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3FI7
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CRYSTAL STRUCTURE OF THE AUTOLYSIN AUTO (LMO1076) FROM LISTERIA MONOCYTOGENES, CATALYTIC DOMAIN
Descriptor:Lmo1076 protein, SULFATE ION
Authors:Bublitz, M., Polle, L., Holland, C., Nimtz, M., Heinz, D.W., Schubert, W.D.
Deposit date:2008-12-11
Release date:2009-04-07
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for autoinhibition and activation of Auto, a virulence-associated peptidoglycan hydrolase of Listeria monocytogenes.
Mol.Microbiol., 71, 2009
4XOU
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CRYSTAL STRUCTURE OF THE SR CA2+-ATPASE IN THE CA2-E1-MGAMPPCP FORM DETERMINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY USING AN X-RAY FREE-ELECTRON LASER.
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, CALCIUM ION, POTASSIUM ION, ...
Authors:Bublitz, M., Nass, K., Drachmann, N.D., Markvardsen, A.J., Gutmann, M.J., Barends, T.R.M., Mattle, D., Shoeman, R.L., Doak, R.B., Boutet, S., Messerschmidt, M., Seibert, M.M., Williams, G.J., Foucar, L., Reinhard, L., Sitsel, O., Gregersen, J.L., Clausen, J.D., Boesen, T., Gotfryd, K., Wang, K.-T., Olesen, C., Moller, J.V., Nissen, P., Schlichting, I.
Deposit date:2015-01-16
Release date:2015-06-10
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser.
Iucrj, 2, 2015
3N5K
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STRUCTURE OF THE (SR)CA2+-ATPASE E2-ALF4- FORM
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Bublitz, M., Olesen, C., Poulsen, H., Morth, J.P., Moller, J.V., Nissen, P.
Deposit date:2010-05-25
Release date:2011-06-08
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
3N8G
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STRUCTURE OF THE (SR)CA2+-ATPASE CA2-E1-CAAMPPCP FORM
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform SERCA 1a, CALCIUM ION, POTASSIUM ION, ...
Authors:Bublitz, M., Olesen, C., Poulsen, H., Morth, J.P., Moller, J.V., Nissen, P.
Deposit date:2010-05-28
Release date:2011-06-08
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
3BZ5
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FUNCTIONAL DOMAIN OF INLJ FROM LISTERIA MONOCYTOGENES INCLUDES A CYSTEINE LADDER
Descriptor:Internalin-J, SULFATE ION, CHLORIDE ION
Authors:Bublitz, M., Holland, C., Sabet, C., Reichelt, J., Cossart, P., Heinz, D.W., Bierne, H., Schubert, W.D.
Deposit date:2008-01-17
Release date:2008-06-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder.
J.Mol.Biol., 378, 2008
5NCQ
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STRUCTURE OF THE (SR) CA2+-ATPASE BOUND TO A TETRAHYDROCARBAZOLE AND TNP-ATP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE, POTASSIUM ION, ...
Authors:Bublitz, M., Kjellerup, L., O'Hanlon Cohrt, K., Gordon, S., Mortensen, A.L., Clausen, J.D., Pallin, D., Hansen, J.B., Brown, W.D., Fuglsang, A., Winther, A.-M.L.
Deposit date:2017-03-06
Release date:2018-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity.
PLoS ONE, 13, 2018
4NAB
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STRUCTURE OF THE (SR)CA2+-ATPASE MUTANT E309Q IN THE CA2-E1-MGAMPPCP FORM
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, CALCIUM ION, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Bublitz, M., Clausen, J.D., Arnou, B., Montigny, C., Jaxel, C., Nissen, P., Moller, J.V., Andersen, J.P., le Maire, M.
Deposit date:2013-10-22
Release date:2013-12-18
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation.
Embo J., 32, 2013
4H1W
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E1 STRUCTURE OF THE (SR) CA2+-ATPASE IN COMPLEX WITH SARCOLIPIN
Descriptor:SERCA1a, Sarcolipin, POTASSIUM ION, ...
Authors:Bublitz, M., Winther, A.-M.L., Karlsen, J., Moller, J.V., Hansen, J.B., Buch-Pedersen, M.J., Nissen, P.
Deposit date:2012-09-11
Release date:2013-03-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.
Nature, 495, 2013
5A3Q
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CRYSTAL STRUCTURE OF THE (SR) CALCIUM ATPASE E2-VANADATE COMPLEX BOUND TO THAPSIGARGIN AND TNP-AMPPCP
Descriptor:SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Clausen, J.D., Bublitz, M., Arnou, B., Olesen, C., Andersen, J.P., Moller, J.V., Nissen, P.
Deposit date:2015-06-02
Release date:2016-04-13
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase.
Structure, 24, 2016
3FGO
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CRYSTAL STRUCTURE OF THE E2 MAGNESIUM FLUORIDE COMPLEX OF THE (SR) CA2+-ATPASE WITH BOUND CPA AND AMPPCP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, TETRAFLUOROMAGNESATE(2-), ...
Authors:Laursen, M., Bublitz, M., Moncoq, K., Olesen, C., Moller, J.V., Young, H.S., Nissen, P., Morth, J.P.
Deposit date:2008-12-08
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 2009
3FPB
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THE STRUCTURE OF SARCOPLASMIC RETICULUM CA2+-ATPASE BOUND TO CYCLOPIAZONIC ACID WITH ATP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, TETRAFLUOROMAGNESATE(2-), ...
Authors:Moncoq, K., Morth, J.P., Bublitz, M., Laursen, M., Nissen, P., Young, H.S.
Deposit date:2009-01-05
Release date:2009-04-07
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 284, 2009
3FPS
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THE STRUCTURE OF SARCOPLASMIC RETICULUM CA2+-ATPASE BOUND TO CYCLOPIAZONIC AND ADP
Descriptor:Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, ...
Authors:Moncoq, K., Morth, J.P., Bublitz, M., Laursen, M., Nissen, P., Young, H.S.
Deposit date:2009-01-06
Release date:2009-04-07
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 284, 2009
4J2T
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INHIBITOR-BOUND CA2+ ATPASE
Descriptor:SERCA1a, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-3a,4-bis(butanoyloxy)-3-hydroxy-3,6,9-trimethyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Paulsen, E.S., Villadsen, J., Tenori, E., Liu, H., Lie, M.A., Bonde, D.F., Bublitz, M., Olesen, C., Autzen, H.E., Dach, I., Sehgal, P., Moller, J.V., Schiott, B., Nissen, P., Christensen, S.B.
Deposit date:2013-02-05
Release date:2013-06-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase.
J.Med.Chem., 56, 2013
4UU0
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CRYSTAL STRUCTURE OF (SR) CALCIUM-ATPASE E2(TG) IN THE PRESENCE OF 14:1 PC
Descriptor:SERCA1A, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Drachmann, N.D., Olesen, C., Moeller, J.V., Guo, Z., Nissen, P., Bublitz, M.
Deposit date:2014-07-24
Release date:2014-10-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Comparing Crystal Structures of Ca(2+) -ATPase in the Presence of Different Lipids.
FEBS J., 281, 2014
4UU1
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CRYSTAL STRUCTURE OF (SR) CALCIUM-ATPASE E2(TG) IN THE PRESENCE OF DOPC
Descriptor:SARCOPLASMIC ENDOPLASMIC RETICULUM CALCIUM ATPASE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Drachmann, N.D., Olesen, C., Moeller, J.V., Guo, Z., Nissen, P., Bublitz, M.
Deposit date:2014-07-24
Release date:2014-10-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Comparing Crystal Structures of Ca(2+) -ATPase in the Presence of Different Lipids.
FEBS J., 281, 2014
5A3R
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CRYSTAL STRUCTURE OF THE (SR) CALCIUM ATPASE E2.BEF3- COMPLEX BOUND TO TNP-AMPPCP
Descriptor:SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1, Spiro(2,4,6-trinitrobenzene[1,2a]-O2',O3'-methylene-adenosine (beta,gamma-methylene)triphosphate, POTASSIUM ION, ...
Authors:Clausen, J.D., Bublitz, M., Arnou, B., Olesen, C., Andersen, J.P., Moller, J.V., Nissen, P.
Deposit date:2015-06-02
Release date:2016-04-13
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase.
Structure, 24, 2016
5A3S
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CRYSTAL STRUCTURE OF THE (SR) CALCIUM ATPASE E2-VANADATE COMPLEX BOUND TO THAPSIGARGIN AND TNP-ATP
Descriptor:SARCOPLASMIC RETICULUM CALCIUM ATPASE 1 MOLECULE SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Clausen, J.D., Bublitz, M., Arnou, B., Olesen, C., Andersen, J.P., Moller, J.V., Nissen, P.
Deposit date:2015-06-03
Release date:2016-04-13
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase.
Structure, 24, 2016
5FL7
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STRUCTURE OF THE F1C10 COMPLEX FROM YARROWIA LIPOLYTICA ATP SYNTHASE
Descriptor:ATP SYNTHASE SUBUNIT ALPHA, ATP SYNTHASE SUBUNIT BETA, ATP SYNTHASE SUBUNIT GAMMA CHAIN, ...
Authors:Parey, K., Bublitz, M., Meier, T.
Deposit date:2015-10-22
Release date:2016-06-29
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology.
Mol.Cell, 63, 2016
4BEW
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SERCA BOUND TO PHOSPHATE ANALOGUE
Descriptor:SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Drachmann, N.D., Mattle, D., Laursen, M., Bublitz, M., Olesen, C., Moeller, J.V., Nissen, P., Morth, J.P.
Deposit date:2013-03-12
Release date:2014-02-19
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Serca Bound to Phosphate Analogue
To be Published