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1DN8
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STRUCTURE OF A Z-DNA WITH TWO DIFFERENT BACKBONE CHAIN CONFORMATIONS. STABILIZATION OF THE DECADEOXYOLIGONUCLEOTIDE D(CGTACGTACG) BY (CO(NH3)6)3+ BINDING TO THE GUANINE
分子名称:DNA (5'-D(*P*CP*GP*TP*AP*CP*GP*TP*AP*CP*G)-3'), COBALT HEXAMMINE(III)
著者Brennan, R.G., Westhof, E., Sundaralingam, M.
登録日1987-05-12
公開日1988-04-16
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of a Z-DNA with two different backbone chain conformations. Stabilization of the decadeoxyoligonucleotide d(CGTACGTACG) by [Co(NH3)6]3+ binding to the guanine.
J.Biomol.Struct.Dyn., 3, 1986
4CRO
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PROTEIN-DNA CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURE OF A LAMBDA CRO-OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*TP*CP*AP*CP*CP*GP*CP*GP*GP*GP*TP*GP*AP*TP*A)-3'), PROTEIN (LAMBDA CRO)
著者Brennan, R.G., Roderick, S.L., Takeda, Y., Matthews, B.W.
登録日1992-01-15
公開日1992-01-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex.
Proc.Natl.Acad.Sci.USA, 87, 1990
2PEX
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STRUCTURE OF REDUCED C22S OHRR FROM XANTHAMONAS CAMPESTRIS
分子名称:Transcriptional regulator OhrR, FORMIC ACID
著者Brennan, R.G., Newberry, K.J.
登録日2007-04-03
公開日2007-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.
Mol.Cell, 28, 2007
2PFB
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STRUCTURE OF OXIDIZED OHRR FROM XANTHAMONAS CAMPESTRIS
分子名称:Transcriptional regulator OhrR
著者Brennan, R.G., Newberry, K.J.
登録日2007-04-04
公開日2007-12-11
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.
Mol.Cell, 28, 2007
3ECO
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CRYSTAL STRUCTURE OF MEPR, A TRANSCRIPTION REGULATOR OF THE STAPHYLOCOCCUS AUREUS MULTIDRUG EFFLUX PUMP MEPA
分子名称:MepR, SULFATE ION
著者Brennan, R.G., Kumaraswami, M.
登録日2008-09-01
公開日2009-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA.
Nucleic Acids Res., 37, 2009
1BDH
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G.
登録日1996-07-25
公開日1997-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex
J.Am.Chem.Soc., 118, 1996
1BDI
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G.
登録日1996-07-25
公開日1997-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex
J.Am.Chem.Soc., 118, 1996
1HAB
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CROSSLINKED HAEMOGLOBIN
分子名称:HEMOGLOBIN A, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Schumacher, M.A., Dixon, M.M., Kluger, R., Jones, R.T., Brennan, R.G.
登録日1996-03-13
公開日1997-11-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allosteric intermediates indicate R2 is the liganded hemoglobin end state.
Proc.Natl.Acad.Sci.USA, 94, 1997
1HAC
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CROSSLINKED HAEMOGLOBIN
分子名称:HEMOGLOBIN A, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Schumacher, M.A., Dixon, M.M., Kluger, R., Jones, R.T., Brennan, R.G.
登録日1996-03-13
公開日1997-11-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric intermediates indicate R2 is the liganded hemoglobin end state.
Proc.Natl.Acad.Sci.USA, 94, 1997
1PRU
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PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING
分子名称:PURINE REPRESSOR
著者Nagadoi, A., Morikawa, S., Nakamura, H., Enari, M., Kobayashi, K., Yamamoto, H., Sampei, G., Mizobuchi, K., Schumacher, M.A., Brennan, R.G., Nishimura, Y.
登録日1995-05-08
公開日1996-03-08
最終更新日2012-02-22
実験手法SOLUTION NMR
主引用文献Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3, 1995
1PRV
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PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING
分子名称:PURINE REPRESSOR
著者Nagadoi, A., Morikawa, S., Nakamura, H., Enari, M., Kobayashi, K., Yamamoto, H., Sampei, G., Mizobuchi, K., Schumacher, M.A., Brennan, R.G., Nishimura, Y.
登録日1995-05-08
公開日1996-03-08
最終更新日2012-02-22
実験手法SOLUTION NMR
主引用文献Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3, 1995
1QP0
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G.
登録日1999-06-01
公開日1999-06-07
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QP4
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*TP*CP*GP*AP*TP*TP*GP*CP*GP*T)-3'), PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G.
登録日1999-06-01
公開日1999-06-07
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QP7
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G.
登録日1999-06-01
公開日1999-06-04
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QPZ
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3'), PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G.
登録日1999-06-01
公開日1999-06-07
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QQA
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*GP*CP*GP*CP*TP*TP*GP*CP*GP*T)-3'), PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR), HYPOXANTHINE
著者Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G.
登録日1999-06-01
公開日1999-06-09
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QQB
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称:5'-D(*TP*AP*CP*GP*CP*AP*AP*TP*CP*GP*AP*TP*TP*GP*CP*GP*T)-3', PURINE NUCLEOTIDE SYNTHESIS REPRESSOR, HYPOXANTHINE
著者Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G.
登録日1999-06-01
公開日1999-06-09
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1R8D
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CRYSTAL STRUCTURE OF MTAN BOUND TO DNA
分子名称:26-MER, transcription activator MtaN, SULFATE ION
著者Newberry, K.J., Brennan, R.G.
登録日2003-10-23
公開日2004-08-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
J.Biol.Chem., 279, 2004
1R8E
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CRYSTAL STRUCTURE OF BMRR BOUND TO DNA AT 2.4A RESOLUTION
分子名称:5'-D(*GP*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*TP*C)-3', multidrug-efflux transporter regulator, GLYCEROL, ...
著者Newberry, K.J., Brennan, R.G.
登録日2003-10-23
公開日2004-08-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
J.Biol.Chem., 279, 2004
1WET
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STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX
分子名称:DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), GUANINE
著者Schumacher, M.A., Glasfeld, A., Zalkin, H., Brennan, R.G.
登録日1997-04-27
公開日1997-11-21
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity.
J.Biol.Chem., 272, 1997
2PUC
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CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), GUANINE
著者Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
2PUD
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CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), HYPOXANTHINE
著者Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
2PUE
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CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR ), ADENINE
著者Lu, F., Schumacher, M.A., Arvidson, D.N., Haldimann, A., Wanner, B.L., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Biochemistry, 37, 1998
2PUF
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CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), GUANINE
著者Lu, F., Schumacher, M.A., Arvidson, D.N., Haldimann, A., Wanner, B.L., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Biochemistry, 37, 1998
2PUG
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CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
分子名称:DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), HYPOXANTHINE
著者Lu, F., Schumacher, M.A., Arvidson, D.N., Haldimann, A., Wanner, B.L., Zalkin, H., Brennan, R.G.
登録日1997-10-04
公開日1998-05-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
Biochemistry, 37, 1998