 21, 2002
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4V7Q
| Atomic model of an infectious rotavirus particle | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Core scaffold protein, ... | Authors: | Settembre, E.C, Chen, J.Z, Dormitzer, P.R, Grigorieff, N, Harrison, S.C. | Deposit date: | 2010-05-13 | Release date: | 2014-07-09 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic model of an infectious rotavirus particle. Embo J., 30, 2011
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7KDP
| HCMV prefusion gB in complex with fusion inhibitor WAY-174865 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... | Authors: | Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. | Deposit date: | 2020-10-09 | Release date: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion. Sci Adv, 7, 2021
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7KDD
| HCMV postfusion gB in complex with SM5-1 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... | Authors: | Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. | Deposit date: | 2020-10-08 | Release date: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion. Sci Adv, 7, 2021
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2AEN
| Crystal structure of the rotavirus strain DS-1 VP8* core | Descriptor: | ETHANOL, GLYCEROL, Outer capsid protein VP4, ... | Authors: | Monnier, N, Higo-Moriguchi, K, Sun, Z.-Y.J, Prasad, B.V.V, Taniguchi, K, Dormitzer, P.R. | Deposit date: | 2005-07-22 | Release date: | 2006-02-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | High-resolution molecular and antigen structure of the VP8*
core of a sialic acid-independent human rotavirus strain J.Virol., 80, 2006
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2B4I
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2B4H
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3FMG
| Structure of rotavirus outer capsid protein VP7 trimer in complex with a neutralizing Fab | Descriptor: | CALCIUM ION, Fab of neutralizing antibody 4F8, heavy chain, ... | Authors: | Aoki, S.T, Settembre, E.C, Trask, S.D, Greenberg, H.B, Harrison, S.C, Dormitzer, P.R. | Deposit date: | 2008-12-22 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science, 324, 2009
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3RKI
| Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 | Authors: | Swanson, K.A, Settembre, E.C, Shaw, C.A, Dey, A.K, Rappuoli, R, Mandl, C.W, Dormitzer, P.D, Carfi, A. | Deposit date: | 2011-04-18 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers. Proc.Natl.Acad.Sci.USA, 108, 2011
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5IBU
| 6652 Fab (unbound) | Descriptor: | 6652 Heavy Chain, 6652 Light Chain | Authors: | Raymond, D.D, Harrison, S.C. | Deposit date: | 2016-02-22 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nat. Med., 22, 2016
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5UGY
| Influenza hemagglutinin in complex with a neutralizing antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH65 heavy chain, ... | Authors: | Whittle, J.R.R, Jenni, S, Harrison, S.C. | Deposit date: | 2017-01-10 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proc. Natl. Acad. Sci. U.S.A., 108, 2011
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5IBL
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5IBT
| UCA Fab (unbound) from 6515 Lineage | Descriptor: | GLYCEROL, UCA Heavy Chain, UCA Light Chain | Authors: | Raymond, D.D, Harrison, S.C. | Deposit date: | 2016-02-22 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nat. Med., 22, 2016
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7UJA
| Cryo-EM structure of Human respiratory syncytial virus F variant (construct pXCS847A) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab heavy chain, AM14 Fab light chain, ... | Authors: | Lees, J.A, Ammirati, M, Han, S. | Deposit date: | 2022-03-30 | Release date: | 2023-04-19 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine. Sci Transl Med, 15, 2023
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7UJ3
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7L7F
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7L7K
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3GZT
| VP7 recoated rotavirus DLP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Outer capsid glycoprotein VP7 | Authors: | Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N. | Deposit date: | 2009-04-07 | Release date: | 2009-07-14 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM Proc.Natl.Acad.Sci.USA, 106, 2009
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3GZU
| VP7 recoated rotavirus DLP | Descriptor: | Inner capsid protein VP2, Intermediate capsid protein VP6, ZINC ION | Authors: | Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N. | Deposit date: | 2009-04-07 | Release date: | 2009-07-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc.Natl.Acad.Sci.USA, 106, 2009
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4HKB
| CH67 Fab (unbound) from the CH65-67 Lineage | Descriptor: | CH67 heavy chain, CH67 light chain | Authors: | Schmidt, A.G, Harrison, S.C. | Deposit date: | 2012-10-15 | Release date: | 2012-11-21 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HK3
| I2 Fab (unbound) from CH65-CH67 Lineage | Descriptor: | I2 heavy chain, I2 light chain | Authors: | Schmidt, A.G, Harrison, S.C. | Deposit date: | 2012-10-14 | Release date: | 2012-11-21 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HKX
| Influenza hemagglutinin in complex with CH67 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ... | Authors: | Schmidt, A.G, Harrison, S.C. | Deposit date: | 2012-10-15 | Release date: | 2012-11-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HK0
| UCA Fab (unbound) from CH65-CH67 Lineage | Descriptor: | UCA heavy chain, UCA light chain | Authors: | Schmidt, A.G, Harrison, S.C. | Deposit date: | 2012-10-14 | Release date: | 2012-11-21 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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