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1S36
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CRYSTAL STRUCTURE OF A CA2+-DISCHARGED PHOTOPROTEIN: IMPLICATIONS FOR THE MECHANISMS OF THE CALCIUM TRIGGER AND THE BIOLUMINESCENCE
Descriptor:Obelin, SODIUM ION, CHLORIDE ION, ...
Authors:Deng, L., Markova, S.V., Vysotski, E.S., Liu, Z.-J., Lee, J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-01-12
Release date:2004-10-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of a Ca2+-discharged photoprotein: implications for mechanisms of the calcium trigger and bioluminescence
J.Biol.Chem., 279, 2004
1SL7
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CRYSTAL STRUCTURE OF CALCIUM-LOADED APO-OBELIN FROM OBELIA LONGISSIMA
Descriptor:Obelin, CALCIUM ION
Authors:Deng, L., Markova, S.V., Vysotski, E.S., Liu, Z.J., Lee, J., Rose, J., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-03-05
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Protein Sci., 14, 2005
1SL8
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CALCIUM-LOADED APO-AEQUORIN FROM AEQUOREA VICTORIA
Descriptor:Aequorin 1, CALCIUM ION
Authors:Deng, L., Markova, S.V., Vysotski, E.S., Liu, Z.J., Lee, J., Rose, J., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-03-05
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Protein Sci., 14, 2005
1SL9
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OBELIN FROM OBELIA LONGISSIMA
Descriptor:Obelin, C2-HYDROPEROXY-COELENTERAZINE
Authors:Deng, L., Markova, S., Vysotski, E., Liu, Z.-J., Lee, J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-03-05
Release date:2005-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Obelin from Obelia longissima
To be Published
1JF0
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THE CRYSTAL STRUCTURE OF OBELIN FROM OBELIA GENICULATA AT 1.82 A RESOLUTION
Descriptor:Obelin, C2-HYDROPEROXY-COELENTERAZINE
Authors:Deng, L., Vysotski, E., Liu, Z.-J., Markova, S., Lee, J., Rose, J., Wang, B.-C.
Deposit date:2001-06-19
Release date:2001-07-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of Obelin from Obelia geniculata at 1.82 Angstrom Resolution
To be Published
4HZL
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NEUTRALIZING ANTIBODY MAB#8 IN COMPLEX WITH THE EPITOPE II OF HCV E2 ENVELOPE PROTEIN
Descriptor:Fab heavy chain, Fab light chain, E2 envelop protein
Authors:Deng, L., Zhang, P.
Deposit date:2012-11-15
Release date:2013-05-01
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4Q0X
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CRYSTAL STRUCTURE OF NON-NEUTRALIZING ANTIBODY IN COMPLEX WITH EPITOPE II OF HCV E2
Descriptor:mAb 12 heavy chain, mAb 12 light chain, Envelope glycoprotein E2
Authors:Deng, L., Zhang, P.
Deposit date:2014-04-02
Release date:2014-07-09
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
2IAL
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STRUCTURAL BASIS FOR RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED TCR
Descriptor:CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain
Authors:Deng, L., Langley, R.J., Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAM
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STRUCTURAL BASIS FOR RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED TCR
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L., Langley, R.J., Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAN
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STRUCTURAL BASIS FOR RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED TCR
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L., Langley, R.J., Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
3M18
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CRYSTAL STRUCTURE OF VARIABLE LYMPHOCYTE RECEPTOR VLRA.R2.1 IN COMPLEX WITH HEN EGG LYSOZYME
Descriptor:Variable lymphocyte receptor A diversity region, Lysozyme C, PHOSPHATE ION
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M19
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CRYSTAL STRUCTURE OF VARIABLE LYMPHOCYTE RECEPTOR VLRA.R5.1
Descriptor:Variable lymphocyte receptor A diversity region
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
1PRY
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STRUCTURE DETERMINATION OF FIBRILLARIN HOMOLOGUE FROM HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS FURIOSUS (PFU-65527)
Descriptor:Fibrillarin-like pre-rRNA processing protein
Authors:Deng, L., Starostina, N.G., Liu, Z.-J., Rose, J.P., Terns, R.M., Terns, M.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-06-20
Release date:2004-03-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus
Biochem.Biophys.Res.Commun., 315, 2004
1YWO
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PHOSPHOLIPASE CGAMMA1 SH3 IN COMPLEX WITH A SLP-76 MOTIF
Descriptor:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, Lymphocyte cytosolic protein 2
Authors:Deng, L., Velikovsky, C.A., Swaminathan, C.P., Cho, S., Mariuzza, R.A.
Deposit date:2005-02-18
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
1YWP
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PHOSPHOLIPASE CGAMMA1 SH3
Descriptor:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
Authors:Deng, L., Velikovsky, C.A., Swaminathan, C.P., Cho, S., Mariuzza, R.A.
Deposit date:2005-02-18
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
3C8J
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THE CRYSTAL STRUCTURE OF NATURAL KILLER CELL RECEPTOR LY49C
Descriptor:Natural killer cell receptor Ly49C
Authors:Deng, L., Mariuzza, R.A.
Deposit date:2008-02-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
3C8K
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THE CRYSTAL STRUCTURE OF LY49C BOUND TO H-2KB
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, beta-2 microglobulin, ...
Authors:Deng, L., Mariuzza, R.A.
Deposit date:2008-02-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
4E41
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STRUCTURAL BASIS FOR THE RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED T CELL RECEPTOR G4
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
4E42
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STRUCTURAL BASIS FOR THE RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED T CELL RECEPTOR G4
Descriptor:T cell receptor G4 alpha chain, T cell receptor G4 beta chain, CHLORIDE ION, ...
Authors:Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
3G39
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STRUCTURE OF A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR
Descriptor:Variable lymphocyte receptor VLRB.2D
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3A
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STRUCTURE OF A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR IN COMPLEX WITH A PROTEIN ANTIGEN
Descriptor:Variable lymphocyte receptor VLRB.2D, Lysozyme C
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3B
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STRUCTURE OF A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR MUTANT IN COMPLEX WITH A PROTEIN ANTIGEN
Descriptor:variable lymphocyte receptor VLRB.2D, Lysozyme C
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
2PTT
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STRUCTURE OF NK CELL RECEPTOR 2B4 (CD244) BOUND TO ITS LIGAND CD48
Descriptor:CD48 antigen, Natural killer cell receptor 2B4, SULFATE ION
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTU
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STRUCTURE OF NK CELL RECEPTOR 2B4 (CD244)
Descriptor:Natural killer cell receptor 2B4
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTV
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STRUCTURE OF NK CELL RECEPTOR LIGAND CD48
Descriptor:CD48 antigen
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007