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5FJS
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BACTERIAL BETA-GLUCOSIDASE REVEALS THE STRUCTURAL AND FUNCTIONAL BASIS OF GENETIC DEFECTS IN HUMAN GLUCOCEREBROSIDASE 2 (GBA2)
Descriptor:GLUCOSYLCERAMIDASE, CALCIUM ION
Authors:Charoenwattanasatien, R., Pengthaisong, S., Breen, I., Mutoha, R., Sansenya, S., Hua, Y., Tankrathok, A., Wu, L., Songsiriritthigul, C., Tanaka, H., Williams, S.J., Davies, G.J., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-10-12
Release date:2016-05-11
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bacterial Beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (Gba2)
Acs Chem.Biol., 11, 2016
5NCX
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLOLYTICUM GH116 BETA-GLUCOSIDASE WITH AN COVALENT INHIBITOR
Descriptor:Glucosylceramidase, ~{N}-[(1~{R},2~{R},3~{R},4~{S},5~{S},6~{S})-2-(hydroxymethyl)-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]pentanamide, CALCIUM ION, ...
Authors:Davies, G.J., Breen, I.Z.
Deposit date:2017-03-06
Release date:2017-10-04
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase.
J. Am. Chem. Soc., 139, 2017
5BVU
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLOLYTICUM GH116 BETA-GLUCOSIDASE
Descriptor:beta-glucosidase, GLYCEROL, CALCIUM ION, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-05
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2).
Acs Chem.Biol., 11, 2016
5BX2
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH 2-DEOXY-2-FLUOROGLUCOSIDE
Descriptor:beta-glucosidase, 2-deoxy-2-fluoro-alpha-D-glucopyranose, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5BX3
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH DEOXYNOJIRIMYCIN
Descriptor:beta-glucosidase, 1-DEOXYNOJIRIMYCIN, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tankrathok, A., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5BX4
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH GLUCOIMIDAZOLE
Descriptor:beta-glucosidase, GLUCOIMIDAZOLE, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tankrathok, A., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5BX5
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH GLUCOSE
Descriptor:beta-glucosidase, BETA-D-GLUCOSE, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Hua, Y., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016