Author results

1UYJ
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CLOSTRIDIUM PERFRINGENS EPSILON TOXIN SHOWS STRUCTURAL SIMILARITY WITH THE PORE FORMING TOXIN AEROLYSIN
Descriptor:EPSILON-TOXIN, URANIUM ATOM
Authors:Cole, A.R., Gibert, M., Poppoff, M., Moss, D.S., Titball, R.W., Basak, A.K.
Deposit date:2004-03-02
Release date:2004-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Clostridium Perfringens Epsilon-Toxin Shows Structural Similarity to the Pore-Forming Toxin Aerolysin
Nat.Struct.Mol.Biol., 11, 2004
3K1L
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CRYSTAL STRUCTURE OF FANCL
Descriptor:Fancl, ZINC ION, MALTOSE, ...
Authors:Cole, A.R., Walden, H.
Deposit date:2009-09-28
Release date:2010-02-16
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the catalytic subunit FANCL of the Fanconi anemia core complex
Nat.Struct.Mol.Biol., 17, 2010
4L5N
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CRYSTALLOGRAPHIC STRUCTURE OF HHV-1 URACIL-DNA GLYCOSYLASE COMPLEXED WITH THE BACILLUS PHAGE PZA INHIBITOR PROTEIN P56
Descriptor:Uracil-DNA glycosylase, Early protein GP1B, ACETATE ION
Authors:Cole, A.R., Sapir, O., Ryzhenkova, K., Baltulionis, G., Hornyak, P., Savva, R.
Deposit date:2013-06-11
Release date:2013-08-07
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase.
Nucleic Acids Res., 41, 2013
4U04
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STRUCTURE OF A EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN
Descriptor:Adenosine monophosphate-protein transferase FICD, D(-)-TARTARIC ACID, TETRAETHYLENE GLYCOL
Authors:Cole, A.R., Bunney, T.D., Katan, M.
Deposit date:2014-07-11
Release date:2014-12-10
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
Structure, 22, 2014
4U07
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ATP BOUND TO EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN
Descriptor:Adenosine monophosphate-protein transferase FICD, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Cole, A.R., Bunney, T.D., Katan, M.
Deposit date:2014-07-11
Release date:2014-12-10
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
Structure, 22, 2014
4U0S
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STRUCTURE OF EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN WITH ADP
Descriptor:Adenosine monophosphate-protein transferase FICD, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Cole, A.R., Katan, M., Bunney, T.D.
Deposit date:2014-07-14
Release date:2014-12-10
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
Structure, 22, 2014
4U0U
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WILD TYPE EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN WITH ADP
Descriptor:Adenosine monophosphate-protein transferase FICD, TETRAETHYLENE GLYCOL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Cole, A.R., Bunney, T.D., Katan, M.
Deposit date:2014-07-14
Release date:2014-12-10
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
Structure, 22, 2014
4U0Z
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EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN WITH BOUND APCPP
Descriptor:Adenosine monophosphate-protein transferase FICD, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION
Authors:Cole, A.R., Bunney, T.D., Katan, M.
Deposit date:2014-07-14
Release date:2014-12-10
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
Structure, 22, 2014
6F2R
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A HETEROTETRAMER OF HUMAN HSPB2 AND HSPB3
Descriptor:HspB2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2, Heat shock protein beta-2, Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-2, ...
Authors:Clark, A.R., Cole, A.R., Boelens, W.C., Keep, N.H., Slingsby, C.
Deposit date:2017-11-27
Release date:2018-07-25
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3.
J.Mol.Biol., 430, 2018
2W2K
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CRYSTAL STRUCTURE OF THE APO FORMS OF RHODOTORULA GRAMINIS D- MANDELATE DEHYDROGENASE AT 1.8A.
Descriptor:D-MANDELATE DEHYDROGENASE
Authors:Vachieri, S.G., Cole, A.R., Bagneris, C., Baker, D.P., Fewson, C.A., Basak, A.K.
Deposit date:2008-11-02
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase
To be Published
2W2L
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CRYSTAL STRUCTURE OF THE HOLO FORMS OF RHODOTORULA GRAMINIS D- MANDELATE DEHYDROGENASE AT 2.5A.
Descriptor:D-MANDELATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Vachieri, S.G., Cole, A.R., Bagneris, C., Baker, D.P., Fewson, C.A., Basak, A.K.
Deposit date:2008-11-02
Release date:2009-11-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase
To be Published
3ZJX
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CLOSTRIDIUM PERFRINGENS EPSILON TOXIN MUTANT H149A BOUND TO OCTYL GLUCOSIDE
Descriptor:EPSILON-TOXIN, B-OCTYLGLUCOSIDE, PHOSPHATE ION
Authors:Bokori-Brown, M., Kokkinidou, M.C., Savva, C.G., Fernandes da Costa, S.P., Naylor, C.E., Cole, A.R., Basak, A.K., Titball, R.W.
Deposit date:2013-01-20
Release date:2013-03-27
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Clostridium Perfringens Epsilon Toxin H149A Mutant as a Platform for Receptor Binding Studies.
Protein Sci., 22, 2013
3ZQS
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HUMAN FANCL CENTRAL DOMAIN
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE FANCL, PROLINE, HEXAETHYLENE GLYCOL, ...
Authors:Hodson, C., Cole, A.R., Purkiss-Trew, A., Walden, H.
Deposit date:2011-06-10
Release date:2011-07-20
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Human Fancl, the E3 Ligase in the Fanconi Anemia Pathway.
J.Biol.Chem., 286, 2011
4CAH
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STRUCTURE OF INNER DYSF DOMAIN OF HUMAN DYSFERLIN
Descriptor:DYSFERLIN, PHOSPHATE ION
Authors:Sula, A., Cole, A.R., Yeats, C., Orengo, C., Keep, N.H.
Deposit date:2013-10-08
Release date:2014-01-29
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Crystal Structures of the Human Dysferlin Inner Dysf Domain
Bmc Struct.Biol., 14, 2014
4CAI
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STRUCTURE OF INNER DYSF DOMAIN OF HUMAN DYSFERLIN
Descriptor:DYSFERLIN, PHOSPHATE ION
Authors:Sula, A., Cole, A.R., Yeats, C., Orengo, C., Keep, N.H.
Deposit date:2013-10-08
Release date:2014-01-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of the Human Dysferlin Inner Dysf Domain
Bmc Struct.Biol., 14, 2014
4F4L
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OPEN CHANNEL CONFORMATION OF A VOLTAGE GATED SODIUM CHANNEL
Descriptor:Ion transport protein
Authors:McCusker, E.C., Bagneris, C., Naylor, C.E., Cole, A.R., D'Avanzo, N., Nichols, C.G., Wallace, B.A.
Deposit date:2012-05-10
Release date:2012-10-03
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing.
Nat Commun, 3, 2012
4H56
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CRYSTAL STRUCTURE OF THE CLOSTRIDIUM PERFRINGENS NETB TOXIN IN THE MEMBRANE INSERTED FORM
Descriptor:Necrotic enteritis toxin B
Authors:Savva, C.G., Fernandes da Costa, S.P., Bokori-Brown, M., Naylor, C., Cole, A.R., Moss, D.S., Titball, R.W., Basak, A.K.
Deposit date:2012-09-18
Release date:2012-12-26
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens.
J.Biol.Chem., 288, 2013
4KYP
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BETA-SCORPION TOXIN FOLDED IN THE PERIPLASM OF E.COLI
Descriptor:Beta-insect excitatory toxin Bj-xtrIT, TRIETHYLENE GLYCOL, TETRAETHYLENE GLYCOL
Authors:O'Reilly, A.O., Cole, A.R., Lopes, J.L., Lampert, A., Wallace, B.A.
Deposit date:2013-05-29
Release date:2014-02-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chaperone-mediated native folding of a beta-scorpion toxin in the periplasm of Escherichia coli.
Biochim.Biophys.Acta, 1840, 2014
4WJT
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STATIONARY PHASE SURVIVAL PROTEIN YUIC FROM B.SUBTILIS COMPLEXED WITH NAG
Descriptor:Uncharacterized protein YuiC, N-ACETYL-D-GLUCOSAMINE, DIMETHYL SULFOXIDE, ...
Authors:Quay, D.H.X., Cole, A.R., Cryar, A., Thalassinos, K., Williams, M.A., Bhakta, S., Keep, N.H.
Deposit date:2014-10-01
Release date:2015-07-08
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structure of the stationary phase survival protein YuiC from B.subtilis.
Bmc Struct.Biol., 15, 2015
4WLI
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STATIONARY PHASE SURVIVAL PROTEIN YUIC FROM B.SUBTILIS
Descriptor:YuiC, 1,2-ETHANEDIOL
Authors:Quay, D.H.X., Cole, A.R., Cryar, A., Thalassinos, K., Williams, M.A., Bhakta, S., Keep, N.H.
Deposit date:2014-10-07
Release date:2015-07-08
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of the stationary phase survival protein YuiC from B.subtilis.
Bmc Struct.Biol., 15, 2015
4WLK
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STATIONARY PHASE SURVIVAL PROTEIN YUIC FROM B.SUBTILIS COMPLEXED WITH REACTION PRODUCT
Descriptor:YuiC, N-[(1R,2S,3R,4R,5R)-2-[(2S,3R,4R,5S,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-6,8-dioxabicyclo[3.2.1]octan-4-yl]ethanamide
Authors:Quay, D.H.X., Cole, A.R., Cryar, A., Thalassinos, K., Williams, M.A., Bhakta, S., Keep, N.H.
Deposit date:2014-10-07
Release date:2015-07-08
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structure of the stationary phase survival protein YuiC from B.subtilis.
Bmc Struct.Biol., 15, 2015
4EY0
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STRUCTURE OF TANDEM SH2 DOMAINS FROM PLCGAMMA1
Descriptor:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Authors:Cole, A.R., Mas-Droux, C.P., Bunney, T.D., Katan, M.
Deposit date:2012-05-01
Release date:2012-10-31
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation.
Structure, 20, 2012
4FBN
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INSIGHTS INTO STRUCTURAL INTEGRATION OF THE PLCGAMMA REGULATORY REGION AND MECHANISM OF AUTOINHIBITION AND ACTIVATION BASED ON KEY ROLES OF SH2 DOMAINS
Descriptor:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Authors:Cole, A.R., Mas-Droux, C.P., Bunney, T.D., Katan, M.
Deposit date:2012-05-23
Release date:2012-10-31
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation.
Structure, 20, 2012
4Z39
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STRUCTURE OF OBP3 FROM THE VETCH APHID MEGOURA VICIAE
Descriptor:Odorant-binding protein, GLYCEROL, SULFATE ION
Authors:Northey, T., Venthur, H., De Biasio, F., Chauviac, F.-X., Cole, A.R., Field, L.M., Zhou, J.-J., Keep, N.H.
Deposit date:2015-03-31
Release date:2016-04-13
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures and Binding Dynamics of Odorant-Binding Protein 3 from two aphid species Megoura viciae and Nasonovia ribisnigri.
Sci Rep, 6, 2016
4Z45
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STRUCTURE OF OBP3 FROM THE CURRANT-LETTUCE APHID NASONOVIA RIBISNIGRI
Descriptor:Odorant-binding protein NribOBP3
Authors:Northey, T., Venthur, H., De Biasio, F., Chauviac, F.-X., Cole, A.R., Field, L.M., Zhou, J.-J., Keep, N.H.
Deposit date:2015-04-01
Release date:2016-04-13
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal Structures and Binding Dynamics of Odorant-Binding Protein 3 from two aphid species Megoura viciae and Nasonovia ribisnigri.
Sci Rep, 6, 2016
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