Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4CRO
DownloadVisualize
BU of 4cro by Molmil
PROTEIN-DNA CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURE OF A LAMBDA CRO-OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*TP*CP*AP*CP*CP*GP*CP*GP*GP*GP*TP*GP*AP*TP*A)-3'), PROTEIN (LAMBDA CRO)
Authors:Brennan, R.G, Roderick, S.L, Takeda, Y, Matthews, B.W.
Deposit date:1992-01-15
Release date:1992-01-15
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex.
Proc.Natl.Acad.Sci.USA, 87, 1990
1DN8
DownloadVisualize
BU of 1dn8 by Molmil
STRUCTURE OF A Z-DNA WITH TWO DIFFERENT BACKBONE CHAIN CONFORMATIONS. STABILIZATION OF THE DECADEOXYOLIGONUCLEOTIDE D(CGTACGTACG) BY (CO(NH3)6)3+ BINDING TO THE GUANINE
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*P*CP*GP*TP*AP*CP*GP*TP*AP*CP*G)-3')
Authors:Brennan, R.G, Westhof, E, Sundaralingam, M.
Deposit date:1987-05-12
Release date:1988-04-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a Z-DNA with two different backbone chain conformations. Stabilization of the decadeoxyoligonucleotide d(CGTACGTACG) by [Co(NH3)6]3+ binding to the guanine.
J.Biomol.Struct.Dyn., 3, 1986
2PFB
DownloadVisualize
BU of 2pfb by Molmil
Structure of oxidized OhrR from Xanthamonas campestris
Descriptor: Transcriptional regulator OhrR
Authors:Brennan, R.G, Newberry, K.J.
Deposit date:2007-04-04
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.
Mol.Cell, 28, 2007
2PEX
DownloadVisualize
BU of 2pex by Molmil
Structure of reduced C22S OhrR from Xanthamonas Campestris
Descriptor: FORMIC ACID, Transcriptional regulator OhrR
Authors:Brennan, R.G, Newberry, K.J.
Deposit date:2007-04-03
Release date:2007-12-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.
Mol.Cell, 28, 2007
3ECO
DownloadVisualize
BU of 3eco by Molmil
Crystal structure of MepR, a transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA
Descriptor: MepR, SULFATE ION
Authors:Brennan, R.G, Kumaraswami, M.
Deposit date:2008-09-01
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA.
Nucleic Acids Res., 37, 2009
3RJP
DownloadVisualize
BU of 3rjp by Molmil
Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
Descriptor: CovR
Authors:Horstmann, N.M, Brennan, R.G, Shelburne, S.A.
Deposit date:2011-04-15
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
To be Published
1ZVV
DownloadVisualize
BU of 1zvv by Molmil
Crystal structure of a ccpa-crh-dna complex
Descriptor: DNA recognition strand CRE, Glucose-resistance amylase regulator, HPr-like protein crh, ...
Authors:Schumacher, M.A, Brennan, R.G, Hillen, W, Seidel, G.
Deposit date:2005-06-02
Release date:2006-02-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
J.Biol.Chem., 281, 2006
4L9J
DownloadVisualize
BU of 4l9j by Molmil
Crystal structure of S. aureus MepR in DNA-binding conformation
Descriptor: MepR
Authors:Birukou, I, Brennan, R.G.
Deposit date:2013-06-18
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus.
MBio, 4, 2013
4L9T
DownloadVisualize
BU of 4l9t by Molmil
Crystal structure of MepR F27L mutant from multidrug resistant S. aureus clinical isolate
Descriptor: MepR, SULFATE ION
Authors:Birukou, I, Brennan, R.G.
Deposit date:2013-06-18
Release date:2013-09-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus.
MBio, 4, 2013
4LLN
DownloadVisualize
BU of 4lln by Molmil
Crystal structure of S. aureus MepR-DNA complex
Descriptor: MepR, Palindromized mepR operator sequence
Authors:Birukou, I, Brennan, R.G.
Deposit date:2013-07-09
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.842 Å)
Cite:Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.
Nucleic Acids Res., 42, 2014
1QP0
DownloadVisualize
BU of 1qp0 by Molmil
PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QP7
DownloadVisualize
BU of 1qp7 by Molmil
PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QPZ
DownloadVisualize
BU of 1qpz by Molmil
PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QQA
DownloadVisualize
BU of 1qqa by Molmil
PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*GP*CP*GP*CP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
8SSH
DownloadVisualize
BU of 8ssh by Molmil
MtrR from Neisseria gonorrhoeae bound to Ethinyl Estradiol
Descriptor: Ethinyl estradiol, HTH-type transcriptional regulator MtrR, PHOSPHATE ION
Authors:Hooks, G.M, Brennan, R.G.
Deposit date:2023-05-08
Release date:2024-02-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR.
Nat Commun, 15, 2024
5FB2
DownloadVisualize
BU of 5fb2 by Molmil
S. aureus MepR F27L Mutant bound to oligodeoxyribonucleotide
Descriptor: DNA (5'-D(*CP*GP*TP*TP*A)-3'), GLYCEROL, MarR family regulatory protein
Authors:Birukou, I, Newman, C.E, Brennan, R.G.
Deposit date:2015-12-13
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:S. aureus MepR F27L Mutant bound to oligodeoxyribonucleotide
To Be Published
5FFZ
DownloadVisualize
BU of 5ffz by Molmil
S. aureus MepR bound to ethidium bromide
Descriptor: ETHIDIUM, MarR family regulatory protein, POTASSIUM ION
Authors:Birukou, I, Newman, C.E, Brennan, R.G.
Deposit date:2015-12-19
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:S. aureus MepR bound to ethidium bromide
To Be Published
5FFX
DownloadVisualize
BU of 5ffx by Molmil
S. aureus MepR G34K Mutant
Descriptor: GLYCEROL, MarR family regulatory protein, SULFATE ION
Authors:Newman, C.E, Birukou, I, Brennan, R.G.
Deposit date:2015-12-19
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:S. aureus MepR G34K Mutant
To Be Published
1WET
DownloadVisualize
BU of 1wet by Molmil
STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX
Descriptor: DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR)
Authors:Schumacher, M.A, Glasfeld, A, Zalkin, H, Brennan, R.G.
Deposit date:1997-04-27
Release date:1997-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity.
J.Biol.Chem., 272, 1997
7LQ2
DownloadVisualize
BU of 7lq2 by Molmil
Apo Rr RsiG- crystal form 1
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, RR RsiG
Authors:Schumacher, M.A, Brennan, R.G.
Deposit date:2021-02-12
Release date:2021-07-14
Last modified:2021-08-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Evolution of a sigma-(c-di-GMP)-anti-sigma switch.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LQ4
DownloadVisualize
BU of 7lq4 by Molmil
Rr (RsiG)2-(c-di-GMP)2-WhiG complex
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), RsiG, WhiG
Authors:Schumacher, M.A, Brennan, R.G.
Deposit date:2021-02-12
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Evolution of a sigma-(c-di-GMP)-anti-sigma switch.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LQ3
DownloadVisualize
BU of 7lq3 by Molmil
Evolution of a sigma-(c-di-GMP)-antisigma switch
Descriptor: MAGNESIUM ION, RsiG, SULFATE ION
Authors:Schumacher, M.A, Brennan, R.G.
Deposit date:2021-02-12
Release date:2021-07-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Evolution of a sigma-(c-di-GMP)-anti-sigma switch.
Proc.Natl.Acad.Sci.USA, 118, 2021
8FHW
DownloadVisualize
BU of 8fhw by Molmil
Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in complex with uridine diphosphate and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE
Authors:Washington, E.J, Brennan, R.G.
Deposit date:2022-12-15
Release date:2023-12-20
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals.
Biorxiv, 2024
8FO1
DownloadVisualize
BU of 8fo1 by Molmil
Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in apo form
Descriptor: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Authors:Washington, E.J, Brennan, R.G.
Deposit date:2022-12-29
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in apo form
To Be Published
8FW0
DownloadVisualize
BU of 8fw0 by Molmil
MtrR from Neisseria gonorrhoeae bound to beta-Estradiol
Descriptor: ESTRADIOL, GLYCEROL, HTH-type transcriptional regulator MtrR, ...
Authors:Hooks, G.H, Brennan, R.G.
Deposit date:2023-01-20
Release date:2024-01-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR.
Nat Commun, 15, 2024

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon