Author results

1H34
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CRYSTAL STRUCTURE OF LIMA BEAN TRYPSIN INHIBITOR
Descriptor:BOWMAN-BIRK TYPE PROTEINASE INHIBITOR
Authors:Debreczeni, J.E., Bunkoczi, G., Girmann, B., Sheldrick, G.M.
Deposit date:2002-08-21
Release date:2003-02-06
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:In-House Phase Determination of the Lima Bean Trypsin Inhibitor: A Low-Resolution Sulfur-Sad Case
Acta Crystallogr.,Sect.D, 59, 2003
1OKH
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VISCOTOXIN A3 FROM VISCUM ALBUM L.
Descriptor:VISCOTOXIN A3, PHOSPHATE ION, SULFATE ION
Authors:Debreczeni, J.E., Girmann, B., Zeeck, A., Sheldrick, G.M.
Deposit date:2003-07-24
Release date:2003-12-04
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of Viscotoxin A3: Disulfide Location from Weak Sad Data
Acta Crystallogr.,Sect.D, 59, 2003
2BL0
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PHYSARUM POLYCEPHALUM MYOSIN II REGULATORY DOMAIN
Descriptor:MAJOR PLASMODIAL MYOSIN HEAVY CHAIN, MYOSIN REGULATORY LIGHT CHAIN, CALCIUM ION
Authors:Debreczeni, J.E., Farkas, L., Harmat, V., Nyitray, L.
Deposit date:2005-02-23
Release date:2005-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Evidence for Non-Canonical Binding of Ca2+ to a Canonical EF-Hand of a Conventional Myosin.
J.Biol.Chem., 280, 2005
2BP1
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STRUCTURE OF THE AFLATOXIN ALDEHYDE REDUCTASE IN COMPLEX WITH NADPH
Descriptor:AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRATE ANION
Authors:Debreczeni, J.E., Lukacik, P., Kavanagh, K., Dubinina, E., Bray, J., Colebrook, S., Haroniti, A., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Gileadi, O., Oppermann, U.
Deposit date:2005-04-17
Release date:2005-05-11
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Aflatoxin Aldehyde Reductase in Complex with Nadph
To be Published
2BUJ
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CRYSTAL STRUCTURE OF THE HUMAN SERINE-THREONINE KINASE 16 IN COMPLEX WITH STAUROSPORINE
Descriptor:SERINE/THREONINE-PROTEIN KINASE 16, CHLORIDE ION, STAUROSPORINE
Authors:Debreczeni, J.E., Eswaran, J., Bullock, A., Filippakopoulos, P., Kavanagh, K., Amos, A., Fedorov, O., Sobott, F., Ball, L.J., von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Knapp, S.
Deposit date:2005-06-13
Release date:2005-07-05
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Human Serine-Threonine Kinase 16 in Complex with Staurosporine
To be Published
2BZH
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CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1
Descriptor:PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1, RUTHENIUM-PYRIDOCARBAZOLE-1, 1,2-ETHANEDIOL, ...
Authors:Debreczeni, J.E., Bullock, A., Knapp, S., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-08-18
Release date:2005-12-08
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human Pim1 in Complex with Ruthenium Organometallic Ligands
To be Published
2BZI
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CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU2
Descriptor:PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1, RU-PYRIDOCARBAZOLE-2
Authors:Debreczeni, J.E., Bullock, A., Knapp, S., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-08-18
Release date:2005-12-08
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human Pim1 in Complex with Ruthenium Organometallic Ligands
To be Published
2BZJ
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CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU3
Descriptor:PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1, RUTHENIUM-PYRIDOCARBAZOLE-3
Authors:Debreczeni, J.E., Bullock, A., Knapp, S., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-08-18
Release date:2005-10-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Human Pim1 in Complex with Ruthenium Organometallic Ligands
To be Published
2BZK
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CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH AMPPNP AND PIMTIDE
Descriptor:PIMTIDE, PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Debreczeni, J.E., Bullock, A., Knapp, S., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-08-18
Release date:2005-11-03
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of the Human Pim1 in Complex with Amppnp and Pimtide
To be Published
2C2H
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CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
Descriptor:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-09-29
Release date:2005-10-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Human Rac3 in Complex with Gdp
To be Published
2C60
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CRYSTAL STRUCTURE OF HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2 PHOX DOMAIN AT 1.25 A RESOLUTION
Descriptor:HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2, CALCIUM ION, GLYCEROL
Authors:Debreczeni, J.E., Salah, E., Papagrigoriou, E., Burgess, N., von Delft, F., Gileadi, O., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Knapp, S.
Deposit date:2005-11-04
Release date:2005-11-29
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase Kinase 3 Isoform 2 Fox Domain at 1.25 A Resolution
To be Published
2CFY
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN REDUCTASE 1
Descriptor:THIOREDOXIN REDUCTASE 1, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Debreczeni, J.E., Johansson, C., Kavanagh, K., Savitsky, P., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U.
Deposit date:2006-02-26
Release date:2006-03-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Thioredoxin Reductase 1
To be Published
2CLP
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CRYSTAL STRUCTURE OF HUMAN AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3
Descriptor:AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION
Authors:Debreczeni, J.E., Marsden, B.D., Johansson, C., Kavanagh, K., Guo, K., Smee, C., Gileadi, O., Turnbull, A., Papagrigoriou, E., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Oppermann, U.
Deposit date:2006-04-28
Release date:2006-05-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Human Aflatoxin B1 Aldehyde Reductase Member 3
To be Published
2J0I
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CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4
Descriptor:SERINE/THREONINE-PROTEIN KINASE PAK 4, 1,2-ETHANEDIOL
Authors:Debreczeni, J.E., Eswaran, J., Ugochukwu, E., Papagrigoriou, E., Turnbull, A., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Sundstrom, M., Knapp, S.
Deposit date:2006-08-03
Release date:2006-08-17
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Human P21-Activated Kinase 4
To be Published
2JAM
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE I G
Descriptor:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G, POLYPEPTIDE, 1,2-ETHANEDIOL, ...
Authors:Debreczeni, J.E., Bullock, A., Keates, T., Niesen, F.H., Salah, E., Shrestha, L., Smee, C., Sobott, F., Pike, A.C.W., Bunkoczi, G., von Delft, F., Turnbull, A., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S.
Deposit date:2006-11-29
Release date:2007-03-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G
To be Published
2JC6
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE 1D
Descriptor:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
Authors:Debreczeni, J.E., Rellos, P., Fedorov, O., Niesen, F.H., Bhatia, C., Shrestha, L., Salah, E., Smee, C., Colebrook, S., Berridge, G., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Pike, A.C.W., von Delft, F., Knapp, S., Sundstrom, M., Weigelt, J., Arrowsmith, C.H., Edwards, A.
Deposit date:2006-12-19
Release date:2007-02-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published
2BV5
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 AT 1.8A RESOLUTION
Descriptor:TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION, ...
Authors:Debreczeni, J.E., Barr, A.J., Eswaran, J., Smee, C., Burgess, N., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Knapp, S.
Deposit date:2005-06-22
Release date:2005-07-14
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.
Biochem. J., 395, 2006
2BVA
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CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4
Descriptor:P21-ACTIVATED KINASE 4
Authors:Debreczeni, J.E., Bunkoczi, G., Eswaran, J., Filippakopoulos, P., Das, S., Fedorov, O., Sundstrom, M., Arrowsmith, C., Edwards, A., von Delft, F., Knapp, S.
Deposit date:2005-06-23
Release date:2005-07-14
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks.
Structure, 15, 2007
2BZL
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE N14 AT 1. 65 A RESOLUTION
Descriptor:TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 14, SULFATE ION, ...
Authors:Debreczeni, J.E., Barr, A., Eswaran, J., Das, S., Burgess, N., Longman, E., Fedorov, O., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Knapp, S.
Deposit date:2005-08-18
Release date:2005-09-13
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of Human Protein Tyrosine Phosphatase 14 (Ptpn14) at 1.65-A Resolution.
Proteins, 63, 2006
2C7S
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE KAPPA AT 1.95A RESOLUTION
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA, ACETATE ION
Authors:Debreczeni, J.E., Ugochukwu, E., Eswaran, J., Barr, A., Das, S., Burgess, N., Gileadi, O., Longman, E., von Delft, F., Knapp, S., Sundstron, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-11-28
Release date:2007-01-02
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.
Protein Sci., 15, 2006
2C9W
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CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 1.9A RESOLUTION
Descriptor:SUPPRESSOR OF CYTOKINE SIGNALING 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ...
Authors:Debreczeni, J.E., Bullock, A., Amos, A., Savitsky, P., Barr, A., Burgess, N., Sundstrom, M., Weigelt, J., Arrowsmith, C., Edwards, A., Knapp, S.
Deposit date:2005-12-14
Release date:2006-02-22
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
2CDZ
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CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH CGP74514A
Descriptor:SERINE/THREONINE-PROTEIN KINASE PAK 4, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE, SULFATE ION, ...
Authors:Debreczeni, J.E., Ugochukwu, E., Eswaran, J., Filippakopoulos, P., Das, S., Fedorov, O., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Knapp, S.
Deposit date:2006-01-31
Release date:2006-02-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks.
Structure, 15, 2007
2IVX
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CRYSTAL STRUCTURE OF HUMAN CYCLIN T2 AT 1.8 A RESOLUTION
Descriptor:CYCLIN-T2, 1,2-ETHANEDIOL
Authors:Debreczeni, J.E., Bullock, A.N., Fedorov, O., Savitsky, P., Berridge, G., Das, S., Pike, A.C.W., Turnbull, A., Ugochukwu, E., Papagrigoriou, E., Gorrec, F., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., von Delft, F., Knapp, S.
Deposit date:2006-06-21
Release date:2006-07-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J., 27, 2008
2IZV
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CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 2.55A RESOLUTION
Descriptor:SUPPRESSOR OF CYTOKINE SIGNALING 4, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ...
Authors:Debreczeni, J.E., Bullock, A., Papagrigoriou, E., Turnbull, A., Pike, A.C.W., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Knapp, S.
Deposit date:2006-07-26
Release date:2006-08-02
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.
Structure, 15, 2007
2V9B
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X-RAY STRUCTURE OF VISCOTOXIN B2 FROM VISCUM ALBUM
Descriptor:VISCOTOXIN-B, SULFATE ION
Authors:Debreczeni, J.E., Pal, A., Kahle, B., Zeeck, A., Sheldrick, G.M.
Deposit date:2007-08-23
Release date:2008-06-17
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structures of viscotoxins A1 and B2 from European mistletoe solved using native data alone.
Acta Crystallogr. D Biol. Crystallogr., 64, 2008