Author results

1TIB
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CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR
Descriptor:LIPASE
Authors:Derewenda, U., Swenson, L., Wei, Y., Derewenda, Z.S.
Deposit date:1993-12-06
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
J.Lipid Res., 35, 1994
1TIC
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CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR
Descriptor:LIPASE
Authors:Derewenda, U., Swenson, L., Green, R., Joerger, R., Haas, M.J., Derewenda, Z.S.
Deposit date:1993-12-06
Release date:1995-01-26
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
J.Lipid Res., 35, 1994
4TGL
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CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE
Descriptor:TRIACYL-GLYCEROL ACYLHYDROLASE, DIETHYL PHOSPHONATE
Authors:Derewenda, U., Brzozowski, A.M., Lawson, D., Derewenda, Z.S.
Deposit date:1991-07-29
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase.
Biochemistry, 31, 1992
1TIA
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AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES
Descriptor:LIPASE
Authors:Derewenda, U., Swenson, L., Yamaguchi, S., Wei, Y., Derewenda, Z.S.
Deposit date:1993-12-06
Release date:1995-01-26
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An unusual buried polar cluster in a family of fungal lipases.
Nat.Struct.Biol., 1, 1994
1KTJ
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X-RAY STRUCTURE OF DER P 2, THE MAJOR HOUSE DUST MITE ALLERGEN
Descriptor:ALLERGEN DER P 2
Authors:Derewenda, U., Li, J., Derewenda, Z., Dauter, Z., Mueller, G.A., Rule, G.S., Benjamin, D.C.
Deposit date:2002-01-16
Release date:2002-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
1R6F
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THE STRUCTURE OF YERSINIA PESTIS V-ANTIGEN, AN ESSENTIAL VIRULENCE FACTOR AND MEDIATOR OF IMMUNITY AGAINST PLAGUE
Descriptor:Virulence-associated V antigen
Authors:Derewenda, U., Mateja, A., Devedjiev, Y., Routzahn, K.M., Evdokimov, A.G., Derewenda, Z.S., Waugh, D.S.
Deposit date:2003-10-15
Release date:2004-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague
Structure, 12, 2004
1XAS
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CRYSTAL STRUCTURE, AT 2.6 ANGSTROMS RESOLUTION, OF THE STREPTOMYCES LIVIDANS XYLANASE A, A MEMBER OF THE F FAMILY OF BETA-1,4-D-GLYCANSES
Descriptor:1,4-BETA-D-XYLAN XYLANOHYDROLASE
Authors:Derewenda, U., Derewenda, Z.S.
Deposit date:1994-05-31
Release date:1995-05-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure, at 2.6-A resolution, of the Streptomyces lividans xylanase A, a member of the F family of beta-1,4-D-glycanases.
J.Biol.Chem., 269, 1994
1XCG
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CRYSTAL STRUCTURE OF HUMAN RHOA IN COMPLEX WITH DH/PH FRAGMENT OF PDZRHOGEF
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Derewenda, U., Oleksy, A., Stevenson, A.S., Korczynska, J., Dauter, Z., Somlyo, A.P., Otlewski, J., Somlyo, A.V., Derewenda, Z.S.
Deposit date:2004-09-01
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle
Structure, 12, 2004
2V71
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COILED-COIL REGION OF NUDEL
Descriptor:NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1
Authors:Derewenda, U., Cooper, D.R., Kim, M.H., Derewenda, Z.S.
Deposit date:2007-07-25
Release date:2007-11-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly.
Structure, 15, 2007
3FHK
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CRYSTAL STRUCTURE OF APC1446, B.SUBTILIS YPHP DISULFIDE ISOMERASE
Descriptor:UPF0403 protein yphP, SULFATE ION
Authors:Derewenda, U., Boczek, T., Cooper, D.R., Yu, M., Hung, L., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2008-12-09
Release date:2009-09-01
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif .
Biochemistry, 48, 2009
4GUE
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STRUCTURE OF N-TERMINAL KINASE DOMAIN OF RSK2 WITH FLAVONOID GLYCOSIDE QUERCITRIN
Descriptor:Ribosomal protein S6 kinase alpha-3, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, ...
Authors:Derewenda, U., Utepbergenov, D., Szukalska, G., Derewenda, Z.S.
Deposit date:2012-08-29
Release date:2013-01-30
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 69, 2013
6INS
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X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE
Descriptor:INSULIN, ZINC ION
Authors:Derewenda, U., Derewenda, Z., Dodson, E.J., Dodson, G.G., Bing, X., Markussen, J.
Deposit date:1992-11-25
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
J.Mol.Biol., 220, 1991
3QOR
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CRYSTAL STRUCTURE OF HUMAN NUCLEAR MIGRATION PROTEIN NUDC
Descriptor:Nuclear migration protein nudC, ACETATE ION
Authors:Derewenda, U., Derewenda, Z., Zheng, M.
Deposit date:2011-02-10
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.753 Å)
Cite:Structural Features and Chaperone Activity of the NudC Protein Family.
J.Mol.Biol., 409, 2011
4QAZ
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (ZAIRE) NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Derewenda, U., Dziubanska, P.J., Derewenda, Z.S.
Deposit date:2014-05-06
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein.
Acta Crystallogr.,Sect.D, 70, 2014
4QB0
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THE CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF EBOLA (ZAIRE) NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Derewenda, U., Dziubanska, P.J., Derewenda, Z.S.
Deposit date:2014-05-06
Release date:2014-09-10
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein.
Acta Crystallogr.,Sect.D, 70, 2014
5IRC
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P190A GAP DOMAIN COMPLEX WITH RHOA
Descriptor:Rho GTPase-activating protein 35, Transforming protein RhoA, CHLORIDE ION, ...
Authors:Derewenda, U., Derewenda, Z.
Deposit date:2016-03-12
Release date:2016-08-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
1BWP
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWQ
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWR
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1CC0
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CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX
Descriptor:transforming protein rhoA, rho GDP dissociation inhibitor alpha, MAGNESIUM ION, ...
Authors:Longenecker, K.L., Read, P., Derewenda, U., Dauter, Z., Garrard, S., Walker, L., Somlyo, A.V., Somlyo, A.P., Nakamoto, R.K., Derewenda, Z.S.
Deposit date:1999-03-03
Release date:2000-01-07
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (5 Å)
Cite:How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
1E0V
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XYLANASE 10A FROM SREPTOMYCES LIVIDANS. CELLOBIOSYL-ENZYME INTERMEDIATE AT 1.7 A
Descriptor:ENDO-1,4-BETA-XYLANASE A, 2-DEOXY-2-FLUORO-B-D-CELLOBIOSIDE
Authors:Ducros, V., Charnock, S.J., Derewenda, U., Derewenda, Z.S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D., Davies, G.J.
Deposit date:2000-04-10
Release date:2001-04-05
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
1E0W
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XYLANASE 10A FROM SREPTOMYCES LIVIDANS. NATIVE STRUCTURE AT 1.2 ANGSTROM RESOLUTION
Descriptor:ENDO-1,4-BETA-XYLANASE A
Authors:Ducros, V., Charnock, S.J., Derewenda, U., Derewenda, Z.S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D., Davies, G.J.
Deposit date:2000-04-10
Release date:2001-04-05
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
1E0X
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XYLANASE 10A FROM SREPTOMYCES LIVIDANS. XYLOBIOSYL-ENZYME INTERMEDIATE AT 1.65 A
Descriptor:ENDO-1,4-BETA-XYLANASE A, GLYCEROL, 2-DEOXY-2-FLUORO XYLOPYRANOSE, ...
Authors:Ducros, V., Charnock, S.J., Derewenda, U., Derewenda, Z.S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D., Davies, G.J.
Deposit date:2000-04-10
Release date:2001-04-05
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
1ESC
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THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
Descriptor:ESTERASE
Authors:Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.
Deposit date:1994-10-07
Release date:1995-10-15
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
1F7C
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CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE
Descriptor:RHOGAP PROTEIN
Authors:Longenecker, K.L., Derewenda, U., Sheffield, P.J., Zheng, Y., Derewenda, Z.S.
Deposit date:2000-06-26
Release date:2000-12-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the BH domain from graf and its implications for Rho GTPase recognition.
J.Biol.Chem., 275, 2000