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1H9J
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TWO CRYSTAL STRUCTURES OF THE CYTOPLASMIC MOLYBDATE-BINDING PROTEIN MODG SUGGEST A NOVEL COOPERATIVE BINDING MECHANISM AND PROVIDE INSIGHTS INTO LIGAND-BINDING SPECIFICITY. PHOSPHATE-GROWN FORM WITH MOLYBDATE AND PHOSPHATE BOUND
Descriptor:MOLYBDENUM-BINDING-PROTEIN, MOLYBDATE ION, PHOSPHATE ION
Authors:Delarbre, L., Stevenson, C.E.M., White, D.J., Mitchenall, L.A., Pau, R.N., Lawson, D.M.
Deposit date:2001-03-13
Release date:2001-05-11
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two Crystal Structures of the Cytoplasmic Molybdate-Binding Protein Modg Suggest a Novel Cooperative Binding Mechanism and Provide Insights Into Ligand-Binding Specificity
J.Mol.Biol., 308, 2001
1H9K
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TWO CRYSTAL STRUCTURES OF THE CYTOPLASMIC MOLYBDATE-BINDING PROTEIN MODG SUGGEST A NOVEL COOPERATIVE BINDING MECHANISM AND PROVIDE INSIGHTS INTO LIGAND-BINDING SPECIFICITY. PHOSPHATE-GROWN FORM WITH TUNGSTATE AND PHOSPHATE BOUND
Descriptor:MOLYBDENUM-BINDING-PROTEIN, TUNGSTATE(VI)ION, PHOSPHATE ION
Authors:Delarbre, L., Stevenson, C.E.M., White, D.J., Mitchenall, L.A., Pau, R.N., Lawson, D.M.
Deposit date:2001-03-13
Release date:2001-05-11
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two Crystal Structures of the Cytoplasmic Molybdate-Binding Protein Modg Suggest a Novel Cooperative Binding Mechanism and Provide Insights Into Ligand-Binding Specificity
J.Mol.Biol., 308, 2001
1H9M
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TWO CRYSTAL STRUCTURES OF THE CYTOPLASMIC MOLYBDATE-BINDING PROTEIN MODG SUGGEST A NOVEL COOPERATIVE BINDING MECHANISM AND PROVIDE INSIGHTS INTO LIGAND-BINDING SPECIFICITY. PEG-GROWN FORM WITH MOLYBDATE BOUND
Descriptor:MOLYBDENUM-BINDING-PROTEIN, MOLYBDATE ION
Authors:Delarbre, L., Stevenson, C.E.M., White, D.J., Mitchenall, L.A., Pau, R.N., Lawson, D.M.
Deposit date:2001-03-13
Release date:2001-05-11
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Two Crystal Structures of the Cytoplasmic Molybdate-Binding Protein Modg Suggest a Novel Cooperative Binding Mechanism and Provide Insights Into Ligand-Binding Specificity
J.Mol.Biol., 308, 2001
2EWA
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DUAL BINDING MODE OF PYRIDINYLIMIDAZOLE TO MAP KINASE P38
Descriptor:Mitogen-activated protein kinase 14, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
Authors:Delarbre, L., Pouzieux, S., Guilloteau, J.-P., Michot, N.
Deposit date:2005-11-02
Release date:2006-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NMR characterization of kinase p38 dynamics in free and ligand-bound forms.
Angew.Chem.Int.Ed.Engl., 45, 2006
4UYN
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SAR156497 AN EXQUISITELY SELECTIVE INHIBITOR OF AURORA KINASES
Descriptor:AURORA KINASE A, ethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate
Authors:Carry, J.C., Clerc, F., Minoux, H., Schio, L., Mauger, J., Nair, A., Parmantier, E., Lemoigne, R., Delorme, C., Nicolas, J.P., Krick, A., Abecassis, P.Y., Crocq-Stuerga, V., Pouzieux, S., Delarbre, L., Maignan, S., Bertrand, T., Bjergarde, K., Ma, N., Lachaud, S., Guizani, H., Lebel, R., Doerflinger, G., Monget, S., Perron, S., Gasse, F., Angouillant-Boniface, O., Filoche-Romme, B., Murer, M., Gontier, S., Prevost, C., Monteiro, M.L., Combeau, C.
Deposit date:2014-09-02
Release date:2014-11-19
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sar156497, an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015
4UZD
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SAR156497 AN EXQUISITELY SELECTIVE INHIBITOR OF AURORA KINASES
Descriptor:AURORA KINASE A, ethyl (9S)-9-[3-(1H-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate
Authors:Pouzieux, S., Delarbre, L., Crenne, J.Y.
Deposit date:2014-09-05
Release date:2014-11-19
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015
4UZH
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SAR156497 AN EXQUISITELY SELECTIVE INHIBITOR OF AURORA KINASES
Descriptor:AURORA 2 KINASE DOMAIN, (4S)-4-(2-fluorophenyl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b][1,7]naphthyridin-5-one
Authors:Pouzieux, S., Maignan, S., Crenne, J.Y.
Deposit date:2014-09-05
Release date:2014-11-19
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015