Author results

3F49
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ANION-TRIGGERED ENGINEERED SUBTILISIN SUBT_BACAM
Descriptor:Subtilisin BPN, SODIUM ION
Authors:Gallagher, D.T., Bryan, P.N.
Deposit date:2008-10-31
Release date:2008-12-16
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Anion-triggered Engineered Subtilisin SUBT_BACAM
To be Published
3BGO
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AZIDE COMPLEX OF ENGINEERED SUBTILISIN SUBT_BACAM
Descriptor:Subtilisin BPN', AZIDE ION, ZINC ION
Authors:Gallagher, D.T., Bryan, P.N.
Deposit date:2007-11-27
Release date:2008-06-03
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a switchable subtilisin complexed with a substrate and with the activator azide.
Biochemistry, 48, 2009
3CO0
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SUBSTRATE COMPLEX OF FLUORIDE-SENSITIVE ENGINEERED SUBTILISIN SUBT_BACAM
Descriptor:Subtilisin BPN', ZINC ION
Authors:Gallagher, D.T., Bryan, P.N.
Deposit date:2008-03-26
Release date:2008-10-14
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure of a switchable subtilisin complexed with a substrate and with the activator azide.
Biochemistry, 48, 2009
1KN6
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SOLUTION STRUCTURE OF THE MOUSE PROHORMONE CONVERTASE 1 PRO-DOMAIN
Descriptor:Prohormone Convertase 1
Authors:Tangrea, M.A., Bryan, P.N., Sari, N., Orban, J.
Deposit date:2001-12-18
Release date:2002-07-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus.
J.Mol.Biol., 320, 2002
1ZXG
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SOLUTION STRUCTURE OF A219
Descriptor:Immunoglobulin G binding protein A
Authors:He, Y., Yeh, D.C., Alexander, P., Bryan, P.N., Orban, J.
Deposit date:2005-06-08
Release date:2005-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
Biochemistry, 44, 2005
1ZXH
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G311 MUTANT PROTEIN
Descriptor:Immunoglobulin G binding protein G
Authors:He, Y., Yeh, D.C., Alexander, P., Bryan, P.N., Orban, J.
Deposit date:2005-06-08
Release date:2005-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
Biochemistry, 44, 2005
3CNQ
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PROSUBTILISIN SUBSTRATE COMPLEX OF SUBTILISIN SUBT_BACAM
Descriptor:Subtilisin BPN', ZINC ION
Authors:Gallagher, D.T., Bryan, P.N.
Deposit date:2008-03-26
Release date:2008-05-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant.
Biochemistry, 47, 2008
1S01
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LARGE INCREASES IN GENERAL STABILITY FOR SUBTILISIN BPN(PRIME) THROUGH INCREMENTAL CHANGES IN THE FREE ENERGY OF UNFOLDING
Descriptor:Subtilisin BPN', CALCIUM ION, ISOPROPYL ALCOHOL
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1989-08-21
Release date:1990-10-15
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AK9
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SUBTILISIN MUTANT 8321
Descriptor:SUBTILISIN 8321, CALCIUM ION, SODIUM ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-05-30
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AU9
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SUBTILISIN BPN' MUTANT 8324 IN CITRATE
Descriptor:SUBTILISIN BPN', CALCIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-09-12
Release date:1997-12-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1A2Q
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SUBTILISIN BPN' MUTANT 7186
Descriptor:SUBTILISIN BPN', CALCIUM ION, ACETONE
Authors:Gilliland, G.L., Whitlow, M., Howard, A.J.
Deposit date:1998-01-08
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AQN
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SUBTILISIN MUTANT 8324
Descriptor:SUBTILISIN 8324, CALCIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-07-31
Release date:1998-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stabilityfor subtilisin BPN' through incremental changes in the free energy of unfolding
To be published
1SPB
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SUBTILISIN BPN' PROSEGMENT (77 RESIDUES) COMPLEXED WITH A MUTANT SUBTILISIN BPN' (266 RESIDUES). CRYSTAL PH 4.6. CRYSTALLIZATION TEMPERATURE 20 C DIFFRACTION TEMPERATURE-160 C
Descriptor:SUBTILISIN BPN' PROSEGMENT, SUBTILISIN BPN', SODIUM ION
Authors:Gallagher, D.T., Gilliland, G.L., Wang, L., Bryan, P.N.
Deposit date:1995-06-21
Release date:1995-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'.
Structure, 3, 1995
2JWS
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SOLUTION NMR STRUCTURES OF TWO DESIGNED PROTEINS WITH 88% SEQUENCE IDENTITY BUT DIFFERENT FOLD AND FUNCTION
Descriptor:Ga88
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2007-10-24
Release date:2008-09-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
2JWU
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SOLUTION NMR STRUCTURES OF TWO DESIGNED PROTEINS WITH 88% SEQUENCE IDENTITY BUT DIFFERENT FOLD AND FUNCTION
Descriptor:Gb88
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2007-10-25
Release date:2008-09-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
2KDL
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NMR STRUCTURES OF GA95 AND GB95, TWO DESIGNED PROTEINS WITH 95% SEQUENCE IDENTITY BUT DIFFERENT FOLDS AND FUNCTIONS
Descriptor:designed protein
Authors:He, Y., Alexander, P., Chen, Y., Bryan, P., Orban, J.
Deposit date:2009-01-12
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2KDM
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NMR STRUCTURES OF GA95 AND GB95, TWO DESIGNED PROTEINS WITH 95% SEQUENCE IDENTITY BUT DIFFERENT FOLDS AND FUNCTIONS
Descriptor:DESIGNED PROTEIN
Authors:He, Y., Alexander, P., Chen, Y., Bryan, P., Orban, J.
Deposit date:2009-01-12
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:From the Cover: A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2LHC
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GA98 SOLUTION STRUCTURE
Descriptor:Ga98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LHD
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GB98 SOLUTION STRUCTURE
Descriptor:GB98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LHE
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GB98-T25I,L20A
Descriptor:Gb98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LHG
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GB98-T25I SOLUTION STRUCTURE
Descriptor:GB98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LU1
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PFSUB2 SOLUTION NMR STRUCTURE
Descriptor:Subtilase
Authors:He, Y., Chen, Y., Ruan, B., O'Brochta, D., Bryan, P., Orban, J.
Deposit date:2012-06-06
Release date:2012-10-03
Last modified:2012-11-14
Method:SOLUTION NMR
Cite:Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum.
Proteins, 80, 2012
2MH8
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GA-79-MBP CS-ROSETTA STRUCTURES
Descriptor:GA-79-MBP, maltose binding protein
Authors:He, Y., Chen, Y., Porter, L., Bryan, P., Orban, J.
Deposit date:2013-11-19
Release date:2015-04-08
Method:SOLUTION NMR
Cite:Subdomain interactions foster the design of two protein pairs with 80% sequence identity but different folds.
Biophys.J., 108, 2015