5FJS
Bacterial beta-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2)
Summary for 5FJS
Entry DOI | 10.2210/pdb5fjs/pdb |
Descriptor | GLUCOSYLCERAMIDASE, CALCIUM ION (3 entities in total) |
Functional Keywords | hydrolase, bile acid beta-glucosidase, glucosylceramidase, gba2, hereditary ataxia |
Biological source | THERMOANAEROBACTERIUM XYLANOLYTICUM |
Total number of polymer chains | 2 |
Total formula weight | 180813.36 |
Authors | Charoenwattanasatien, R.,Pengthaisong, S.,Breen, I.,Mutoha, R.,Sansenya, S.,Hua, Y.,Tankrathok, A.,Wu, L.,Songsiriritthigul, C.,Tanaka, H.,Williams, S.J.,Davies, G.J.,Kurisu, G.,Ketudat Cairns, J.R. (deposition date: 2015-10-12, release date: 2016-05-11, Last modification date: 2024-01-10) |
Primary citation | Charoenwattanasatien, R.,Pengthaisong, S.,Breen, I.,Mutoha, R.,Sansenya, S.,Hua, Y.,Tankrathok, A.,Wu, L.,Songsiriritthigul, C.,Tanaka, H.,Williams, S.J.,Davies, G.J.,Kurisu, G.,Ketudat Cairns, J.R. Bacterial Beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (Gba2) Acs Chem.Biol., 11:1891-, 2016 Cited by PubMed: 27115290DOI: 10.1021/ACSCHEMBIO.6B00192 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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